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The map label for this gene is oxaA1 [H]

Identifier: 49188323

GI number: 49188323

Start: 5227129

End: 5227896

Strand: Reverse

Name: oxaA1 [H]

Synonym: BAS5339

Alternate gene names: 49188323

Gene position: 5227896-5227129 (Counterclockwise)

Preceding gene: 49188324

Following gene: 49188322

Centisome position: 99.99

GC content: 36.85

Gene sequence:

>768_bases
TTGAAAAAGAAATTAGGTTTACTAGCCATGGTTGTTGCATTAATGGCGATTACTGCTGGCTGTAGTGAAGTAAATCAGCC
AATTACACCAAAGAGCACTGGAATTTGGAATGAATACTTCGTATACCCGCTTTCTCAGTTAATTACGTATTTTGCCAACT
TATTTGGTAGTAATTACGGTTTAGCAATCGTTGTTACGACTCTTATTATTCGTTTTGCATTATTACCATTAATGATTAAA
CAAACGAAGAGTACGAAAGCAATGCAAGCGTTACAACCAGAAATGGTGAAGTTAAAAGAGAAATATAGCTCTAAAGATCA
AGCAACACAGCAAAAACTACAACAAGAAATGATGCAGTTATATCAAAAAAATGGTGTAAATCCATTAGCAGGATGTTTAC
CAATCTTTGTTCAGATGCCTATTTTATTCGCGTTTTACCATGCGATTATGAGAACATCAGAAATTAGTAAGCATACATTC
TTATGGTTCGACTTAGGACAGGCAGATCCGTACTATATCTTACCGGTTGTTGCGGCAATTACGACATTTATTCAGCAAAA
ACTTGCAATGGCAGGAACTGCTGGTCAAAATCCGCAAATGGCAATGATGCTTTGGTTAATGCCAATCATGATTTTAATCT
TTGCAATTAACTTCCCAGCTGCCTTATCACTTTACTGGGTTGTTGGTAATATCTTTGGTATCGCTCAAATGTACTTGATC
AAAGGGCCGGAAATTAAGGCTAGTAAGGCAGGAGGATCAAGCAAGTGA

Upstream 100 bases:

>100_bases
CTTAATTCATGTCTTTAAACGCTCTGGTATGAAAAGAATAAAAAGTAGCGTAAGGAAATGAATTACACTATATACATACC
GATACAAGGAGGAGTAGGCT

Downstream 100 bases:

>100_bases
GTATAATTACTGCTAAAGGACAAACAGTCGAGCTGGCAGTACAGGATGCTTTAAGGCAACTAAATGTTTCAAAAGACCGA
GTAGATATAAGTATTATCGA

Product: OxaA-like protein precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKKKLGLLAMVVALMAITAGCSEVNQPITPKSTGIWNEYFVYPLSQLITYFANLFGSNYGLAIVVTTLIIRFALLPLMIK
QTKSTKAMQALQPEMVKLKEKYSSKDQATQQKLQQEMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTSEISKHTF
LWFDLGQADPYYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFGIAQMYLI
KGPEIKASKAGGSSK

Sequences:

>Translated_255_residues
MKKKLGLLAMVVALMAITAGCSEVNQPITPKSTGIWNEYFVYPLSQLITYFANLFGSNYGLAIVVTTLIIRFALLPLMIK
QTKSTKAMQALQPEMVKLKEKYSSKDQATQQKLQQEMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTSEISKHTF
LWFDLGQADPYYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFGIAQMYLI
KGPEIKASKAGGSSK
>Mature_255_residues
MKKKLGLLAMVVALMAITAGCSEVNQPITPKSTGIWNEYFVYPLSQLITYFANLFGSNYGLAIVVTTLIIRFALLPLMIK
QTKSTKAMQALQPEMVKLKEKYSSKDQATQQKLQQEMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTSEISKHTF
LWFDLGQADPYYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFGIAQMYLI
KGPEIKASKAGGSSK

Specific function: Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes [H]

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI223718097, Length=200, Percent_Identity=26.5, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790140, Length=215, Percent_Identity=35.8139534883721, Blast_Score=135, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24662345, Length=197, Percent_Identity=26.9035532994924, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356443, Length=197, Percent_Identity=26.9035532994924, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001708
- InterPro:   IPR023060 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 28425; Mature: 28425

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]