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The map label for this gene is cdsA [H]

Identifier: 50365102

GI number: 50365102

Start: 327675

End: 328730

Strand: Direct

Name: cdsA [H]

Synonym: Mfl286

Alternate gene names: 50365102

Gene position: 327675-328730 (Clockwise)

Preceding gene: 50365101

Following gene: 50365103

Centisome position: 41.31

GC content: 23.77

Gene sequence:

>1056_bases
ATGACTAATAAAATAGAATCCAATCAAAGTAAATTTTTAAATTTAAAAAATAATAATTTCTTTATAAGATTTTCATCAAG
TGTAATTATAGTTGCTATGATAATTTTATTTTTATCAACAGCAATATTGAGTGAAGAATTATGAGTTCATTTAAGCGATA
AAAATAAAGCAGAAGCTGTTAGTCAAGCTCTTGGAATTGTTATGCTATGCATATCTGTTGCTATATTAATGTTTTGTATA
TATGAATTATCTACATCATTAAAGATTAAAAATAAAGTTTTCATAATAATTATGGAATTATTAGCTTTGGGACTATTTTT
AGCACCGATAACTTCAATAAGAAATCTAAATGATTTATTCATTTACCAAGATTGAGTTTTAAAAGCTAAACTGGCTGAAT
GATATATGCAATTTATTTATTTAATTATATTTTTAAGTGCTTCAACAATAACAGGTTATTTATCAGGAGTTAATCTTAAA
AAAATGGTTATGATCATTGGAACTTCATTAATTATAATATTTGGTATGAAAGGATTTACTTACATATCACTAACAAATGA
TTATAATTCACAAGATTATTCAAGTATTAGATTTGGTTATGTAACAGCAATTTGAATTTGATTAATTGTTATATTAACAG
ATACATTTGCTTATATATTTGGTATAGCATTTGGTAAACACAAAATGGCTCCAAAAATTTCCCCTAAAAAAAGTTGAGAA
GGTGCAATCGGAGGATTTACAACAGCTTTTATAGTTTCAGTAACAATGGCAATATTATTTTTCTTCTTTGTTAATTCTCA
TTCTATTTTTAAAGATTATATGAGTAATATTCAAACCAATTTAGGAACAGGATTAGTTATATTCATGTATATTCTTTTAG
CATCTTTAATTTCATTTATAGGTCAATTAGGAGATTTGTTTTTTTCACTAATTAAAAGAAAAAATGATATAAAAGATTTT
TCAAATTTAATACCAGGCCATGGAGGAGTTTTAGATAGACTTGACTCATTCATGTTAGTATTCTTATTTATGTATTTATT
TACATTAATCAATTAG

Upstream 100 bases:

>100_bases
AAATAAAAAAAATAATAAAAAATAACCTGTGTTTAAGGGTTAAAAAACAATGCAAAATTTGCTAAAATTAATATAATTGT
ATTTTAAAGAAAGGATCATT

Downstream 100 bases:

>100_bases
TTTAAGGAGTTTATATGGGAAGTGTAATGATAGTAATTTTATCAATATTAATTTCAATCATTGTTGTATTGGTGCTAATT
ACACTTCATGAACTAGGACA

Product: CDP-diglyceride synthetase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTNKIESNQSKFLNLKNNNFFIRFSSSVIIVAMIILFLSTAILSEELWVHLSDKNKAEAVSQALGIVMLCISVAILMFCI
YELSTSLKIKNKVFIIIMELLALGLFLAPITSIRNLNDLFIYQDWVLKAKLAEWYMQFIYLIIFLSASTITGYLSGVNLK
KMVMIIGTSLIIIFGMKGFTYISLTNDYNSQDYSSIRFGYVTAIWIWLIVILTDTFAYIFGIAFGKHKMAPKISPKKSWE
GAIGGFTTAFIVSVTMAILFFFFVNSHSIFKDYMSNIQTNLGTGLVIFMYILLASLISFIGQLGDLFFSLIKRKNDIKDF
SNLIPGHGGVLDRLDSFMLVFLFMYLFTLIN

Sequences:

>Translated_351_residues
MTNKIESNQSKFLNLKNNNFFIRFSSSVIIVAMIILFLSTAILSEEL*VHLSDKNKAEAVSQALGIVMLCISVAILMFCI
YELSTSLKIKNKVFIIIMELLALGLFLAPITSIRNLNDLFIYQD*VLKAKLAE*YMQFIYLIIFLSASTITGYLSGVNLK
KMVMIIGTSLIIIFGMKGFTYISLTNDYNSQDYSSIRFGYVTAI*I*LIVILTDTFAYIFGIAFGKHKMAPKISPKKS*E
GAIGGFTTAFIVSVTMAILFFFFVNSHSIFKDYMSNIQTNLGTGLVIFMYILLASLISFIGQLGDLFFSLIKRKNDIKDF
SNLIPGHGGVLDRLDSFMLVFLFMYLFTLIN
>Mature_350_residues
TNKIESNQSKFLNLKNNNFFIRFSSSVIIVAMIILFLSTAILSEEL*VHLSDKNKAEAVSQALGIVMLCISVAILMFCIY
ELSTSLKIKNKVFIIIMELLALGLFLAPITSIRNLNDLFIYQD*VLKAKLAE*YMQFIYLIIFLSASTITGYLSGVNLKK
MVMIIGTSLIIIFGMKGFTYISLTNDYNSQDYSSIRFGYVTAI*I*LIVILTDTFAYIFGIAFGKHKMAPKISPKKS*EG
AIGGFTTAFIVSVTMAILFFFFVNSHSIFKDYMSNIQTNLGTGLVIFMYILLASLISFIGQLGDLFFSLIKRKNDIKDFS
NLIPGHGGVLDRLDSFMLVFLFMYLFTLIN

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=222, Percent_Identity=31.5315315315315, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787677, Length=125, Percent_Identity=34.4, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539016, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17539014, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319503, Length=156, Percent_Identity=31.4102564102564, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 38599; Mature: 38468

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKIESNQSKFLNLKNNNFFIRFSSSVIIVAMIILFLSTAILSEELVHLSDKNKAEAVS
CCCCCCCCHHHEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QALGIVMLCISVAILMFCIYELSTSLKIKNKVFIIIMELLALGLFLAPITSIRNLNDLFI
HHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YQDVLKAKLAEYMQFIYLIIFLSASTITGYLSGVNLKKMVMIIGTSLIIIFGMKGFTYIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
LTNDYNSQDYSSIRFGYVTAIILIVILTDTFAYIFGIAFGKHKMAPKISPKKSEGAIGGF
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
TTAFIVSVTMAILFFFFVNSHSIFKDYMSNIQTNLGTGLVIFMYILLASLISFIGQLGDL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
FFSLIKRKNDIKDFSNLIPGHGGVLDRLDSFMLVFLFMYLFTLIN
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNKIESNQSKFLNLKNNNFFIRFSSSVIIVAMIILFLSTAILSEELVHLSDKNKAEAVS
CCCCCCCHHHEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QALGIVMLCISVAILMFCIYELSTSLKIKNKVFIIIMELLALGLFLAPITSIRNLNDLFI
HHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YQDVLKAKLAEYMQFIYLIIFLSASTITGYLSGVNLKKMVMIIGTSLIIIFGMKGFTYIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
LTNDYNSQDYSSIRFGYVTAIILIVILTDTFAYIFGIAFGKHKMAPKISPKKSEGAIGGF
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
TTAFIVSVTMAILFFFFVNSHSIFKDYMSNIQTNLGTGLVIFMYILLASLISFIGQLGDL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
FFSLIKRKNDIKDFSNLIPGHGGVLDRLDSFMLVFLFMYLFTLIN
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA