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The map label for this gene is hrcA

Identifier: 49187211

GI number: 49187211

Start: 4130571

End: 4131587

Strand: Reverse

Name: hrcA

Synonym: BAS4215

Alternate gene names: 49187211

Gene position: 4131587-4130571 (Counterclockwise)

Preceding gene: 49187212

Following gene: 49187210

Centisome position: 79.02

GC content: 36.38

Gene sequence:

>1017_bases
ATGCTTACGGAACGTCAGCTCTTAATTTTACAAACAATTATTGATGACTTTATTGGATCAGCGCAACCTGTTGGGTCGAG
GACGTTGGCGAAGAAAGATGAAATCACGTATAGTTCAGCTACTATTCGAAATGAAATGGCTGATTTAGAGGAACTAGGAT
TTATTGAGAAAACGCATAGTTCTTCAGGACGTGTTCCTTCTGAGAAAGGATATCGTTTTTATGTAGACCATCTGTTAGCG
CCGCAAAATTTACCGAACGATGAAATTGTACAAATTAAAGATTTGTTTGTTGAAAGAATTTTTGAAGCGGAAAAGATTGC
ACAGCAATCGGCTCAAATTTTATCAGAGCTTACGAATTATACGGCCATTGTTCTTGGACCGAAGTTAAGCACAAATAAAC
TTAAAAACGTACAAATTGTACCGCTTGATCGTCAAACTGCAGTCGCTATTATTGTAACGGATACAGGGCATGTACAAAGC
AAAACGATTACCGTTCCGGAATCTGTTGATTTATCAGATTTAGAAAAAATGGTTAATATTTTAAATGAAAAGCTATCGGG
CGTACCAATGTCAGAACTCCATAATAAGATCTTTAAGGAAATTGTTACGGTACTGCGTGGGTATGTTCATAATTACGATA
GTGCAATAAAAATGTTAGATGGTACATTTCAAGTTCCTTTATCGGAAAAGATATACTTTGGAGGAAAAGCAAATATGCTT
TCTCAGCCAGAGTTCCATGACATTCACAAAGTAAGGTCCTTACTGACGATGATTGATAACGAAGCTGAGTTTTATGATAT
TTTGCGTCATAAACAAGTAGGTATTCAAGTGAAAATTGGTAGGGAAAACTCTGCGACGGCCATGGAAGATTGTAGTTTGA
TTTCTGCAACATATTCGATTGGAGAAGAACAGCTTGGAACAATTGCTATTTTAGGTCCGACAAGAATGCAATACTCTCGG
GTAATTAGTTTGTTACAGTTATTTACGAGACAATTTACAGATGGACTTAAAAAGTAA

Upstream 100 bases:

>100_bases
ATTTCGTGACGTTTCCGTTGACAATTGAATGTCAATTTTGGTAAGTTATTAATAGATTTAGCACTCGAAGACAAAGAGTG
CTAACAGAGGTGATGATGAG

Downstream 100 bases:

>100_bases
ATGAGAGTAATACATTCGCTCAAGTGATGAACTTTTCATTGCTGTGTGTAATATATAATGCTTAGGTAATTGTGTTTAAC
ATGGTACCTAATACCTTTTA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITYSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLA
PQNLPNDEIVQIKDLFVERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQS
KTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANML
SQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSR
VISLLQLFTRQFTDGLKK

Sequences:

>Translated_338_residues
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITYSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLA
PQNLPNDEIVQIKDLFVERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQS
KTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANML
SQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSR
VISLLQLFTRQFTDGLKK
>Mature_338_residues
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITYSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLA
PQNLPNDEIVQIKDLFVERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQS
KTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANML
SQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSR
VISLLQLFTRQFTDGLKK

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_BACAA (C3P8M2)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868605.1
- EnsemblBacteria:   EBBACT00000128059
- GeneID:   7849548
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4560
- GeneTree:   EBGT00050000002539
- ProtClustDB:   PRK00082
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR023120
- InterPro:   IPR011991
- Gene3D:   G3DSA:3.30.390.60
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 37960; Mature: 37960

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITYSSATIRNEMADLEELGFIEKTHS
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEHHHHHHHHHHHHHHHCCHHHCCC
SSGRVPSEKGYRFYVDHLLAPQNLPNDEIVQIKDLFVERIFEAEKIAQQSAQILSELTNY
CCCCCCCCCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNI
EEEEECCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHH
LNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANML
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEECCCCCCC
SQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSI
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHC
GEEQLGTIAILGPTRMQYSRVISLLQLFTRQFTDGLKK
CHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITYSSATIRNEMADLEELGFIEKTHS
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEHHHHHHHHHHHHHHHCCHHHCCC
SSGRVPSEKGYRFYVDHLLAPQNLPNDEIVQIKDLFVERIFEAEKIAQQSAQILSELTNY
CCCCCCCCCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNI
EEEEECCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHH
LNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANML
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEECCCCCCC
SQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSI
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHC
GEEQLGTIAILGPTRMQYSRVISLLQLFTRQFTDGLKK
CHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA