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The map label for this gene is xseA

Identifier: 49187082

GI number: 49187082

Start: 4018695

End: 4020053

Strand: Reverse

Name: xseA

Synonym: BAS4084

Alternate gene names: 49187082

Gene position: 4020053-4018695 (Counterclockwise)

Preceding gene: 49187083

Following gene: 49187081

Centisome position: 76.88

GC content: 37.53

Gene sequence:

>1359_bases
ATGGAGAAACAATATTTAACCGTTACAGCGTTAACACGCTATATAAAAACAAAAATAGAATATGATCCGCATTTACAGTC
TGTTTGGTTAAAAGGTGAAATTTCCAACTTTAAAAATCATAGCCGTGGCCACATGTATTTTACATTGAAAGATGAAAATG
CAAGAATCGCAGCGGTTATGTTTGCGGGGCATAATCGTAATATTAAATTCAGACCTGAAAATGGGATGAAGGTACTCGTG
AAGGGGAAAATCTCTGTTTACGAGGCGAGTGGTTCTTATCAAATTTATATTCAAGACATGCAACCTGACGGAATTGGAAA
CCTACATTTAGCTTACGAACAATTAAAGGTTCGTTTAGAGGAAGAAGGATTGTTTTCTCAAGTTTATAAAAAAACAATCC
CTCCTTATGCGAAAACAATAGGTGTGATTACGTCACCAACAGGAGCAGCGATTCGTGATATTATAACAACGATTAAACGT
CGTTATCCAATTGGAAATGTTATTGTGTTTCCAGTACTTGTACAGGGGGAGTCAGCAGCTCCCTCAATTGTACAAGCGAT
TCGTACAGCGAATGAAATGGAAGAAATAGATGTCCTAATCGTTGGGCGTGGTGGAGGTTCTATTGAAGAATTGTGGGCGT
TTAACGAAGAAATGGTTGCAAGAGCTATTTTCAAGAGTGAAATCCCTATTATTTCAGCAGTAGGCCATGAAACAGACTTT
ACAATTGCGGATTTTGTTGCCGATTTAAGAGCGCCAACGCCAACTGCAGCGGCTGAGCTGGCAGCGCCTAATATTATAGA
GTTACAAGAAAAGGTATTACAAAGAACTTTAAGATTGCAAAGAGCAATGAGAGAGTTAGTACATAAAAAAGAAGAAAAAC
TACAAGTATTGCAAAAATCTTATGCGTTCCGTTATCCAAGACAAGTATATGAGCAAAAAGAAGAGCAATTGGATAGAGCG
TTAGAACAGCTTGTTTTAGCGAAAGAGCGCTATATTGATAAAAAGGTAAATCAGTTAAAACAGCTTTCATTTTATTTAGA
GAAGCACCACCCATCTCAAAAAATTATGCAAACGAAGGTAGCAGTTGAAACATTACAAAAGCAATTGCAACGTGAAATGC
AAACATTACTCCAAGCGAAAGAATTTGCCTTTGTAAGAGCTGCTCAAAAACTTGAAGCGCTAAGTCCGCTTAAAGTAATG
ATGAGAGGGTACGGGCTTGTATATGATGAAGAGAAGCAAGTGTTAAAAAGTGTGAAAGATGTCAGCCTTGGAGATGCTGT
TTCAGTTCAATTACAAGATGGAATACTAGATTGTAGCGTATCAGGCATAGAGGAGCGTGAATTGAATAATGGAAAATAA

Upstream 100 bases:

>100_bases
GTCCAATGACAATCACGATGCTTCTTCATAATACTGTTGAATCGGCTAAGCGTGCAGGTGTCGTTTGTAAATAATTTGAG
TCGGCTATGAGGAGAGAGAA

Downstream 100 bases:

>100_bases
ATTAAGCTTTGAAGAGGCAATTTCGCAACTTGAGCATCTCGTTTCTAAGCTAGAGCAAGGTGACGTACCTTTAGAAGAAG
CAATTTCTTATTTTAAAGAG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLV
KGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKR
RYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDF
TIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRA
LEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQAKEFAFVRAAQKLEALSPLKVM
MRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK

Sequences:

>Translated_452_residues
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLV
KGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKR
RYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDF
TIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRA
LEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQAKEFAFVRAAQKLEALSPLKVM
MRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK
>Mature_452_residues
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLV
KGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKR
RYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDF
TIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRA
LEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQAKEFAFVRAAQKLEALSPLKVM
MRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=439, Percent_Identity=42.8246013667426, Blast_Score=360, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_BACAA (C3P7V9)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868474.1
- EnsemblBacteria:   EBBACT00000126725
- GeneID:   7849190
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4421
- GeneTree:   EBGT00050000001906
- ProtClustDB:   PRK00286
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 51425; Mature: 51425

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVM
CCCCEEHHHHHHHHHHHHCCCCCCHHHEEEEEEHHHCCCCCCCEEEEEEECCCCEEEEEE
FAGHNRNIKFRPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLE
EECCCCCEEECCCCCCEEEEEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
EEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAA
HCHHHHHHHHHHCCCHHHHCCCEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCC
PSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDF
HHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCC
TIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKS
HHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AVETLQKQLQREMQTLLQAKEFAFVRAAQKLEALSPLKVMMRGYGLVYDEEKQVLKSVKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHC
VSLGDAVSVQLQDGILDCSVSGIEERELNNGK
CCCCCEEEEEEECCCEECCCCCCHHHCCCCCC
>Mature Secondary Structure
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVM
CCCCEEHHHHHHHHHHHHCCCCCCHHHEEEEEEHHHCCCCCCCEEEEEEECCCCEEEEEE
FAGHNRNIKFRPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLE
EECCCCCEEECCCCCCEEEEEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
EEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAA
HCHHHHHHHHHHCCCHHHHCCCEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCC
PSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDF
HHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCC
TIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKS
HHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AVETLQKQLQREMQTLLQAKEFAFVRAAQKLEALSPLKVMMRGYGLVYDEEKQVLKSVKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHC
VSLGDAVSVQLQDGILDCSVSGIEERELNNGK
CCCCCEEEEEEECCCEECCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA