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The map label for this gene is udk [H]

Identifier: 50365122

GI number: 50365122

Start: 352766

End: 353392

Strand: Direct

Name: udk [H]

Synonym: Mfl306

Alternate gene names: 50365122

Gene position: 352766-353392 (Clockwise)

Preceding gene: 50365121

Following gene: 50365124

Centisome position: 44.47

GC content: 29.19

Gene sequence:

>627_bases
ATGTCAAAAAATGTAACTTTAATACTTATAGCTGGTGGAACAGCATCAGGAAAAACAACTGTTGCTGATAGAATAGCTAA
TGAAATTTTAAAAGGTAAATCGGTAACTCATATTTCAATGGATAATTATTATAAAGATTTTGGTGAATTGACTTTAGAAG
AAAGAAGGAAAATAAACTTTGATCATCCAAATAGTGTGGATACTGAACTACTTTTAAATGACTTGCAAGCTTTAAAAGAC
TATCAACCAATCAAGGTGCCGGTTTATGATTTTAAAACTTCTTCAAGAACCAAAGAAACAATTACAGTTAAACCTAGTGA
TGTTGTAATACTTGATGGAATTTTTGCACTAGCTATTAAAGAGATTAGAAAACTTGGAGATATCAAAATTTTTATAAAAA
CAGCTAATGATTTAAGGTTTATTAGACGTTTACAAAGAGATGTAAATGAAAGAGGGAGAACTTTAGAAAGTGTTGTTGAA
CAATACTTAAATGAAGTTAAACCAATGCATGATGCATTTATTGGGCCAAGTATTGAATACGCTGATTTAATAATTCCTTA
TAAAGAGGGGAATGAAGTTGCAGTTGATTTAGTAGCAACTAAAATATTAACATTGTTAACAGAGTAA

Upstream 100 bases:

>100_bases
AATATCAATAAGTTTGGTTTTGATGAGATTCAAGAAAGAACCGTTGCATTAGCTAAAATAATTTCTGAAAATATTTATTA
TAAATAATAGGAGTAGAAAA

Downstream 100 bases:

>100_bases
AAAAACATAGATGTCTTTTTAAATAAGGCCTCTATGTTTTTTGATTAAAAATGAAATTGTTTTGCGATTTAATCAAAATG
CTTGAAATGTTAAATTAGAA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSKNVTLILIAGGTASGKTTVADRIANEILKGKSVTHISMDNYYKDFGELTLEERRKINFDHPNSVDTELLLNDLQALKD
YQPIKVPVYDFKTSSRTKETITVKPSDVVILDGIFALAIKEIRKLGDIKIFIKTANDLRFIRRLQRDVNERGRTLESVVE
QYLNEVKPMHDAFIGPSIEYADLIIPYKEGNEVAVDLVATKILTLLTE

Sequences:

>Translated_208_residues
MSKNVTLILIAGGTASGKTTVADRIANEILKGKSVTHISMDNYYKDFGELTLEERRKINFDHPNSVDTELLLNDLQALKD
YQPIKVPVYDFKTSSRTKETITVKPSDVVILDGIFALAIKEIRKLGDIKIFIKTANDLRFIRRLQRDVNERGRTLESVVE
QYLNEVKPMHDAFIGPSIEYADLIIPYKEGNEVAVDLVATKILTLLTE
>Mature_207_residues
SKNVTLILIAGGTASGKTTVADRIANEILKGKSVTHISMDNYYKDFGELTLEERRKINFDHPNSVDTELLLNDLQALKDY
QPIKVPVYDFKTSSRTKETITVKPSDVVILDGIFALAIKEIRKLGDIKIFIKTANDLRFIRRLQRDVNERGRTLESVVEQ
YLNEVKPMHDAFIGPSIEYADLIIPYKEGNEVAVDLVATKILTLLTE

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=209, Percent_Identity=43.0622009569378, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI57863312, Length=209, Percent_Identity=43.0622009569378, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI18699734, Length=211, Percent_Identity=41.2322274881517, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI13899253, Length=211, Percent_Identity=39.8104265402844, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI209863022, Length=148, Percent_Identity=38.5135135135135, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI87082034, Length=204, Percent_Identity=43.6274509803922, Blast_Score=174, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17539894, Length=208, Percent_Identity=40.8653846153846, Blast_Score=160, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17539892, Length=208, Percent_Identity=40.8653846153846, Blast_Score=160, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71981181, Length=202, Percent_Identity=36.6336633663366, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324339, Length=191, Percent_Identity=33.5078534031414, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573516, Length=202, Percent_Identity=44.0594059405941, Blast_Score=165, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28573514, Length=202, Percent_Identity=44.0594059405941, Blast_Score=165, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28573512, Length=202, Percent_Identity=44.0594059405941, Blast_Score=165, Evalue=1e-41,
Organism=Drosophila melanogaster, GI45550449, Length=202, Percent_Identity=44.0594059405941, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI221458995, Length=216, Percent_Identity=38.8888888888889, Blast_Score=153, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24649624, Length=217, Percent_Identity=38.7096774193548, Blast_Score=153, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 23496; Mature: 23365

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNVTLILIAGGTASGKTTVADRIANEILKGKSVTHISMDNYYKDFGELTLEERRKINF
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCC
DHPNSVDTELLLNDLQALKDYQPIKVPVYDFKTSSRTKETITVKPSDVVILDGIFALAIK
CCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCEEEEHHHHHHHHH
EIRKLGDIKIFIKTANDLRFIRRLQRDVNERGRTLESVVEQYLNEVKPMHDAFIGPSIEY
HHHHHCCEEEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHCCCCCCE
ADLIIPYKEGNEVAVDLVATKILTLLTE
EEEEEEECCCCEEHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKNVTLILIAGGTASGKTTVADRIANEILKGKSVTHISMDNYYKDFGELTLEERRKINF
CCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCC
DHPNSVDTELLLNDLQALKDYQPIKVPVYDFKTSSRTKETITVKPSDVVILDGIFALAIK
CCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCEEEEHHHHHHHHH
EIRKLGDIKIFIKTANDLRFIRRLQRDVNERGRTLESVVEQYLNEVKPMHDAFIGPSIEY
HHHHHCCEEEEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHCCCCCCE
ADLIIPYKEGNEVAVDLVATKILTLLTE
EEEEEEECCCCEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA