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The map label for this gene is hemX [H]

Identifier: 49187357

GI number: 49187357

Start: 4273227

End: 4274060

Strand: Reverse

Name: hemX [H]

Synonym: BAS4362

Alternate gene names: 49187357

Gene position: 4274060-4273227 (Counterclockwise)

Preceding gene: 49187358

Following gene: 49187356

Centisome position: 81.74

GC content: 32.61

Gene sequence:

>834_bases
ATGAGTTTTTTAAATAACAGTATTATTTATCATATTGCAATTATTTTATATGCTTGTAGCATTAGTTTATATTTTATAGA
TTATTTCCAAAGTAACCGAAAGGCGAACCGATTTGCTTTTTGGTTACTTTCGATTGTATGGGTTCTGCATTCTATTTTTA
TGTTGCTTAGAGCTACAGATTCAGAAACGAACCCTCTTTTAACCTTATTATCAGGGATTTATTTTTATGTTTGGCTATTG
ATTACGATGTCTTTAGTCATTAATCGATTTATGAGGATTGACTTTTTAGTCTTTTTTACAAATGTTGTCGCATTTGGCGT
AAGCGCTTTTTCTATTTTTACACCGCTCGGAAAGATGTCGCCGGTACTTGCAGAGCAATTAGTTTCGGAGCTTGTATACG
TACATGTCGGTATGGCTATTATTTCTTATGCAACTTTTACTGTATCGTTCATTTTTTCTATTATGTATTTATTGCAATAT
CGCCTATTAAAAAAGAAAAAATGGAATGCGAGATTAAGAAGGTTAGGAAATTTACCGAAGCTAGAATCGATGTCTTACGG
ATTAAATTTATTTTCTGTTCCATTTTTCTTACTAGCTATTTTATTAGGATGCATATGGGGATATACAAAATTGGACAATT
TCCATTGGTATGATACGAAAGTAATCGGGTCTTTTGTCGTTCTATTTGTATATTGTGCGGGCCTATATTTACGAGCTGCA
GACGTGTTGCAAGGGAAGAAAATCGTGCAGTGGAACATTGGGGCATTTCTCGTAATGCTAATTAATATTTTTCTATTAAG
CAGTTTATCCAACTTCCACTTTTGGTATTTATAA

Upstream 100 bases:

>100_bases
ATTTAGAAATGGAAGACGTAGAGAGTCGTGCGGAAGAAGTAGAACATAAAAGAGTGTGGACACCATCCGTTCCATCTTTA
TAATTTGGAAGGATGATCGG

Downstream 100 bases:

>100_bases
TGAGGAGAGAAAATTATGCGCAAAATTATTGTAGGGTCACGAAAGAGTAAATTAGCATTAACGCAAACAAACTGGTTTAT
TGATCAGTTAAAAGCGCTAG

Product: hemX protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSFLNNSIIYHIAIILYACSISLYFIDYFQSNRKANRFAFWLLSIVWVLHSIFMLLRATDSETNPLLTLLSGIYFYVWLL
ITMSLVINRFMRIDFLVFFTNVVAFGVSAFSIFTPLGKMSPVLAEQLVSELVYVHVGMAIISYATFTVSFIFSIMYLLQY
RLLKKKKWNARLRRLGNLPKLESMSYGLNLFSVPFFLLAILLGCIWGYTKLDNFHWYDTKVIGSFVVLFVYCAGLYLRAA
DVLQGKKIVQWNIGAFLVMLINIFLLSSLSNFHFWYL

Sequences:

>Translated_277_residues
MSFLNNSIIYHIAIILYACSISLYFIDYFQSNRKANRFAFWLLSIVWVLHSIFMLLRATDSETNPLLTLLSGIYFYVWLL
ITMSLVINRFMRIDFLVFFTNVVAFGVSAFSIFTPLGKMSPVLAEQLVSELVYVHVGMAIISYATFTVSFIFSIMYLLQY
RLLKKKKWNARLRRLGNLPKLESMSYGLNLFSVPFFLLAILLGCIWGYTKLDNFHWYDTKVIGSFVVLFVYCAGLYLRAA
DVLQGKKIVQWNIGAFLVMLINIFLLSSLSNFHFWYL
>Mature_276_residues
SFLNNSIIYHIAIILYACSISLYFIDYFQSNRKANRFAFWLLSIVWVLHSIFMLLRATDSETNPLLTLLSGIYFYVWLLI
TMSLVINRFMRIDFLVFFTNVVAFGVSAFSIFTPLGKMSPVLAEQLVSELVYVHVGMAIISYATFTVSFIFSIMYLLQYR
LLKKKKWNARLRRLGNLPKLESMSYGLNLFSVPFFLLAILLGCIWGYTKLDNFHWYDTKVIGSFVVLFVYCAGLYLRAAD
VLQGKKIVQWNIGAFLVMLINIFLLSSLSNFHFWYL

Specific function: Required for hemL synthesis [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae U1620K [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 32196; Mature: 32065

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure 
SFLNNSIIYHIAIILYACSISLYFIDYFQSNRKANRFAFWLLSIVWVLHSIFMLLRATD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SETNPLLTLLSGIYFYVWLLITMSLVINRFMRIDFLVFFTNVVAFGVSAFSIFTPLGKMS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCC
PVLAEQLVSELVYVHVGMAIISYATFTVSFIFSIMYLLQYRLLKKKKWNARLRRLGNLPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LESMSYGLNLFSVPFFLLAILLGCIWGYTKLDNFHWYDTKVIGSFVVLFVYCAGLYLRAA
HHHHHHCCHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DVLQGKKIVQWNIGAFLVMLINIFLLSSLSNFHFWYL
HHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2110138; 8969504; 9384377 [H]