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The map label for this gene is yhcZ [H]

Identifier: 49188248

GI number: 49188248

Start: 5145640

End: 5146287

Strand: Reverse

Name: yhcZ [H]

Synonym: BAS5263

Alternate gene names: 49188248

Gene position: 5146287-5145640 (Counterclockwise)

Preceding gene: 49188249

Following gene: 49188247

Centisome position: 98.42

GC content: 36.57

Gene sequence:

>648_bases
GTGAAAATAAAAGTATTATTAGTTGATGATCATACAGTCGTTTTAAAAGGATTAGCATTTTTCTTAAGTACACAGGAAGA
TATAGAGTTAGTGGGAGAAGCAAGTAATGGGAAAGAGGCACTAGTGAAAGTAGGAGAGACAAATCCTGATGTTGTACTAA
TGGATTTATATATGCCCGAAATGGATGGTGTTGAAGCGACAGCGTGTATTAAAAAAGAATATCCGGATGTGAAAGTAATT
GTATTGACTAGCTTTTCTGATCAGGCGCATGTGTTACCAGCATTAAGGGCTGGAGCAAGCGGGTATATTTTAAAAGATGT
AGAACCGGATCAGCTTGTTGAAGCTATTCGAAGCGCATATAAAGGTAATATTCAATTACATCCAGATATAGCAAATGCTC
TTCTCTCCCAAACGTTACCTGTGGAAGAAAAGGAAGAAGAGCCTTCTATTCAAGTAGATGTGCTAACAGCGAGAGAAAAT
GAAGTATTGCAGCTATTAGCGAAAGGGATGAGTAATAAAGAAATCGCTTCTGTTTTAGTTATTACAGAAAAAACAGTAAA
AGCTCATGTAAGTAGTATTTTGAGTAAGTTGCATTTATCTGATCGCACGCAAGCGGCATTATATGCAGTGAAAAACGGAA
TTGTATAA

Upstream 100 bases:

>100_bases
GAGTAGAATTAGTCGGTGGAACAATTAAAATTGTAAGTGATAAAAAAAGAACAAGTGTAAAAGTAAACGTACCATTATGA
TGTGAAAATGAGGGAAGTTT

Downstream 100 bases:

>100_bases
GACAAAAGTCGTAAGACCTAGTTCGCCTTTAGAAGGTGGACTTTTTTTATGGAAAAATACGTCTATGTGAGGACGAAATT
GTCTCGATATGAAGATAAAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKIKVLLVDDHTVVLKGLAFFLSTQEDIELVGEASNGKEALVKVGETNPDVVLMDLYMPEMDGVEATACIKKEYPDVKVI
VLTSFSDQAHVLPALRAGASGYILKDVEPDQLVEAIRSAYKGNIQLHPDIANALLSQTLPVEEKEEEPSIQVDVLTAREN
EVLQLLAKGMSNKEIASVLVITEKTVKAHVSSILSKLHLSDRTQAALYAVKNGIV

Sequences:

>Translated_215_residues
MKIKVLLVDDHTVVLKGLAFFLSTQEDIELVGEASNGKEALVKVGETNPDVVLMDLYMPEMDGVEATACIKKEYPDVKVI
VLTSFSDQAHVLPALRAGASGYILKDVEPDQLVEAIRSAYKGNIQLHPDIANALLSQTLPVEEKEEEPSIQVDVLTAREN
EVLQLLAKGMSNKEIASVLVITEKTVKAHVSSILSKLHLSDRTQAALYAVKNGIV
>Mature_215_residues
MKIKVLLVDDHTVVLKGLAFFLSTQEDIELVGEASNGKEALVKVGETNPDVVLMDLYMPEMDGVEATACIKKEYPDVKVI
VLTSFSDQAHVLPALRAGASGYILKDVEPDQLVEAIRSAYKGNIQLHPDIANALLSQTLPVEEKEEEPSIQVDVLTAREN
EVLQLLAKGMSNKEIASVLVITEKTVKAHVSSILSKLHLSDRTQAALYAVKNGIV

Specific function: Member of the two-component regulatory system yhcY/yhcZ [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=217, Percent_Identity=39.63133640553, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1788521, Length=205, Percent_Identity=36.5853658536585, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787473, Length=208, Percent_Identity=36.5384615384615, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790102, Length=204, Percent_Identity=34.3137254901961, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=28.2926829268293, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788712, Length=212, Percent_Identity=23.5849056603774, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI87082052, Length=136, Percent_Identity=33.0882352941176, Blast_Score=71, Evalue=4e-14,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=36.9369369369369, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788546, Length=198, Percent_Identity=29.2929292929293, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1789937, Length=211, Percent_Identity=27.4881516587678, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23400; Mature: 23400

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKVLLVDDHTVVLKGLAFFLSTQEDIELVGEASNGKEALVKVGETNPDVVLMDLYMPE
CEEEEEEECCCHHHHHHHHHHHCCCCHHHEEECCCCCCEEEEEECCCCCCEEEEEEECCC
MDGVEATACIKKEYPDVKVIVLTSFSDQAHVLPALRAGASGYILKDVEPDQLVEAIRSAY
CCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHHHH
KGNIQLHPDIANALLSQTLPVEEKEEEPSIQVDVLTARENEVLQLLAKGMSNKEIASVLV
CCCEEECCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCEEEEE
ITEKTVKAHVSSILSKLHLSDRTQAALYAVKNGIV
EEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKIKVLLVDDHTVVLKGLAFFLSTQEDIELVGEASNGKEALVKVGETNPDVVLMDLYMPE
CEEEEEEECCCHHHHHHHHHHHCCCCHHHEEECCCCCCEEEEEECCCCCCEEEEEEECCC
MDGVEATACIKKEYPDVKVIVLTSFSDQAHVLPALRAGASGYILKDVEPDQLVEAIRSAY
CCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHCCCCCEEEECCCHHHHHHHHHHHH
KGNIQLHPDIANALLSQTLPVEEKEEEPSIQVDVLTARENEVLQLLAKGMSNKEIASVLV
CCCEEECCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCEEEEE
ITEKTVKAHVSSILSKLHLSDRTQAALYAVKNGIV
EEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]