Click here to switch to the map view.

The map label for this gene is yaeL [C]

Identifier: 50365103

GI number: 50365103

Start: 328745

End: 330013

Strand: Direct

Name: yaeL [C]

Synonym: Mfl287

Alternate gene names: 50365103

Gene position: 328745-330013 (Clockwise)

Preceding gene: 50365102

Following gene: 50365104

Centisome position: 41.44

GC content: 27.74

Gene sequence:

>1269_bases
ATGGGAAGTGTAATGATAGTAATTTTATCAATATTAATTTCAATCATTGTTGTATTGGTGCTAATTACACTTCATGAACT
AGGACATTTCATTGTAGCAAAGTTATCAAAAGCTTATGTCTTTGAATTTGCAATTGGTTTTGGTCCTAAATTGTTTGTTA
TAAAAACAAAAGAAACTTGATATTCAGTTAGACTAATACCTTTGGGTGGTTATGTTTCTATAGCTAGCGATTTTGCTGAA
CCACCAAAAGGCAGAGAAGAAGAATTTGAAAAAATACCTGACATAAGAAAAATTGATTATGCTATAAAATGAAAGAAAAC
TTTATTTATTTTATTTGGACCATTAATGAATTTATTTATAGCCTATATTTTAATCTTTTCAGTAATGTTTGGAGTTGGAT
ACAAACCAAGTGATCCAAATTTTTACGGTCAAAACTTTTCAACGACTTCTATTGCTTATAAAATGATATATGAAAACGAA
AAAGAAGGACAAACACCACCAGTAACAGAAGAAAAATATATTTACAATGATTTGCAAATTGCAATTACAGGATGAAATGT
AAAAATTGAAGAAAAACCTTTTGAATTTAAAACTACTAATTCTGCTAATTTAGCACCTACGTATTTACAAATTTCAAAAA
TGTTTAATGACGGTAAAAAAGATATCTTGAATTATTTATATAAAAATAATATTGAGTCAGGTAATGTTGAATATCAATTT
AGTTATGTTAATTTAACTAATGATTATTCAGGGGATGTTAAATCTGATGGTAAAACAGAGTTTAAACTTATAAGTGAAGA
ACAAACAATAGCTGAATGAAGAAAAACAGGTCAAATAAATGGTATAGCAATTGCACCACCAGATAGACATTTTAAAAATG
GTGCTCAAAAATTTGGTTATACATTCGTTGAAACATGAAATCAATCATTTTCATTATTAGTAGGTATTGGTAAATTCTTT
ACAGGTGATTTTAGTGCTATTTCTGGTCCTGTTGGTATTGCTAAATCATCAATTGGAACTACAGGTGCTGCAACTACATC
AATGGTTGCCAGTCGTTTGTTTTATGTTTCTTCTATATCAGCAAACTTATTTATGCTAAATATGCTTCCATTTCCACCAT
TAGATGGATATAAGTTTTGAGAAACATTAGTAGAATGAGTAACCAGAAAAGAAGTTAGTCAAAAATCAAAAACAATAATT
TATGCAGCTGGAGCAATTTTATTAGTAACTTTCATAGTAATAGTAACAATTAAAGATTTTATAGTTTAA

Upstream 100 bases:

>100_bases
TACCAGGCCATGGAGGAGTTTTAGATAGACTTGACTCATTCATGTTAGTATTCTTATTTATGTATTTATTTACATTAATC
AATTAGTTTAAGGAGTTTAT

Downstream 100 bases:

>100_bases
AAAAGGAGCTTATATGTCAGACAATAAGGTATTAGAATTATTTCAAAAATTGAAGATCAATTTAAATGAAGGCGAACTTT
CATATTTTGAACATTCTGAA

Product: membrane associated Zn-dependent protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MGSVMIVILSILISIIVVLVLITLHELGHFIVAKLSKAYVFEFAIGFGPKLFVIKTKETWYSVRLIPLGGYVSIASDFAE
PPKGREEEFEKIPDIRKIDYAIKWKKTLFILFGPLMNLFIAYILIFSVMFGVGYKPSDPNFYGQNFSTTSIAYKMIYENE
KEGQTPPVTEEKYIYNDLQIAITGWNVKIEEKPFEFKTTNSANLAPTYLQISKMFNDGKKDILNYLYKNNIESGNVEYQF
SYVNLTNDYSGDVKSDGKTEFKLISEEQTIAEWRKTGQINGIAIAPPDRHFKNGAQKFGYTFVETWNQSFSLLVGIGKFF
TGDFSAISGPVGIAKSSIGTTGAATTSMVASRLFYVSSISANLFMLNMLPFPPLDGYKFWETLVEWVTRKEVSQKSKTII
YAAGAILLVTFIVIVTIKDFIV

Sequences:

>Translated_422_residues
MGSVMIVILSILISIIVVLVLITLHELGHFIVAKLSKAYVFEFAIGFGPKLFVIKTKET*YSVRLIPLGGYVSIASDFAE
PPKGREEEFEKIPDIRKIDYAIK*KKTLFILFGPLMNLFIAYILIFSVMFGVGYKPSDPNFYGQNFSTTSIAYKMIYENE
KEGQTPPVTEEKYIYNDLQIAITG*NVKIEEKPFEFKTTNSANLAPTYLQISKMFNDGKKDILNYLYKNNIESGNVEYQF
SYVNLTNDYSGDVKSDGKTEFKLISEEQTIAE*RKTGQINGIAIAPPDRHFKNGAQKFGYTFVET*NQSFSLLVGIGKFF
TGDFSAISGPVGIAKSSIGTTGAATTSMVASRLFYVSSISANLFMLNMLPFPPLDGYKF*ETLVE*VTRKEVSQKSKTII
YAAGAILLVTFIVIVTIKDFIV
>Mature_421_residues
GSVMIVILSILISIIVVLVLITLHELGHFIVAKLSKAYVFEFAIGFGPKLFVIKTKET*YSVRLIPLGGYVSIASDFAEP
PKGREEEFEKIPDIRKIDYAIK*KKTLFILFGPLMNLFIAYILIFSVMFGVGYKPSDPNFYGQNFSTTSIAYKMIYENEK
EGQTPPVTEEKYIYNDLQIAITG*NVKIEEKPFEFKTTNSANLAPTYLQISKMFNDGKKDILNYLYKNNIESGNVEYQFS
YVNLTNDYSGDVKSDGKTEFKLISEEQTIAE*RKTGQINGIAIAPPDRHFKNGAQKFGYTFVET*NQSFSLLVGIGKFFT
GDFSAISGPVGIAKSSIGTTGAATTSMVASRLFYVSSISANLFMLNMLPFPPLDGYKF*ETLVE*VTRKEVSQKSKTIIY
AAGAILLVTFIVIVTIKDFIV

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=473, Percent_Identity=26.4270613107822, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 46129; Mature: 45998

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSVMIVILSILISIIVVLVLITLHELGHFIVAKLSKAYVFEFAIGFGPKLFVIKTKETY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEECCCE
SVRLIPLGGYVSIASDFAEPPKGREEEFEKIPDIRKIDYAIKKKTLFILFGPLMNLFIAY
EEEEEEECCHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHEEEEEEHHHHHHHHHHH
ILIFSVMFGVGYKPSDPNFYGQNFSTTSIAYKMIYENEKEGQTPPVTEEKYIYNDLQIAI
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEEEEECCCCCCCCCCCCCCCEEEEEEEEEE
TGNVKIEEKPFEFKTTNSANLAPTYLQISKMFNDGKKDILNYLYKNNIESGNVEYQFSYV
ECCEEEECCCCEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEE
NLTNDYSGDVKSDGKTEFKLISEEQTIAERKTGQINGIAIAPPDRHFKNGAQKFGYTFVE
EECCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCEEEECCCCHHHHCHHHHHCEEEEE
TNQSFSLLVGIGKFFTGDFSAISGPVGIAKSSIGTTGAATTSMVASRLFYVSSISANLFM
CCCCEEEEEEHHHHHCCCHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
LNMLPFPPLDGYKFETLVEVTRKEVSQKSKTIIYAAGAILLVTFIVIVTIKDFIV
EECCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSVMIVILSILISIIVVLVLITLHELGHFIVAKLSKAYVFEFAIGFGPKLFVIKTKETY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEEECCCE
SVRLIPLGGYVSIASDFAEPPKGREEEFEKIPDIRKIDYAIKKKTLFILFGPLMNLFIAY
EEEEEEECCHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHEEEEEEHHHHHHHHHHH
ILIFSVMFGVGYKPSDPNFYGQNFSTTSIAYKMIYENEKEGQTPPVTEEKYIYNDLQIAI
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEEEEECCCCCCCCCCCCCCCEEEEEEEEEE
TGNVKIEEKPFEFKTTNSANLAPTYLQISKMFNDGKKDILNYLYKNNIESGNVEYQFSYV
ECCEEEECCCCEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEE
NLTNDYSGDVKSDGKTEFKLISEEQTIAERKTGQINGIAIAPPDRHFKNGAQKFGYTFVE
EECCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCEEEECCCCHHHHCHHHHHCEEEEE
TNQSFSLLVGIGKFFTGDFSAISGPVGIAKSSIGTTGAATTSMVASRLFYVSSISANLFM
CCCCEEEEEEHHHHHCCCHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
LNMLPFPPLDGYKFETLVEVTRKEVSQKSKTIIYAAGAILLVTFIVIVTIKDFIV
EECCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]