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The map label for this gene is yhcY [H]

Identifier: 49188249

GI number: 49188249

Start: 5146308

End: 5146889

Strand: Reverse

Name: yhcY [H]

Synonym: BAS5264

Alternate gene names: 49188249

Gene position: 5146889-5146308 (Counterclockwise)

Preceding gene: 49188250

Following gene: 49188248

Centisome position: 98.44

GC content: 38.66

Gene sequence:

>582_bases
ATGGAAGAAAGAAATCGGTTAGCAAGGGACTTACATGATTCCGTCTCACAAAAGCTATTTTCGTTAACCTTTATGACAAA
GGGCGCTGAGGCAGTCTTAAAAGGTCAAAATGAAAAGGTGGACCGATCTTTGCATGAGATGCGTGAACTAGCGCAAGGAT
CTTTAAAAGAAATGAGGACGTTGATTTGGCAACTACGTCCAGCAGGTTTAGAGAAAGGATTATTACCAGCTTTAAAGCAA
TATGGTGAAAGTTTGGGGCTGAAAATTCGGGAACAAGTTACAGGTGTCCGAGATTTACCGCGCGTAGTAGAGGAAGCGTT
ATGGAGAATTGGACAAGAAGCTTTAAATAACGTAAGTAAGCATGCGAATGTTAGAGAAGCGACGATTTATTTCAAAGTGA
CCGAGAAGAATGTATCATTAGAAATAGTCGATCAAGGAAACGGCTTTGTAGAAAAGAATATAAAAGAGAAGAAATCACTT
GGCATGACTACGATGCGCGAAAGAGTAGAATTAGTCGGTGGAACAATTAAAATTGTAAGTGATAAAAAAAGAACAAGTGT
AAAAGTAAACGTACCATTATGA

Upstream 100 bases:

>100_bases
TGATGTGAATACGATAGATGTACTTCAAGCAATAACAAATCATATTTCCTTCGTGATAGAAAATTTAAGGTTAAATGAGC
AATGACGCGAACTTGTACGA

Downstream 100 bases:

>100_bases
TGTGAAAATGAGGGAAGTTTGTGAAAATAAAAGTATTATTAGTTGATGATCATACAGTCGTTTTAAAAGGATTAGCATTT
TTCTTAAGTACACAGGAAGA

Product: two-component sensor protein, C-terminus

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MEERNRLARDLHDSVSQKLFSLTFMTKGAEAVLKGQNEKVDRSLHEMRELAQGSLKEMRTLIWQLRPAGLEKGLLPALKQ
YGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFVEKNIKEKKSL
GMTTMRERVELVGGTIKIVSDKKRTSVKVNVPL

Sequences:

>Translated_193_residues
MEERNRLARDLHDSVSQKLFSLTFMTKGAEAVLKGQNEKVDRSLHEMRELAQGSLKEMRTLIWQLRPAGLEKGLLPALKQ
YGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFVEKNIKEKKSL
GMTTMRERVELVGGTIKIVSDKKRTSVKVNVPL
>Mature_193_residues
MEERNRLARDLHDSVSQKLFSLTFMTKGAEAVLKGQNEKVDRSLHEMRELAQGSLKEMRTLIWQLRPAGLEKGLLPALKQ
YGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFVEKNIKEKKSL
GMTTMRERVELVGGTIKIVSDKKRTSVKVNVPL

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 21866; Mature: 21866

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERNRLARDLHDSVSQKLFSLTFMTKGAEAVLKGQNEKVDRSLHEMRELAQGSLKEMRT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIWQLRPAGLEKGLLPALKQYGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSK
HHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
HANVREATIYFKVTEKNVSLEIVDQGNGFVEKNIKEKKSLGMTTMRERVELVGGTIKIVS
HCCCEEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEE
DKKRTSVKVNVPL
CCCCCEEEEECCC
>Mature Secondary Structure
MEERNRLARDLHDSVSQKLFSLTFMTKGAEAVLKGQNEKVDRSLHEMRELAQGSLKEMRT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIWQLRPAGLEKGLLPALKQYGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSK
HHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
HANVREATIYFKVTEKNVSLEIVDQGNGFVEKNIKEKKSLGMTTMRERVELVGGTIKIVS
HCCCEEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEE
DKKRTSVKVNVPL
CCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]