Click here to switch to the map view.

The map label for this gene is hemY [H]

Identifier: 50841793

GI number: 50841793

Start: 355251

End: 356699

Strand: Reverse

Name: hemY [H]

Synonym: PPA0305

Alternate gene names: 50841793

Gene position: 356699-355251 (Counterclockwise)

Preceding gene: 50841794

Following gene: 50841792

Centisome position: 13.93

GC content: 64.39

Gene sequence:

>1449_bases
GTGAGCCGAGTAGCGACGATGAACATTTCTGATCCGCAGCACGTCGACGCCGTCGTCATTGGCGGGGGCATGGCTGGCCT
CGTGGCCGCCTGGCAGTTCACCCAGGAAGGTCTGCACCCGGTACTTGTCGAATCCCGCGGGTACACCGGCGGGCTGATTG
CCAGGTCGACGCTGGCCGGAATCAGCTACGACATCGGGGCCGAGGGGTGGGCGGTCCGTCTACCAGACACCGCTGAACTG
GCCACCGAGTTGGGATTGACGGTTGAGAAGCCGACCATCGCCCCGTCTTGGGTGTACTTCGATGACGCCTGCTTCGCGAT
GCCCGATAATGCCATTCTTGGCATCCCGGCGAACTTGTCGGACCCAGCCGTCATCATCGCCCTGGGAGCGGAAGAGGCTG
CCCGCGCCGCCGAACTTGATCGCGCACCCATGCCTGAGGATCTCCCTCGCGACCTGGGTACGCTCGTTGCCTCCCGGATG
GGGTCAGAGGTATTGCGGCGTCTCGTCACCCCGATCGCCGGGGGAATCCACGCCGCCGACCCACATCTACTGTCAGTCGA
CGTCGTCTCCCCCGGTCTGAGGGCCGCCGCCCAGGCCACCGGATCGCTAGCAGCGGGAGTTGCGCTGTGCCGCTCACGGA
TGCCAGCGGGGCCTGCAGTCGCGTCGGTAGCCGGTGGCATGTTCATCATGCCGGCCGAACTGCGTCGTCAGGCAGAACAG
GCCGGCGCGACGACCATGACCCGAGTAGGAGCTCGCGGGCTAACCCGCCACGGAGATCAGTGGCTAGTGGAGACCGCTGG
TACCTCCCGCAATCCGGATCCATCTTTGCCCCCCGTCACCGACGGCGAGATTCGTTCCTTCCTGACCCCTCGGGTCGTCG
TGGCCTGTTCAGCTGGACCTGCCACAAAACTGCTCAGCAATGTCATCGACACCGTTGGGCCCGAGTTGGCACCGGGCGCG
CCGATCGGCCACGTCAATCTCGCCTTGCAGGCACCCGCGCTGGACTCGAGCCCACGCGGAAACGGCATGCTGGTGGCCCC
CGGAACGACCACCGTTACTGCCAAGGCACTTACTCACATGTCGGCGAAGTGGCCCAGCTTGAGAGAATCGTGTCCCGAAG
GTCTCCACTTGCTACGGGTTTCCTATGGTCGATCTGGTGAAGCGAATGTCGCTTTGAGCGTCGATCAGGCTCTAACGGAC
GCTTCCGTCCTACTCGGCGTGGACCTCTCGGCGGAGCAGGTCGTAGACTCCCAGATCATTCACTGGACAGGTTCCCTCGC
ACCGACGACTCCACAGGCCCGAGCATGGCGCGATGGTCTGCACCGCCAGCTAGAGGTATTGAACCAGTCTGGACAGGGAC
GGATCGGCTTAGTGGGGTCGTGGGCATCGGGTTCGGGCATTGCCGCTCTGGTGCCGCAGGCCCGCCGAACTGTCCGTCAA
CTTGTCTGA

Upstream 100 bases:

>100_bases
GACGTCAGGCCCCTGGACACGTCGTCAATCTGGGTCACGGTGTGCCCTCCAACACCGACCCCAACGTCTTGACACGGCTG
GTGGAGCTGGTGCACTCCCT

Downstream 100 bases:

>100_bases
TTGCAGGCTGGAATCGGCGTCGGTACTGAGTGCCACAATAGGCAATATGTCTGCGATCCGTCTGGGAACCCGTGCCAGCA
CTCTGGCCACTACTCAATCA

Product: putative protoporphyrinogen oxidase, HemY

Products: NA

Alternate protein names: PPO [H]

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MSRVATMNISDPQHVDAVVIGGGMAGLVAAWQFTQEGLHPVLVESRGYTGGLIARSTLAGISYDIGAEGWAVRLPDTAEL
ATELGLTVEKPTIAPSWVYFDDACFAMPDNAILGIPANLSDPAVIIALGAEEAARAAELDRAPMPEDLPRDLGTLVASRM
GSEVLRRLVTPIAGGIHAADPHLLSVDVVSPGLRAAAQATGSLAAGVALCRSRMPAGPAVASVAGGMFIMPAELRRQAEQ
AGATTMTRVGARGLTRHGDQWLVETAGTSRNPDPSLPPVTDGEIRSFLTPRVVVACSAGPATKLLSNVIDTVGPELAPGA
PIGHVNLALQAPALDSSPRGNGMLVAPGTTTVTAKALTHMSAKWPSLRESCPEGLHLLRVSYGRSGEANVALSVDQALTD
ASVLLGVDLSAEQVVDSQIIHWTGSLAPTTPQARAWRDGLHRQLEVLNQSGQGRIGLVGSWASGSGIAALVPQARRTVRQ
LV

Sequences:

>Translated_482_residues
MSRVATMNISDPQHVDAVVIGGGMAGLVAAWQFTQEGLHPVLVESRGYTGGLIARSTLAGISYDIGAEGWAVRLPDTAEL
ATELGLTVEKPTIAPSWVYFDDACFAMPDNAILGIPANLSDPAVIIALGAEEAARAAELDRAPMPEDLPRDLGTLVASRM
GSEVLRRLVTPIAGGIHAADPHLLSVDVVSPGLRAAAQATGSLAAGVALCRSRMPAGPAVASVAGGMFIMPAELRRQAEQ
AGATTMTRVGARGLTRHGDQWLVETAGTSRNPDPSLPPVTDGEIRSFLTPRVVVACSAGPATKLLSNVIDTVGPELAPGA
PIGHVNLALQAPALDSSPRGNGMLVAPGTTTVTAKALTHMSAKWPSLRESCPEGLHLLRVSYGRSGEANVALSVDQALTD
ASVLLGVDLSAEQVVDSQIIHWTGSLAPTTPQARAWRDGLHRQLEVLNQSGQGRIGLVGSWASGSGIAALVPQARRTVRQ
LV
>Mature_481_residues
SRVATMNISDPQHVDAVVIGGGMAGLVAAWQFTQEGLHPVLVESRGYTGGLIARSTLAGISYDIGAEGWAVRLPDTAELA
TELGLTVEKPTIAPSWVYFDDACFAMPDNAILGIPANLSDPAVIIALGAEEAARAAELDRAPMPEDLPRDLGTLVASRMG
SEVLRRLVTPIAGGIHAADPHLLSVDVVSPGLRAAAQATGSLAAGVALCRSRMPAGPAVASVAGGMFIMPAELRRQAEQA
GATTMTRVGARGLTRHGDQWLVETAGTSRNPDPSLPPVTDGEIRSFLTPRVVVACSAGPATKLLSNVIDTVGPELAPGAP
IGHVNLALQAPALDSSPRGNGMLVAPGTTTVTAKALTHMSAKWPSLRESCPEGLHLLRVSYGRSGEANVALSVDQALTDA
SVLLGVDLSAEQVVDSQIIHWTGSLAPTTPQARAWRDGLHRQLEVLNQSGQGRIGLVGSWASGSGIAALVPQARRTVRQL
V

Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX [H]

COG id: COG1232

COG function: function code H; Protoporphyrinogen oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protoporphyrinogen oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR004572 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: =1.3.3.4 [H]

Molecular weight: Translated: 49924; Mature: 49792

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVATMNISDPQHVDAVVIGGGMAGLVAAWQFTQEGLHPVLVESRGYTGGLIARSTLAG
CCCEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHC
ISYDIGAEGWAVRLPDTAELATELGLTVEKPTIAPSWVYFDDACFAMPDNAILGIPANLS
CEEECCCCCEEEECCCHHHHHHHHCCEEECCCCCCCEEEECCEEEECCCCCEEECCCCCC
DPAVIIALGAEEAARAAELDRAPMPEDLPRDLGTLVASRMGSEVLRRLVTPIAGGIHAAD
CCEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PHLLSVDVVSPGLRAAAQATGSLAAGVALCRSRMPAGPAVASVAGGMFIMPAELRRQAEQ
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEECHHHHHHHHH
AGATTMTRVGARGLTRHGDQWLVETAGTSRNPDPSLPPVTDGEIRSFLTPRVVVACSAGP
CCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCC
ATKLLSNVIDTVGPELAPGAPIGHVNLALQAPALDSSPRGNGMLVAPGTTTVTAKALTHM
HHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCEEHHHHHHHH
SAKWPSLRESCPEGLHLLRVSYGRSGEANVALSVDQALTDASVLLGVDLSAEQVVDSQII
HCCCCHHHHHCHHHEEEEEEECCCCCCCEEEEEHHHHHCCCEEEEECCCCHHHHHHHHHE
HWTGSLAPTTPQARAWRDGLHRQLEVLNQSGQGRIGLVGSWASGSGIAALVPQARRTVRQ
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHH
LV
HC
>Mature Secondary Structure 
SRVATMNISDPQHVDAVVIGGGMAGLVAAWQFTQEGLHPVLVESRGYTGGLIARSTLAG
CCEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHC
ISYDIGAEGWAVRLPDTAELATELGLTVEKPTIAPSWVYFDDACFAMPDNAILGIPANLS
CEEECCCCCEEEECCCHHHHHHHHCCEEECCCCCCCEEEECCEEEECCCCCEEECCCCCC
DPAVIIALGAEEAARAAELDRAPMPEDLPRDLGTLVASRMGSEVLRRLVTPIAGGIHAAD
CCEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PHLLSVDVVSPGLRAAAQATGSLAAGVALCRSRMPAGPAVASVAGGMFIMPAELRRQAEQ
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEECHHHHHHHHH
AGATTMTRVGARGLTRHGDQWLVETAGTSRNPDPSLPPVTDGEIRSFLTPRVVVACSAGP
CCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCC
ATKLLSNVIDTVGPELAPGAPIGHVNLALQAPALDSSPRGNGMLVAPGTTTVTAKALTHM
HHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCEEHHHHHHHH
SAKWPSLRESCPEGLHLLRVSYGRSGEANVALSVDQALTDASVLLGVDLSAEQVVDSQII
HCCCCHHHHHCHHHEEEEEEECCCCCCCEEEEEHHHHHCCCEEEEECCCCHHHHHHHHHE
HWTGSLAPTTPQARAWRDGLHRQLEVLNQSGQGRIGLVGSWASGSGIAALVPQARRTVRQ
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHH
LV
HC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]