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The map label for this gene is pepO [H]

Identifier: 50365057

GI number: 50365057

Start: 267761

End: 269659

Strand: Direct

Name: pepO [H]

Synonym: Mfl241

Alternate gene names: 50365057

Gene position: 267761-269659 (Clockwise)

Preceding gene: 50365056

Following gene: 50365058

Centisome position: 33.76

GC content: 27.17

Gene sequence:

>1899_bases
ATGACAAAAATTAGACCACAAGATAATTTCTATGATTCAGTAAATAAAGAATGAATAGATAATAATGAATTACCAGATGG
ATATGCATCATGAGGAAGTTTTGAAATGCTTCAAAAAAAATCAACAGACGATATTAAAGCAATTATTAACGAACTTGTTA
ATGCAACTAAATTAGACAGAGATAGCAAAATGATAGCTAACCTTAGATCAAATTATTTAAATGATAAAGCAAGAAATAAA
CAAGGCATAAAACCTATTCAACCAATTTTAAATAAAATAAGTGCCTTAACTGATAAAAAAGAACTGACAAGTTTATTTGT
TGATTTATTCCAAGAGTGAGGGATTTCTTTCTTCCACTCAAAAGGCGTAGATTCAGATTTTAAAGATAGCAATTTAAGAG
CTTTAATGATTGATTCAATGGGTTTAGGAATGTCAGATAGAGATTTCTATGAAGAAACTCACCCAAGACATGAAGAAATT
AAAAATGCTTATAAAAATTACATTGAAAACTTAGTAAAGCTTTCAGGTGTAAGATTAAATACAAAAGATATTTTTAATTT
AATTTATAGTTTTGAGGAAAAAATATCAAAATCAATGTTTAAACAAGAAGAATTACGTGAACCTGAAAATATTTATAATG
TAGTAACTATTAAAGAATTAAACGATATATGTCCGATTGTTGATTGAACAGAATATCTAAATAAAACTGGTTATGACAAA
GCATCAAAAATTATTTTAACTGAACCTAAATATTTTGAAAAACTAAATCAAATGATTGAAGAAATAAGTTTAGATGATTT
AAAAGATATTATGTCATATAAAGTTACTAGTTCTTACTCAAGAATGTTAACAATTGATTTATATGAAAATAGCTTCAAGT
ATGGATCAGTATTTAGCGGTGTTAAAAAAATGAAACCAATTGAAGATAGAGTAGTTGAATTTGTTGATGGTACTCTTGGA
GAATTAATTTCAAAAGAATATGTAAAACGTCATTTTTCTGAAGATGCTAAAAAAGATGTTTTAAAAATGGTTAATGATCT
ATTGAAAGTATATGAAAATAGAATTAATACATTAGATTGAATGTCAGATGAAACAAAAACAAAAGCTATTGAAAAATTAA
ATTCATTCACTATTAAAATTGGTTATCCTGACAAATGAGAAGATTTAAGTGATGTTGAAATCCTTAGTTATGAAGAAGGC
GGAAGTTTATTCGATAATATGCAAAGTTTAGCTAAACATTATATTAAAAAAGAGCTAAAAGAAATTAATTTACCTGTTGA
TAAAACAAAATGATATATGGATGCACAAACTGTAAATGCATATTACAATCCAACATCAAATGAAATCTGTTTCCCTGCTG
GGATTTTACAAAAACCATTTTATGATGTAAATCAATCTCATGCTGCTAACCTTGGTGGAATTGGTGCTGTTATTGGACAT
GAAGTTAGTCATGGTTTTGATGATGAAGGAAGTAAATTTGATAAAGATGGAAACTTTGAAAACTGATGAACTGAAACAGA
CAATGAACAATACAAATTAAGAACTCAAAGAGTTGTTGATCAATATAACGAATATCAAATTAATGGTTCGAATGTTAATG
GTAAATTAACACTTGGTGAAAACATTGGTGATTTAAGTGGAGTTGCTGCTGCTTTAGATATATGTAAAGCACAAAGTCCA
AATGATTTAAAAGACTTCTTTACAAACTATGCTTTAGTATGAAGAAGAAAAGCAACTGATGAACAAAAAAACACAAGACT
ATTAGTTGATCCTCATTCACCTGAAGAATTCAGATGTAATGGTGTATTAGTAAACATAAATGAATTCCATGAAGTTTATG
AAACTAAACCTGGTGATGGAATGTATAAACCAGAAGAAGAAAGAACTAAAGTTTGATAA

Upstream 100 bases:

>100_bases
ACAATTGGATAAAGTTAAGACAATTAAAAAATAAAAACAAATCACTTTTTAAAAGTGATTTTTTTGTTATAAAATAATAA
CTAATAAAAGGAGAGATTAT

Downstream 100 bases:

>100_bases
TAAACTATTTAAACCGTCTTTAAGATGGTTTTTTTCTTGTTTTAACTTATAATTTTATATAGAAGCAAGAGGTTTAATAA
TGCAAAAAGAAGTAAATATT

Product: putative membrane metallo endopeptidase

Products: NA

Alternate protein names: Endopeptidase O [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MTKIRPQDNFYDSVNKEWIDNNELPDGYASWGSFEMLQKKSTDDIKAIINELVNATKLDRDSKMIANLRSNYLNDKARNK
QGIKPIQPILNKISALTDKKELTSLFVDLFQEWGISFFHSKGVDSDFKDSNLRALMIDSMGLGMSDRDFYEETHPRHEEI
KNAYKNYIENLVKLSGVRLNTKDIFNLIYSFEEKISKSMFKQEELREPENIYNVVTIKELNDICPIVDWTEYLNKTGYDK
ASKIILTEPKYFEKLNQMIEEISLDDLKDIMSYKVTSSYSRMLTIDLYENSFKYGSVFSGVKKMKPIEDRVVEFVDGTLG
ELISKEYVKRHFSEDAKKDVLKMVNDLLKVYENRINTLDWMSDETKTKAIEKLNSFTIKIGYPDKWEDLSDVEILSYEEG
GSLFDNMQSLAKHYIKKELKEINLPVDKTKWYMDAQTVNAYYNPTSNEICFPAGILQKPFYDVNQSHAANLGGIGAVIGH
EVSHGFDDEGSKFDKDGNFENWWTETDNEQYKLRTQRVVDQYNEYQINGSNVNGKLTLGENIGDLSGVAAALDICKAQSP
NDLKDFFTNYALVWRRKATDEQKNTRLLVDPHSPEEFRCNGVLVNINEFHEVYETKPGDGMYKPEEERTKVW

Sequences:

>Translated_632_residues
MTKIRPQDNFYDSVNKE*IDNNELPDGYAS*GSFEMLQKKSTDDIKAIINELVNATKLDRDSKMIANLRSNYLNDKARNK
QGIKPIQPILNKISALTDKKELTSLFVDLFQE*GISFFHSKGVDSDFKDSNLRALMIDSMGLGMSDRDFYEETHPRHEEI
KNAYKNYIENLVKLSGVRLNTKDIFNLIYSFEEKISKSMFKQEELREPENIYNVVTIKELNDICPIVD*TEYLNKTGYDK
ASKIILTEPKYFEKLNQMIEEISLDDLKDIMSYKVTSSYSRMLTIDLYENSFKYGSVFSGVKKMKPIEDRVVEFVDGTLG
ELISKEYVKRHFSEDAKKDVLKMVNDLLKVYENRINTLD*MSDETKTKAIEKLNSFTIKIGYPDK*EDLSDVEILSYEEG
GSLFDNMQSLAKHYIKKELKEINLPVDKTK*YMDAQTVNAYYNPTSNEICFPAGILQKPFYDVNQSHAANLGGIGAVIGH
EVSHGFDDEGSKFDKDGNFEN**TETDNEQYKLRTQRVVDQYNEYQINGSNVNGKLTLGENIGDLSGVAAALDICKAQSP
NDLKDFFTNYALV*RRKATDEQKNTRLLVDPHSPEEFRCNGVLVNINEFHEVYETKPGDGMYKPEEERTKV*
>Mature_631_residues
TKIRPQDNFYDSVNKE*IDNNELPDGYAS*GSFEMLQKKSTDDIKAIINELVNATKLDRDSKMIANLRSNYLNDKARNKQ
GIKPIQPILNKISALTDKKELTSLFVDLFQE*GISFFHSKGVDSDFKDSNLRALMIDSMGLGMSDRDFYEETHPRHEEIK
NAYKNYIENLVKLSGVRLNTKDIFNLIYSFEEKISKSMFKQEELREPENIYNVVTIKELNDICPIVD*TEYLNKTGYDKA
SKIILTEPKYFEKLNQMIEEISLDDLKDIMSYKVTSSYSRMLTIDLYENSFKYGSVFSGVKKMKPIEDRVVEFVDGTLGE
LISKEYVKRHFSEDAKKDVLKMVNDLLKVYENRINTLD*MSDETKTKAIEKLNSFTIKIGYPDK*EDLSDVEILSYEEGG
SLFDNMQSLAKHYIKKELKEINLPVDKTK*YMDAQTVNAYYNPTSNEICFPAGILQKPFYDVNQSHAANLGGIGAVIGHE
VSHGFDDEGSKFDKDGNFEN**TETDNEQYKLRTQRVVDQYNEYQINGSNVNGKLTLGENIGDLSGVAAALDICKAQSPN
DLKDFFTNYALV*RRKATDEQKNTRLLVDPHSPEEFRCNGVLVNINEFHEVYETKPGDGMYKPEEERTKV*

Specific function: Unknown

COG id: COG3590

COG function: function code O; Predicted metalloendopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M13 family [H]

Homologues:

Organism=Homo sapiens, GI164519138, Length=662, Percent_Identity=29.7583081570997, Blast_Score=251, Evalue=2e-66,
Organism=Homo sapiens, GI164519136, Length=662, Percent_Identity=29.7583081570997, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI164519140, Length=662, Percent_Identity=29.7583081570997, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI4503443, Length=662, Percent_Identity=29.7583081570997, Blast_Score=250, Evalue=3e-66,
Organism=Homo sapiens, GI82617560, Length=652, Percent_Identity=28.9877300613497, Blast_Score=232, Evalue=9e-61,
Organism=Homo sapiens, GI153945771, Length=652, Percent_Identity=28.9877300613497, Blast_Score=232, Evalue=1e-60,
Organism=Homo sapiens, GI153945836, Length=652, Percent_Identity=28.9877300613497, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI153945761, Length=652, Percent_Identity=28.9877300613497, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI90403592, Length=678, Percent_Identity=26.6961651917404, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI116256333, Length=558, Percent_Identity=29.2114695340502, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI116256331, Length=558, Percent_Identity=29.2114695340502, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI116256329, Length=558, Percent_Identity=29.2114695340502, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI116256327, Length=558, Percent_Identity=29.2114695340502, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI157426891, Length=524, Percent_Identity=26.7175572519084, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI239049391, Length=684, Percent_Identity=25, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI4557691, Length=494, Percent_Identity=21.6599190283401, Blast_Score=102, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI86562497, Length=663, Percent_Identity=28.5067873303167, Blast_Score=241, Evalue=7e-64,
Organism=Caenorhabditis elegans, GI17533333, Length=660, Percent_Identity=27.8787878787879, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI32563993, Length=584, Percent_Identity=28.0821917808219, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI25148650, Length=549, Percent_Identity=27.5045537340619, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17564342, Length=456, Percent_Identity=27.4122807017544, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI71987442, Length=587, Percent_Identity=26.9165247018739, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17534401, Length=340, Percent_Identity=29.1176470588235, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17570047, Length=599, Percent_Identity=24.0400667779633, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17533319, Length=342, Percent_Identity=27.1929824561404, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994787, Length=316, Percent_Identity=27.8481012658228, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17532485, Length=395, Percent_Identity=25.3164556962025, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71998977, Length=476, Percent_Identity=25, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71998975, Length=476, Percent_Identity=25, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193204436, Length=303, Percent_Identity=25.4125412541254, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17534885, Length=283, Percent_Identity=27.208480565371, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71988640, Length=337, Percent_Identity=23.1454005934718, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71986886, Length=294, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643425, Length=665, Percent_Identity=29.0225563909774, Blast_Score=251, Evalue=9e-67,
Organism=Drosophila melanogaster, GI45551938, Length=610, Percent_Identity=26.3934426229508, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI45550777, Length=610, Percent_Identity=26.3934426229508, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24640050, Length=530, Percent_Identity=27.1698113207547, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24640052, Length=530, Percent_Identity=27.1698113207547, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI17737761, Length=658, Percent_Identity=25.8358662613982, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24650487, Length=376, Percent_Identity=27.3936170212766, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI221474862, Length=315, Percent_Identity=28.8888888888889, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24650765, Length=376, Percent_Identity=26.8617021276596, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21355943, Length=329, Percent_Identity=27.355623100304, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24650885, Length=328, Percent_Identity=27.1341463414634, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24641622, Length=457, Percent_Identity=22.1006564551422, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24650889, Length=545, Percent_Identity=22.2018348623853, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281362760, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000718
- InterPro:   IPR018497
- InterPro:   IPR008753 [H]

Pfam domain/function: PF01431 Peptidase_M13; PF05649 Peptidase_M13_N [H]

EC number: NA

Molecular weight: Translated: 71000; Mature: 70869

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIRPQDNFYDSVNKEIDNNELPDGYASGSFEMLQKKSTDDIKAIINELVNATKLDRDS
CCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCHH
KMIANLRSNYLNDKARNKQGIKPIQPILNKISALTDKKELTSLFVDLFQEGISFFHSKGV
HHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DSDFKDSNLRALMIDSMGLGMSDRDFYEETHPRHEEIKNAYKNYIENLVKLSGVRLNTKD
CCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IFNLIYSFEEKISKSMFKQEELREPENIYNVVTIKELNDICPIVDTEYLNKTGYDKASKI
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEHHHHCCCCCCCHHHHCCCCCCCCCEE
ILTEPKYFEKLNQMIEEISLDDLKDIMSYKVTSSYSRMLTIDLYENSFKYGSVFSGVKKM
EEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHC
KPIEDRVVEFVDGTLGELISKEYVKRHFSEDAKKDVLKMVNDLLKVYENRINTLDMSDET
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
KTKAIEKLNSFTIKIGYPDKEDLSDVEILSYEEGGSLFDNMQSLAKHYIKKELKEINLPV
HHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DKTKYMDAQTVNAYYNPTSNEICFPAGILQKPFYDVNQSHAANLGGIGAVIGHEVSHGFD
CHHHCCCCHHEEEEECCCCCCEECCHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHCCCC
DEGSKFDKDGNFENTETDNEQYKLRTQRVVDQYNEYQINGSNVNGKLTLGENIGDLSGVA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEECCCCCCEEEEECCCCCHHHHHH
AALDICKAQSPNDLKDFFTNYALVRRKATDEQKNTRLLVDPHSPEEFRCNGVLVNINEFH
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEECCEEEEHHHHH
EVYETKPGDGMYKPEEERTKV
HHHHCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
TKIRPQDNFYDSVNKEIDNNELPDGYASGSFEMLQKKSTDDIKAIINELVNATKLDRDS
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCHH
KMIANLRSNYLNDKARNKQGIKPIQPILNKISALTDKKELTSLFVDLFQEGISFFHSKGV
HHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DSDFKDSNLRALMIDSMGLGMSDRDFYEETHPRHEEIKNAYKNYIENLVKLSGVRLNTKD
CCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IFNLIYSFEEKISKSMFKQEELREPENIYNVVTIKELNDICPIVDTEYLNKTGYDKASKI
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEHHHHCCCCCCCHHHHCCCCCCCCCEE
ILTEPKYFEKLNQMIEEISLDDLKDIMSYKVTSSYSRMLTIDLYENSFKYGSVFSGVKKM
EEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHC
KPIEDRVVEFVDGTLGELISKEYVKRHFSEDAKKDVLKMVNDLLKVYENRINTLDMSDET
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
KTKAIEKLNSFTIKIGYPDKEDLSDVEILSYEEGGSLFDNMQSLAKHYIKKELKEINLPV
HHHHHHHHCCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DKTKYMDAQTVNAYYNPTSNEICFPAGILQKPFYDVNQSHAANLGGIGAVIGHEVSHGFD
CHHHCCCCHHEEEEECCCCCCEECCHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHCCCC
DEGSKFDKDGNFENTETDNEQYKLRTQRVVDQYNEYQINGSNVNGKLTLGENIGDLSGVA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEECCCCCCEEEEECCCCCHHHHHH
AALDICKAQSPNDLKDFFTNYALVRRKATDEQKNTRLLVDPHSPEEFRCNGVLVNINEFH
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEECCEEEEHHHHH
EVYETKPGDGMYKPEEERTKV
HHHHCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9726890 [H]