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The map label for this gene is hrcA [H]

Identifier: 50365235

GI number: 50365235

Start: 487744

End: 488772

Strand: Reverse

Name: hrcA [H]

Synonym: Mfl417

Alternate gene names: 50365235

Gene position: 488772-487744 (Counterclockwise)

Preceding gene: 50365236

Following gene: 50365234

Centisome position: 61.62

GC content: 25.95

Gene sequence:

>1029_bases
ATGTTAAGCGAAAGACAAGCTAAAATTTTAAAAGTAATTGTTTCAGAATATATTAAGACTAACCAAGCTGTTAGTTCTAA
AAGAATTCAAGAATTACTTAACATAAAAGTTTCAAGTGCAACTATCAGAAATGATTCAGCAGCACTTGAAGAAATGAATT
TTTTAGAGAAGCAACACACATCATCTGGGAGAGTTCCTTCAACAAAGGGATACAGATATTATGTTGATCACTTAATGGAA
TTTGATGATTATAATGAAAGTTTAAAAGAAAACTTAAAATCAATTTTATTTCAACGCGGAACAAAAATTGAAAATGTTTT
AGAACAAGCAAGTCAAATAATTAGTGAAATGACTAAAATGACAGCAATTGTGACAAAGCAAAATTTAAATAGTGAACTAA
TGGTCAAAAAAATAGACCTAATTCCATTATCAGAAACTATGGCATCAGTTATTTTTATTCTTTCAAATGGAGAAATGCAA
AATCAATTATTCAATTTAAAAGATATTTCTTTATCAGACTTATCAATATCAATAAAAATATTTTCAGATTGTTTAGTTGA
TACTCCGGTTAAAGAAATTGAAAATAACATATCACTTATCAGACCTAACTTAGAAACAACTGTTAAAAACTATGATTTAA
TTTTAGAAACTTTTATGTCAAACATTTTACAAACAAAAGAATCTAAAAAAGAAATTGTTGGAATGAAAAACATGTTAGAA
AATCCAGAATTTAATGATACAGATAAACTTAGAAAAGTTATTAACATTATGGAAAACATGTCACCATTTGATTGATTTGA
TGTAAGTTATAGTTCAAATCAAAAAATGATTCAAATAAGCACAAAAATAGGTGAAGAAATTTCAGAAGATTTAAGTGATA
TTTCAATTGTTGAAACCGCAATTAAAACAGAACAGGGTTCAACAATGTTAACTTTGGTTGGGCCTAAAAGAGTTGATTAT
TCTCAAGCTAATCAATTAATTAACTTGATAGTAGAAATAATAAATGGAGATGATCATAAAAATGAATAA

Upstream 100 bases:

>100_bases
AACAGTTGAAAATGATGACTTTGAATTAACAAAAATTAGAAATTAAGAAAAAAAGTAGCAATCTAATGTATAGAGTGCTA
AAATAAAAATAGGTGATCAA

Downstream 100 bases:

>100_bases
CGAAAAAGAATTAAAAAAAGAAGAAACTTCAGTTGAGAATAAAGAGAAAAAAGTTGCAACTGAAGAAATCAAAAAAGAGA
AAAAAGATTATAAAAAAATA

Product: heat inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLSERQAKILKVIVSEYIKTNQAVSSKRIQELLNIKVSSATIRNDSAALEEMNFLEKQHTSSGRVPSTKGYRYYVDHLME
FDDYNESLKENLKSILFQRGTKIENVLEQASQIISEMTKMTAIVTKQNLNSELMVKKIDLIPLSETMASVIFILSNGEMQ
NQLFNLKDISLSDLSISIKIFSDCLVDTPVKEIENNISLIRPNLETTVKNYDLILETFMSNILQTKESKKEIVGMKNMLE
NPEFNDTDKLRKVINIMENMSPFDWFDVSYSSNQKMIQISTKIGEEISEDLSDISIVETAIKTEQGSTMLTLVGPKRVDY
SQANQLINLIVEIINGDDHKNE

Sequences:

>Translated_342_residues
MLSERQAKILKVIVSEYIKTNQAVSSKRIQELLNIKVSSATIRNDSAALEEMNFLEKQHTSSGRVPSTKGYRYYVDHLME
FDDYNESLKENLKSILFQRGTKIENVLEQASQIISEMTKMTAIVTKQNLNSELMVKKIDLIPLSETMASVIFILSNGEMQ
NQLFNLKDISLSDLSISIKIFSDCLVDTPVKEIENNISLIRPNLETTVKNYDLILETFMSNILQTKESKKEIVGMKNMLE
NPEFNDTDKLRKVINIMENMSPFD*FDVSYSSNQKMIQISTKIGEEISEDLSDISIVETAIKTEQGSTMLTLVGPKRVDY
SQANQLINLIVEIINGDDHKNE
>Mature_342_residues
MLSERQAKILKVIVSEYIKTNQAVSSKRIQELLNIKVSSATIRNDSAALEEMNFLEKQHTSSGRVPSTKGYRYYVDHLME
FDDYNESLKENLKSILFQRGTKIENVLEQASQIISEMTKMTAIVTKQNLNSELMVKKIDLIPLSETMASVIFILSNGEMQ
NQLFNLKDISLSDLSISIKIFSDCLVDTPVKEIENNISLIRPNLETTVKNYDLILETFMSNILQTKESKKEIVGMKNMLE
NPEFNDTDKLRKVINIMENMSPFD*FDVSYSSNQKMIQISTKIGEEISEDLSDISIVETAIKTEQGSTMLTLVGPKRVDY
SQANQLINLIVEIINGDDHKNE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38781; Mature: 38781

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSERQAKILKVIVSEYIKTNQAVSSKRIQELLNIKVSSATIRNDSAALEEMNFLEKQHT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCHHHHHHHHHHHHHCC
SSGRVPSTKGYRYYVDHLMEFDDYNESLKENLKSILFQRGTKIENVLEQASQIISEMTKM
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TAIVTKQNLNSELMVKKIDLIPLSETMASVIFILSNGEMQNQLFNLKDISLSDLSISIKI
HHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEEE
FSDCLVDTPVKEIENNISLIRPNLETTVKNYDLILETFMSNILQTKESKKEIVGMKNMLE
HHHHHHCCCHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NPEFNDTDKLRKVINIMENMSPFDFDVSYSSNQKMIQISTKIGEEISEDLSDISIVETAI
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
KTEQGSTMLTLVGPKRVDYSQANQLINLIVEIINGDDHKNE
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLSERQAKILKVIVSEYIKTNQAVSSKRIQELLNIKVSSATIRNDSAALEEMNFLEKQHT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCHHHHHHHHHHHHHCC
SSGRVPSTKGYRYYVDHLMEFDDYNESLKENLKSILFQRGTKIENVLEQASQIISEMTKM
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TAIVTKQNLNSELMVKKIDLIPLSETMASVIFILSNGEMQNQLFNLKDISLSDLSISIKI
HHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEEE
FSDCLVDTPVKEIENNISLIRPNLETTVKNYDLILETFMSNILQTKESKKEIVGMKNMLE
HHHHHHCCCHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NPEFNDTDKLRKVINIMENMSPFDFDVSYSSNQKMIQISTKIGEEISEDLSDISIVETAI
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
KTEQGSTMLTLVGPKRVDYSQANQLINLIVEIINGDDHKNE
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA