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The map label for this gene is desK [H]

Identifier: 50841897

GI number: 50841897

Start: 458331

End: 459497

Strand: Direct

Name: desK [H]

Synonym: PPA0415

Alternate gene names: 50841897

Gene position: 458331-459497 (Clockwise)

Preceding gene: 50841895

Following gene: 50841898

Centisome position: 17.9

GC content: 62.55

Gene sequence:

>1167_bases
ATGCACGAGGCTAGCAGGAAGGACTCCGCCATGGTAGTAATCGTAGGGGCATCGCATCCGATTCCCTTGCGGCGTCGCAA
CCGCAACGCCCTCGCTGCTGGTATCTGGCTCGTCTTCCTCGCCTATACCGTAGTGTCCCTTCAGAGCTCGCATTTACCGC
CATGGCGCATCGCTTTGGGCTGGGTGGGGCTGACCATCTTCGCGCTGTTCTATCTGACGCTGTTCTGGTGGCATGTTGAC
GGGCTGGAACTGTGGTACACGAAACGTCAGGTTCGTAGAAGCGCCATCGTGGGTCAGGTTGTGCTCGTGGTCTTGTGCGC
CCTGTTGGCCCTTGTCAGCCCCAAGATGGTGGCAAGTGCGCTGGTATACCCGATAGCCTTCGCTGTCTTCCAGATGCCTG
AGGTAGCCCTAGAGATCACGCTCGCCATCGAGGTCGTCGGGATAGCTGTGCTGGTGTGGACCGTGCCGGACCTGATGCCG
TGGGCGATCAGTTGGGCCATCTCGGTTGCTCTAGTGACGGTGGTGGGGGTCTTGGAGCGGACGGCCTGCCGGGAGCAGTT
GGCTTGTCAAGCAGAGCAGGACGTCCTGGCACGTCTGGAGGAACGCGAACAGGTCGCCTCTGATGTCCACGACCTGCTCG
GCCAGACGCTCACGGTTATGGCCATGAAGGCTCAGTTGGCGGAACGCCTCATTGGCACCGACCCGGACGCTGCGCGTGCC
CAGGCGGTCGAACTGCACGGATTGACGCGCCGTGCTCTGGCGCAGGTGCGAGAACTGGTCAGTGACATGGCCCACATGGG
AGTCGATGCTCAACTTGCCGCAGCTCGTACCGCACTCGAGGCTGCCGGTGTTGAGTGTGTGGTCTCCGACACGCGTACCG
ATGTCCAAGGCGGGTGCCATGGCGAGGGCTCGGAGTTCGACACGGTGCGCGGATGGGTGCTGCGCGAGGCGGTAACGAAT
GTGGTGCGTCACGCGCAGGCCCATACCTGCTGCGTCGAGATCGATGACGAGATTCTGGTCATCAGCGATAATGGTCGCGG
TCGAGGAGGCGCTCCCGAGGGCAACGGTTTAACGGGTATGCGTCGACGGGTTGAGGCAGCCGGGGGAGAGTTGTGGATCG
GGCCGGGGGAGCGTGGCCACGGTACCCGGATTGTCGTGACAGGCTGA

Upstream 100 bases:

>100_bases
GGCAGTGCTGGCGGGTAGACGTCGTCAGAACCGCTGAGAGGATCGGAGCAGACGAGAAATCCACATCGGGGACGAAATCG
ATCAGGACAACACCCCTGGA

Downstream 100 bases:

>100_bases
GGCCATGATCGACAAGACCCCGATCAGACTCGTGCTAGCCGACGACCAGACCCTTGTACGCGGAGCTCTGGCAGCCCTGC
TCGGCATGGAGGACGACCTG

Product: putative sensor histidine kinase, two-component system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MHEASRKDSAMVVIVGASHPIPLRRRNRNALAAGIWLVFLAYTVVSLQSSHLPPWRIALGWVGLTIFALFYLTLFWWHVD
GLELWYTKRQVRRSAIVGQVVLVVLCALLALVSPKMVASALVYPIAFAVFQMPEVALEITLAIEVVGIAVLVWTVPDLMP
WAISWAISVALVTVVGVLERTACREQLACQAEQDVLARLEEREQVASDVHDLLGQTLTVMAMKAQLAERLIGTDPDAARA
QAVELHGLTRRALAQVRELVSDMAHMGVDAQLAAARTALEAAGVECVVSDTRTDVQGGCHGEGSEFDTVRGWVLREAVTN
VVRHAQAHTCCVEIDDEILVISDNGRGRGGAPEGNGLTGMRRRVEAAGGELWIGPGERGHGTRIVVTG

Sequences:

>Translated_388_residues
MHEASRKDSAMVVIVGASHPIPLRRRNRNALAAGIWLVFLAYTVVSLQSSHLPPWRIALGWVGLTIFALFYLTLFWWHVD
GLELWYTKRQVRRSAIVGQVVLVVLCALLALVSPKMVASALVYPIAFAVFQMPEVALEITLAIEVVGIAVLVWTVPDLMP
WAISWAISVALVTVVGVLERTACREQLACQAEQDVLARLEEREQVASDVHDLLGQTLTVMAMKAQLAERLIGTDPDAARA
QAVELHGLTRRALAQVRELVSDMAHMGVDAQLAAARTALEAAGVECVVSDTRTDVQGGCHGEGSEFDTVRGWVLREAVTN
VVRHAQAHTCCVEIDDEILVISDNGRGRGGAPEGNGLTGMRRRVEAAGGELWIGPGERGHGTRIVVTG
>Mature_388_residues
MHEASRKDSAMVVIVGASHPIPLRRRNRNALAAGIWLVFLAYTVVSLQSSHLPPWRIALGWVGLTIFALFYLTLFWWHVD
GLELWYTKRQVRRSAIVGQVVLVVLCALLALVSPKMVASALVYPIAFAVFQMPEVALEITLAIEVVGIAVLVWTVPDLMP
WAISWAISVALVTVVGVLERTACREQLACQAEQDVLARLEEREQVASDVHDLLGQTLTVMAMKAQLAERLIGTDPDAARA
QAVELHGLTRRALAQVRELVSDMAHMGVDAQLAAARTALEAAGVECVVSDTRTDVQGGCHGEGSEFDTVRGWVLREAVTN
VVRHAQAHTCCVEIDDEILVISDNGRGRGGAPEGNGLTGMRRRVEAAGGELWIGPGERGHGTRIVVTG

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates desR by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42072; Mature: 42072

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEASRKDSAMVVIVGASHPIPLRRRNRNALAAGIWLVFLAYTVVSLQSSHLPPWRIALG
CCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
WVGLTIFALFYLTLFWWHVDGLELWYTKRQVRRSAIVGQVVLVVLCALLALVSPKMVASA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LVYPIAFAVFQMPEVALEITLAIEVVGIAVLVWTVPDLMPWAISWAISVALVTVVGVLER
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TACREQLACQAEQDVLARLEEREQVASDVHDLLGQTLTVMAMKAQLAERLIGTDPDAARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
QAVELHGLTRRALAQVRELVSDMAHMGVDAQLAAARTALEAAGVECVVSDTRTDVQGGCH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
GEGSEFDTVRGWVLREAVTNVVRHAQAHTCCVEIDDEILVISDNGRGRGGAPEGNGLTGM
CCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCEEEEECCCCCCCCCCCCCCCHHH
RRRVEAAGGELWIGPGERGHGTRIVVTG
HHHHHHCCCEEEECCCCCCCCCEEEEEC
>Mature Secondary Structure
MHEASRKDSAMVVIVGASHPIPLRRRNRNALAAGIWLVFLAYTVVSLQSSHLPPWRIALG
CCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
WVGLTIFALFYLTLFWWHVDGLELWYTKRQVRRSAIVGQVVLVVLCALLALVSPKMVASA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LVYPIAFAVFQMPEVALEITLAIEVVGIAVLVWTVPDLMPWAISWAISVALVTVVGVLER
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TACREQLACQAEQDVLARLEEREQVASDVHDLLGQTLTVMAMKAQLAERLIGTDPDAARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
QAVELHGLTRRALAQVRELVSDMAHMGVDAQLAAARTALEAAGVECVVSDTRTDVQGGCH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
GEGSEFDTVRGWVLREAVTNVVRHAQAHTCCVEIDDEILVISDNGRGRGGAPEGNGLTGM
CCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCEEEEECCCCCCCCCCCCCCCHHH
RRRVEAAGGELWIGPGERGHGTRIVVTG
HHHHHHCCCEEEECCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]