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The map label for this gene is dtd

Identifier: 50841832

GI number: 50841832

Start: 397880

End: 398317

Strand: Reverse

Name: dtd

Synonym: PPA0346

Alternate gene names: 50841832

Gene position: 398317-397880 (Counterclockwise)

Preceding gene: 50841836

Following gene: 50841830

Centisome position: 15.56

GC content: 64.38

Gene sequence:

>438_bases
ATGCGGGTCGTCATACAGAGAGCAACCAGTGCCGAGGTCGTCGTCGAGGGCCGGACGGTCGGGTCACTGACGACTCCCGG
GCTGGTGGTGCTCGTCGGGGTCACCGGTACCGACACCGCCACCACGGCCGAAAAACTGGCCGAGAAAGTGTGGGGGCTGC
GCATCCTGTCCGAGGAGAAATCTGCCAGCGACCTTAATGCCCCGCTGCTCGTCGTCAGCCAGTTCACCCTCTACGCCAGT
ACCCGTAAGGGGCGCCGCCCGTCGTGGAGTGCTGCGGCACCCGGGCCGGTGTCCGAGCCGCTGGTGGACCACTTCGTAAC
CCACCTGCGCAGCTTGGGAGCCCACGTCGAGACCGGAATCTTCGGTGCCGATATGAAGGTGGGTCTAGTCAACGACGGCC
CGATGACGATTCTCATCGACACCGATGATTGGCACTGA

Upstream 100 bases:

>100_bases
GCGGTAACACGGCACCCACCACCGCAACGGTCACCAGAACCACAAGATCAGCTTCAGCCACGTCACGATTCTACGAGGTC
AGCTGCGTAGACTCGATTCC

Downstream 100 bases:

>100_bases
ACAATCCGTACAACTCAAGATTCCTCGTACAACTGCACCGATGAGATGAGCACCGAGTCCCGGGTGGGCTCGCCGAGCGA
ACCGGGTTGGGTCGACGCGA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MRVVIQRATSAEVVVEGRTVGSLTTPGLVVLVGVTGTDTATTAEKLAEKVWGLRILSEEKSASDLNAPLLVVSQFTLYAS
TRKGRRPSWSAAAPGPVSEPLVDHFVTHLRSLGAHVETGIFGADMKVGLVNDGPMTILIDTDDWH

Sequences:

>Translated_145_residues
MRVVIQRATSAEVVVEGRTVGSLTTPGLVVLVGVTGTDTATTAEKLAEKVWGLRILSEEKSASDLNAPLLVVSQFTLYAS
TRKGRRPSWSAAAPGPVSEPLVDHFVTHLRSLGAHVETGIFGADMKVGLVNDGPMTILIDTDDWH
>Mature_145_residues
MRVVIQRATSAEVVVEGRTVGSLTTPGLVVLVGVTGTDTATTAEKLAEKVWGLRILSEEKSASDLNAPLLVVSQFTLYAS
TRKGRRPSWSAAAPGPVSEPLVDHFVTHLRSLGAHVETGIFGADMKVGLVNDGPMTILIDTDDWH

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=34.2281879194631, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1790320, Length=142, Percent_Identity=45.0704225352113, Blast_Score=114, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=37.1621621621622, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=38.6666666666667, Blast_Score=107, Evalue=7e-25,
Organism=Drosophila melanogaster, GI281361569, Length=148, Percent_Identity=43.2432432432432, Blast_Score=106, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_PROAC (Q6AAW5)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055059.1
- ProteinModelPortal:   Q6AAW5
- SMR:   Q6AAW5
- GeneID:   2931478
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA0346
- NMPDR:   fig|267747.1.peg.336
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   PACN267747:PPA0346-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15419; Mature: 15419

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: ACT_SITE 76-76

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVIQRATSAEVVVEGRTVGSLTTPGLVVLVGVTGTDTATTAEKLAEKVWGLRILSEEK
CEEEEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCEEEECCCC
SASDLNAPLLVVSQFTLYASTRKGRRPSWSAAAPGPVSEPLVDHFVTHLRSLGAHVETGI
CCCCCCCCEEEEEHEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCE
FGADMKVGLVNDGPMTILIDTDDWH
ECCCEEEEEECCCCEEEEEECCCCC
>Mature Secondary Structure
MRVVIQRATSAEVVVEGRTVGSLTTPGLVVLVGVTGTDTATTAEKLAEKVWGLRILSEEK
CEEEEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCEEEECCCC
SASDLNAPLLVVSQFTLYASTRKGRRPSWSAAAPGPVSEPLVDHFVTHLRSLGAHVETGI
CCCCCCCCEEEEEHEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCE
FGADMKVGLVNDGPMTILIDTDDWH
ECCCEEEEEECCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA