Click here to switch to the map view.

The map label for this gene is yhcY [H]

Identifier: 49188250

GI number: 49188250

Start: 5146905

End: 5147879

Strand: Reverse

Name: yhcY [H]

Synonym: BAS5265

Alternate gene names: 49188250

Gene position: 5147879-5146905 (Counterclockwise)

Preceding gene: 49188252

Following gene: 49188249

Centisome position: 98.45

GC content: 33.03

Gene sequence:

>975_bases
ATGTTTCAAGAGAATCGTACAAATGAATTAGTTATATTAAAAGAAATTGCAGAAACGCTAAATACATCAAATGATACATA
TCATGTATTGCAAGCAGTGCTAGAAAAATTACTTAGTGTAACAGGTTTAACGACAGGATGGATATTTCTTGCGGATGAAA
ATGGTAGATATACAAAATTAATTGATTATCAATTACCAGAGGCACTTACATATGAAAATAAACGCCCGATGTGTGAAGGG
GAATGTTGGTGTTTACGTGGCTTTGTGGATGGAAAGTTAGAGAGAGCTGTTAATATTATTGAATGTAAAAGAATTAATAA
TGCAATTGAATATAATTGGGGAGATACAGAAGGGATTCTTCATCATGCTACGGTTCCTTTAAAGGCTGGAGGAGAAAAAT
TTGGTTTGTTAAATGTGGCAAGCCCAGGTAAAACACATTTTTCAGAAGAAGAATTAGTATTGCTTCAATCAGTTGCTTTC
CAAATTGGAACGGCTTTAAAACGAGCAAAGTTATATGAAAATGAAAAGCGAAGAGCGCATTATTATGTGAAATTAGAACG
TTTCATTCAAGTTTTAAGAACGATTCATCAATTTAATATATTGCCTGAAAAAGTTGTAAATCAATTAGGTGAAGTGTTTC
AGTGGAATCAAGTGGCGTTTTTTATTAGGGAAGAGAAAGAATTATCTTTGCGGGCATCTTATTGCCAGGAAGAATTGCAC
GAGGATATAAAAGAAGCAGCGAAAGAAGCATTAGAAAAAGGTGAACTTATTTTATTAAACGATCAAATCAGTCATAAGGC
AGCCTCTAATAGAACGGTTATTGCCACACCAATACAGATTCAAACTCACATATTTGGTGTTTTATGTGTTAGTTCAAATC
ATGGTGAATTTGATGTGAATACGATAGATGTACTTCAAGCAATAACAAATCATATTTCCTTCGTGATAGAAAATTTAAGG
TTAAATGAGCAATGA

Upstream 100 bases:

>100_bases
ATGTTTTCACCATTATATCAATGTTATGAATAAGTACAAAGTGAAAAGTAGATGATTTATGTTAGGAACTATGTAAAATC
TTGTATGTAGGAGACGAATT

Downstream 100 bases:

>100_bases
CGCGAACTTGTACGAATGGAAGAAAGAAATCGGTTAGCAAGGGACTTACATGATTCCGTCTCACAAAAGCTATTTTCGTT
AACCTTTATGACAAAGGGCG

Product: cGMP-specific and -stimulated phosphodiesterase/adenylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKLIDYQLPEALTYENKRPMCEG
ECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGILHHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAF
QIGTALKRAKLYENEKRRAHYYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVAFFIREEKELSLRASYCQEELH
EDIKEAAKEALEKGELILLNDQISHKAASNRTVIATPIQIQTHIFGVLCVSSNHGEFDVNTIDVLQAITNHISFVIENLR
LNEQ

Sequences:

>Translated_324_residues
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKLIDYQLPEALTYENKRPMCEG
ECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGILHHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAF
QIGTALKRAKLYENEKRRAHYYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVAFFIREEKELSLRASYCQEELH
EDIKEAAKEALEKGELILLNDQISHKAASNRTVIATPIQIQTHIFGVLCVSSNHGEFDVNTIDVLQAITNHISFVIENLR
LNEQ
>Mature_324_residues
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKLIDYQLPEALTYENKRPMCEG
ECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGILHHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAF
QIGTALKRAKLYENEKRRAHYYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVAFFIREEKELSLRASYCQEELH
EDIKEAAKEALEKGELILLNDQISHKAASNRTVIATPIQIQTHIFGVLCVSSNHGEFDVNTIDVLQAITNHISFVIENLR
LNEQ

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG2203

COG function: function code T; FOG: GAF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37097; Mature: 37097

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKL
CCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEE
IDYQLPEALTYENKRPMCEGECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGIL
EECCCCHHHCCCCCCCCCCCCEEEEECHHCHHHHHHHHHHHHHHCCCCEEECCCCCCCEE
HHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAFQIGTALKRAKLYENEKRRAH
EEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
YYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVAFFIREEKELSLRASYCQEELH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHH
EDIKEAAKEALEKGELILLNDQISHKAASNRTVIATPIQIQTHIFGVLCVSSNHGEFDVN
HHHHHHHHHHHHCCCEEEEECCHHHHHCCCCEEEEECEEEEEEEEEEEEEECCCCCCCCH
TIDVLQAITNHISFVIENLRLNEQ
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKL
CCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEE
IDYQLPEALTYENKRPMCEGECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGIL
EECCCCHHHCCCCCCCCCCCCEEEEECHHCHHHHHHHHHHHHHHCCCCEEECCCCCCCEE
HHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAFQIGTALKRAKLYENEKRRAH
EEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
YYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVAFFIREEKELSLRASYCQEELH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHH
EDIKEAAKEALEKGELILLNDQISHKAASNRTVIATPIQIQTHIFGVLCVSSNHGEFDVN
HHHHHHHHHHHHCCCEEEEECCHHHHHCCCCEEEEECEEEEEEEEEEEEEECCCCCCCCH
TIDVLQAITNHISFVIENLRLNEQ
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]