BacMap

Definition	Propionibacterium acnes KPA171202, complete genome.
Accession	NC_006085
Length	2,560,265

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The map label for this gene is ydfG [C]

Identifier: 50841836

GI number: 50841836

Start: 401405

End: 402142

Strand: Reverse

Name: ydfG [C]

Synonym: PPA0350

Alternate gene names: 50841836

Gene position: 402142-401405 (Counterclockwise)

Preceding gene: 50841837

Following gene: 50841832

Centisome position: 15.71

GC content: 61.92

Gene sequence:

>738_bases
ATGACTAAAACTGCAGTGGTCACAGGAGCGAGTTCGGGAATCGGCGCGGCCACGGCCCGCGCTCTAGCGGGCGATAGCTG
GCACGTCATCTGTGCAGCCCGCCGAGTCGAGCGCATCGAGCCACTCTCCGCCGAGATCGGTGGGCAAGCCGTAGTATGCG
ACGTGACGAGCGACGAGTCTGTCACCAACCTCGTCAAGACTGTCGGCGGCAAGGTCGATCTCCTCGTCAACAATGCTGGT
GGCGCCGTCGGTCAAGAACCCGTCACTGAGGCTGACCTCAATGCCTGGACGACGATGTACCAAACCAACGTGCTAGGCAT
GGGGCAGGTCACCAAGGCTCTCCTGCCCGCGCTCGAAATTGCTGAAGGCACCATCATCACCATCACCTCCACCGCCGCTG
AATGGGGCTACGAGGGCGGTGCCGGATACTGTGCTGCTAAATCTGGCGAGAGAGCTGTTGTCGAAGCCCTGCGCCTAGAA
CTATGTGGCCATCCGGTGCGGGTGTGCGAGGTGAGCCCCGGCATGGTGCACACCGAGGAGTTCTCCCTGGTGCGTTTCCA
CGGCGACCAGGCCAAAGCTGACAAGGTTTACCAGGGGGTCGACTCTCCCCTGGTCGCCGCTGACATTGCCGAATGCGTAC
GTTGGATCTCTGGGCTGCCCAGCCACGTCAACATTGATCGAATGATCGTCCGTCCTCGCGCCCAGGCCGCCCAGTACAAG
GTGGCACGCGAATCCTGA

Upstream 100 bases:

>100_bases
GAGTGTCGAGGTTCTTGTCAGCTGATACACGATCCTCAATCCGCTAAAGCCCCCGCAGAGGGGGCTTTAGCATGCTCCGC
AGGGGGAGGACAATAGGGCC

Downstream 100 bases:

>100_bases
TTCAGGAGGACTCCCCTGCCCGTCAGTTCAGCTGCTGGACCTCCGCGGGCAGGTGGATGTTCTCGTCGGGCTCAGCTGTC
TCGTCAACACCTCGCGAAGA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTKTAVVTGASSGIGAATARALAGDSWHVICAARRVERIEPLSAEIGGQAVVCDVTSDESVTNLVKTVGGKVDLLVNNAG
GAVGQEPVTEADLNAWTTMYQTNVLGMGQVTKALLPALEIAEGTIITITSTAAEWGYEGGAGYCAAKSGERAVVEALRLE
LCGHPVRVCEVSPGMVHTEEFSLVRFHGDQAKADKVYQGVDSPLVAADIAECVRWISGLPSHVNIDRMIVRPRAQAAQYK
VARES

Sequences:

>Translated_245_residues
MTKTAVVTGASSGIGAATARALAGDSWHVICAARRVERIEPLSAEIGGQAVVCDVTSDESVTNLVKTVGGKVDLLVNNAG
GAVGQEPVTEADLNAWTTMYQTNVLGMGQVTKALLPALEIAEGTIITITSTAAEWGYEGGAGYCAAKSGERAVVEALRLE
LCGHPVRVCEVSPGMVHTEEFSLVRFHGDQAKADKVYQGVDSPLVAADIAECVRWISGLPSHVNIDRMIVRPRAQAAQYK
VARES
>Mature_244_residues
TKTAVVTGASSGIGAATARALAGDSWHVICAARRVERIEPLSAEIGGQAVVCDVTSDESVTNLVKTVGGKVDLLVNNAGG
AVGQEPVTEADLNAWTTMYQTNVLGMGQVTKALLPALEIAEGTIITITSTAAEWGYEGGAGYCAAKSGERAVVEALRLEL
CGHPVRVCEVSPGMVHTEEFSLVRFHGDQAKADKVYQGVDSPLVAADIAECVRWISGLPSHVNIDRMIVRPRAQAAQYKV
ARES

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=30.4, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI7657478, Length=219, Percent_Identity=31.5068493150685, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI5031737, Length=202, Percent_Identity=32.1782178217822, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI7706318, Length=239, Percent_Identity=31.3807531380753, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=30.9644670050761, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI32483357, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=31.9371727748691, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI22507405, Length=183, Percent_Identity=29.5081967213115, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI19923817, Length=190, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=29.5698924731183, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI19743808, Length=189, Percent_Identity=31.7460317460317, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI7705925, Length=179, Percent_Identity=30.7262569832402, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI59889578, Length=135, Percent_Identity=31.8518518518519, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=26.4550264550265, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787820, Length=237, Percent_Identity=39.2405063291139, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=32.0987654320988, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786701, Length=215, Percent_Identity=31.1627906976744, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787905, Length=186, Percent_Identity=31.1827956989247, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082100, Length=191, Percent_Identity=31.9371727748691, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=213, Percent_Identity=32.3943661971831, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=192, Percent_Identity=31.25, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=196, Percent_Identity=31.1224489795918, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=26.5625, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=243, Percent_Identity=27.9835390946502, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=231, Percent_Identity=25.974025974026, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=195, Percent_Identity=29.7435897435897, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=193, Percent_Identity=30.5699481865285, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=191, Percent_Identity=30.3664921465969, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=244, Percent_Identity=26.6393442622951, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=207, Percent_Identity=27.0531400966184, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=256, Percent_Identity=33.203125, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6322067, Length=185, Percent_Identity=31.3513513513514, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=186, Percent_Identity=29.5698924731183, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007236, Length=248, Percent_Identity=31.0483870967742, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=203, Percent_Identity=31.5270935960591, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24663911, Length=263, Percent_Identity=30.7984790874525, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24641232, Length=255, Percent_Identity=29.8039215686275, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI28571387, Length=252, Percent_Identity=30.5555555555556, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24643142, Length=181, Percent_Identity=32.5966850828729, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648693, Length=256, Percent_Identity=29.296875, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355889, Length=256, Percent_Identity=29.296875, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281364494, Length=252, Percent_Identity=29.3650793650794, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI116007238, Length=182, Percent_Identity=32.4175824175824, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI116007234, Length=250, Percent_Identity=30, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21357041, Length=186, Percent_Identity=30.1075268817204, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358495, Length=228, Percent_Identity=27.6315789473684, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641388, Length=258, Percent_Identity=29.0697674418605, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571526, Length=186, Percent_Identity=29.5698924731183, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24639444, Length=196, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=198, Percent_Identity=26.7676767676768, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25717; Mature: 25586

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTAVVTGASSGIGAATARALAGDSWHVICAARRVERIEPLSAEIGGQAVVCDVTSDES
CCCEEEEECCCCCCCHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCEEEEEECCCHH
VTNLVKTVGGKVDLLVNNAGGAVGQEPVTEADLNAWTTMYQTNVLGMGQVTKALLPALEI
HHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AEGTIITITSTAAEWGYEGGAGYCAAKSGERAVVEALRLELCGHPVRVCEVSPGMVHTEE
CCCEEEEEEECHHHCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCC
FSLVRFHGDQAKADKVYQGVDSPLVAADIAECVRWISGLPSHVNIDRMIVRPRAQAAQYK
EEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHH
VARES
HCCCC
>Mature Secondary Structure 
TKTAVVTGASSGIGAATARALAGDSWHVICAARRVERIEPLSAEIGGQAVVCDVTSDES
CCEEEEECCCCCCCHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCEEEEEECCCHH
VTNLVKTVGGKVDLLVNNAGGAVGQEPVTEADLNAWTTMYQTNVLGMGQVTKALLPALEI
HHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AEGTIITITSTAAEWGYEGGAGYCAAKSGERAVVEALRLELCGHPVRVCEVSPGMVHTEE
CCCEEEEEEECHHHCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCEEECCC
FSLVRFHGDQAKADKVYQGVDSPLVAADIAECVRWISGLPSHVNIDRMIVRPRAQAAQYK
EEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHH
VARES
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]