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The map label for this gene is yajL [H]

Identifier: 50365079

GI number: 50365079

Start: 301819

End: 302364

Strand: Direct

Name: yajL [H]

Synonym: Mfl263

Alternate gene names: 50365079

Gene position: 301819-302364 (Clockwise)

Preceding gene: 50365078

Following gene: 50365080

Centisome position: 38.05

GC content: 24.18

Gene sequence:

>546_bases
ATGAAAAAAGTAGCAATAATTTTACATAAAAATTTTGAAGAATCAGAAGCTATTGTAACAATTGATATACTAAGAAGATC
TGAAATTATTGTAGATATATACAATATTGAAAATAAAGATTTTCAAGTAGGTTCTCATAATATAATTGTAAAAACAGAAT
ATAATATTCAATCGCTGAATTCACAAAATTATGATGGAATAGTTATACCTGGAGGACCAGGAGTAAATGAATTATTTGAT
AATGAAATTTTATTAAATTTAATAAAAGATTTTAATGATAAAAATAAAATGGTTAGTGCTATTTGCGCTGCACCACAAAT
TTTAGGTCTAGCTGGAATTATCGATGATATTAAAATAGTAAAATTCCCTACTTCTAATAAATACTTAGAAAAAGCTTTAG
TTCAAGAAAAAGATAGTATTATAGACAAAAATATTGTTACTGGTTCAAGCATCGGAACAGTAGTTCCATTTGCCTTAAAT
ATAATAGAATATCTACAAGGAAAAGAACAAAAAGAAAAAATTAGACAACAACTTGTAATTATTTAA

Upstream 100 bases:

>100_bases
GGATTATCTTTCTTTGGAAGTCTATCTGTTATAACTAGAAAAATAAGAAAAGGTGACCCTGCAGGATTATTAAGTGAAAC
TCATGAATAAAGGAGAAATT

Downstream 100 bases:

>100_bases
CAAAATCACCTTACTAATACAGTGAGGTGATTTTTTTGAAGTTAGTAAAACAAACCTCGTATCAAGATTGTGGTGTTGCA
TGCATAGCAATGATGATTAA

Product: putative intracellular protease/amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKKVAIILHKNFEESEAIVTIDILRRSEIIVDIYNIENKDFQVGSHNIIVKTEYNIQSLNSQNYDGIVIPGGPGVNELFD
NEILLNLIKDFNDKNKMVSAICAAPQILGLAGIIDDIKIVKFPTSNKYLEKALVQEKDSIIDKNIVTGSSIGTVVPFALN
IIEYLQGKEQKEKIRQQLVII

Sequences:

>Translated_181_residues
MKKVAIILHKNFEESEAIVTIDILRRSEIIVDIYNIENKDFQVGSHNIIVKTEYNIQSLNSQNYDGIVIPGGPGVNELFD
NEILLNLIKDFNDKNKMVSAICAAPQILGLAGIIDDIKIVKFPTSNKYLEKALVQEKDSIIDKNIVTGSSIGTVVPFALN
IIEYLQGKEQKEKIRQQLVII
>Mature_181_residues
MKKVAIILHKNFEESEAIVTIDILRRSEIIVDIYNIENKDFQVGSHNIIVKTEYNIQSLNSQNYDGIVIPGGPGVNELFD
NEILLNLIKDFNDKNKMVSAICAAPQILGLAGIIDDIKIVKFPTSNKYLEKALVQEKDSIIDKNIVTGSSIGTVVPFALN
IIEYLQGKEQKEKIRQQLVII

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=184, Percent_Identity=27.1739130434783, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI31543380, Length=184, Percent_Identity=27.1739130434783, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI87081736, Length=185, Percent_Identity=29.1891891891892, Blast_Score=75, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17558714, Length=182, Percent_Identity=28.021978021978, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17531319, Length=168, Percent_Identity=27.3809523809524, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571932, Length=182, Percent_Identity=27.4725274725275, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653499, Length=182, Percent_Identity=27.4725274725275, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20295; Mature: 20295

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVAIILHKNFEESEAIVTIDILRRSEIIVDIYNIENKDFQVGSHNIIVKTEYNIQSLN
CCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEECCCEEEEEEECCHHHCC
SQNYDGIVIPGGPGVNELFDNEILLNLIKDFNDKNKMVSAICAAPQILGLAGIIDDIKIV
CCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
KFPTSNKYLEKALVQEKDSIIDKNIVTGSSIGTVVPFALNIIEYLQGKEQKEKIRQQLVI
EECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
I
C
>Mature Secondary Structure
MKKVAIILHKNFEESEAIVTIDILRRSEIIVDIYNIENKDFQVGSHNIIVKTEYNIQSLN
CCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEECCCEEEEEEECCHHHCC
SQNYDGIVIPGGPGVNELFDNEILLNLIKDFNDKNKMVSAICAAPQILGLAGIIDDIKIV
CCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
KFPTSNKYLEKALVQEKDSIIDKNIVTGSSIGTVVPFALNIIEYLQGKEQKEKIRQQLVI
EECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]