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The map label for this gene is ptsG [H]

Identifier: 49186958

GI number: 49186958

Start: 3904413

End: 3906476

Strand: Reverse

Name: ptsG [H]

Synonym: BAS3960

Alternate gene names: 49186958

Gene position: 3906476-3904413 (Counterclockwise)

Preceding gene: 49186959

Following gene: 49186957

Centisome position: 74.71

GC content: 37.6

Gene sequence:

>2064_bases
ATGTTTAAGAAGATCTTTGGTGTTCTTCAAAAAGTCGGAAAAGCGTTAATGCTTCCAGTTGCGATTTTACCGGCAGCAGG
TATTTTACTTGGATTTGGTAATGCATTTCAAAATCCACAGTTAACAAATGTTATTCCTGCATTAAAAGCAGATTGGTTCG
TAATGGTAGCAAAAATTATGGAACAATCTGGTGATATTATTTTCGCTAACCTTGCATTATTATTCGCAGTTGGGGTAGCG
ATTGGTTTAGCTGGTGGAGATGGAGTAGCTGGTTTAGCAGCGTTCGTCGGCTACTTAATTATGAACAAAACGATGAGTGT
GTTCTTAGAAGTAGATAAGCTAGTGAAAGTAACAAGTTCTGGAGCAGATCCAGTGAAAATTGGATTTACGGATCCAGCAT
ACGCAAACGTATTAGGAATTCCAACATTACAAACAGGAGTATTTGGTGGTATTATCGTCGGTATAGTAGCGGCATATTGC
TATAATAAATACTTCAACATTGAATTACCATCATACTTAGGTTTCTTCGCAGGTAAGCGTTTCGTACCGATCGCAACTGC
AACATTCTCTTTAGTAGTAGGTATTATCATGTGCTTCGTTTGGCCATACATTCAAGGTGGCTTAAATACGTTCTCACATC
AAATGATTGATGCAAATAGAACATTAGCAGCATTCATATTCGGTTTAATTGAACGTTCATTGATTCCATTTGGATTACAT
CACATTTTCTATTCACCGTTCTGGTTCGAATTCGGTCAGTATACAAATGCAGCTGGCGAATTAATCCGTGGTGACCAAAA
AATCTTTATGGCACAGTTAAAAGACGGTGTAGAATTAACAGCAGGTACATTTACAACTGGTAAGTATCCGTTCATGATGT
TCGGTCTTCCAGCAGCAGCTTTAGCGATGTACCATGAAGCACGTCCAGAAAATAAAAAATTAGCAGCTGGTATTTTAGGT
TCTGCTGCATTAACATCTTTCTTAACAGGTATTACAGAACCACTTGAATTTTCATTCTTATTCGTAGCACCAGTACTATT
CGGAATTCATGCCGTATTCGCTGGTCTATCATTTATGACAATGCAAATTTTAGGTGTTAAAATTGGTATGACATTCTCTG
GTGGTTTAATTGACTTTATGTTATTCGGTGTATTACCAGGCCGTACAGCATGGTGGTGGGTAATTGTTGTTGGTCTTGTA
CTAGCAGTTATTTACTACTTCGGATTCCGCTTTGCAATCCGTAAATGGAATCTAAAAACACCTGGTCGTGAAGTAGCAAA
TGCGAATGACGGCGCAGGGAAAGCAGAAGCTGGTGAACTTCCTCGTGAAGTACTAGTAGCACTTGGTGGTAAAGAAAACA
TTGCTTCTTTAGACGCTTGTATTACTCGTTTACGTGTTCAAGTTAACGAACAAAAGAATGTAAACAAAGATCGTTTAAAA
GAGCTTGGAGCAGCTGGTGTACTTGAAGTTGGAAATAACATTCAAGCTATTTTTGGACCGAAATCTGACACATTAAAATC
ACAAATTCACGATATTATGTCAGGTCGTACACCTCATGTTGAAAAAGAAGAGCCTGTAAAAGTAGAAGAAGCTCTTCAAA
AAGTTGATGCAAACGAAACAATCGTTTCACCAATTGAAGGGAAAATCCTACCAATTACAGAAGTACCTGATCAAGTATTC
TCAGGAAAAATGATGGGAGACGGATTTGCAATTGAGCCGACAGAAGGAACAGTAGTTTCTCCAGTTAACGGTGAAATTGT
CAACGTATTCCCTACAAAACATGCAATTGGTATTCAATCTGAAGGCGGAAAAGAAATTTTAATCCACTTCGGTATTGATA
CTGTAAAATTAAATGGTGAAGGTTTTGAAGCACTTGTAGCACAAGGTGATAAAGTGAAACAAGGACAACCATTATTAAAA
GTAGATCTTGCATTTGTAAAAGAAAATGCACCATCTATCATTACACCAATTGTCTTTACAAATTTACAACAAGGGCAACA
AGTCGAATTGAAAAAAGATGGAAATGTTAAGAAGGGCGAAAACGCAATTATTGACATTCAGTAG

Upstream 100 bases:

>100_bases
TATACTACCCTTTGTATAGCTATCGTTCTATCTTTTTTTCCTCATGTCTTTTTGGCGTTTGTCGGAAGGTATCAATATAG
ATAAGAGAGGAAGGGCTTCC

Downstream 100 bases:

>100_bases
GAATTTGACGCAAAATGTTTATAATTATAATAGGCGATGTGGTTGACCGAACATCGCCTATTATATACAATAGATGATGT
AGTACTCACGTCTATACAAC

Product: PTS system glucose-specific transporter subunit IIABC

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MFKKIFGVLQKVGKALMLPVAILPAAGILLGFGNAFQNPQLTNVIPALKADWFVMVAKIMEQSGDIIFANLALLFAVGVA
IGLAGGDGVAGLAAFVGYLIMNKTMSVFLEVDKLVKVTSSGADPVKIGFTDPAYANVLGIPTLQTGVFGGIIVGIVAAYC
YNKYFNIELPSYLGFFAGKRFVPIATATFSLVVGIIMCFVWPYIQGGLNTFSHQMIDANRTLAAFIFGLIERSLIPFGLH
HIFYSPFWFEFGQYTNAAGELIRGDQKIFMAQLKDGVELTAGTFTTGKYPFMMFGLPAAALAMYHEARPENKKLAAGILG
SAALTSFLTGITEPLEFSFLFVAPVLFGIHAVFAGLSFMTMQILGVKIGMTFSGGLIDFMLFGVLPGRTAWWWVIVVGLV
LAVIYYFGFRFAIRKWNLKTPGREVANANDGAGKAEAGELPREVLVALGGKENIASLDACITRLRVQVNEQKNVNKDRLK
ELGAAGVLEVGNNIQAIFGPKSDTLKSQIHDIMSGRTPHVEKEEPVKVEEALQKVDANETIVSPIEGKILPITEVPDQVF
SGKMMGDGFAIEPTEGTVVSPVNGEIVNVFPTKHAIGIQSEGGKEILIHFGIDTVKLNGEGFEALVAQGDKVKQGQPLLK
VDLAFVKENAPSIITPIVFTNLQQGQQVELKKDGNVKKGENAIIDIQ

Sequences:

>Translated_687_residues
MFKKIFGVLQKVGKALMLPVAILPAAGILLGFGNAFQNPQLTNVIPALKADWFVMVAKIMEQSGDIIFANLALLFAVGVA
IGLAGGDGVAGLAAFVGYLIMNKTMSVFLEVDKLVKVTSSGADPVKIGFTDPAYANVLGIPTLQTGVFGGIIVGIVAAYC
YNKYFNIELPSYLGFFAGKRFVPIATATFSLVVGIIMCFVWPYIQGGLNTFSHQMIDANRTLAAFIFGLIERSLIPFGLH
HIFYSPFWFEFGQYTNAAGELIRGDQKIFMAQLKDGVELTAGTFTTGKYPFMMFGLPAAALAMYHEARPENKKLAAGILG
SAALTSFLTGITEPLEFSFLFVAPVLFGIHAVFAGLSFMTMQILGVKIGMTFSGGLIDFMLFGVLPGRTAWWWVIVVGLV
LAVIYYFGFRFAIRKWNLKTPGREVANANDGAGKAEAGELPREVLVALGGKENIASLDACITRLRVQVNEQKNVNKDRLK
ELGAAGVLEVGNNIQAIFGPKSDTLKSQIHDIMSGRTPHVEKEEPVKVEEALQKVDANETIVSPIEGKILPITEVPDQVF
SGKMMGDGFAIEPTEGTVVSPVNGEIVNVFPTKHAIGIQSEGGKEILIHFGIDTVKLNGEGFEALVAQGDKVKQGQPLLK
VDLAFVKENAPSIITPIVFTNLQQGQQVELKKDGNVKKGENAIIDIQ
>Mature_687_residues
MFKKIFGVLQKVGKALMLPVAILPAAGILLGFGNAFQNPQLTNVIPALKADWFVMVAKIMEQSGDIIFANLALLFAVGVA
IGLAGGDGVAGLAAFVGYLIMNKTMSVFLEVDKLVKVTSSGADPVKIGFTDPAYANVLGIPTLQTGVFGGIIVGIVAAYC
YNKYFNIELPSYLGFFAGKRFVPIATATFSLVVGIIMCFVWPYIQGGLNTFSHQMIDANRTLAAFIFGLIERSLIPFGLH
HIFYSPFWFEFGQYTNAAGELIRGDQKIFMAQLKDGVELTAGTFTTGKYPFMMFGLPAAALAMYHEARPENKKLAAGILG
SAALTSFLTGITEPLEFSFLFVAPVLFGIHAVFAGLSFMTMQILGVKIGMTFSGGLIDFMLFGVLPGRTAWWWVIVVGLV
LAVIYYFGFRFAIRKWNLKTPGREVANANDGAGKAEAGELPREVLVALGGKENIASLDACITRLRVQVNEQKNVNKDRLK
ELGAAGVLEVGNNIQAIFGPKSDTLKSQIHDIMSGRTPHVEKEEPVKVEEALQKVDANETIVSPIEGKILPITEVPDQVF
SGKMMGDGFAIEPTEGTVVSPVNGEIVNVFPTKHAIGIQSEGGKEILIHFGIDTVKLNGEGFEALVAQGDKVKQGQPLLK
VDLAFVKENAPSIITPIVFTNLQQGQQVELKKDGNVKKGENAIIDIQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=708, Percent_Identity=37.9943502824859, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1787343, Length=513, Percent_Identity=47.1734892787524, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1787908, Length=518, Percent_Identity=39.1891891891892, Blast_Score=333, Evalue=3e-92,
Organism=Escherichia coli, GI1788757, Length=147, Percent_Identity=42.8571428571429, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1790159, Length=140, Percent_Identity=42.8571428571429, Blast_Score=115, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 74084; Mature: 74084

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKIFGVLQKVGKALMLPVAILPAAGILLGFGNAFQNPQLTNVIPALKADWFVMVAKIM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EQSGDIIFANLALLFAVGVAIGLAGGDGVAGLAAFVGYLIMNKTMSVFLEVDKLVKVTSS
HCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GADPVKIGFTDPAYANVLGIPTLQTGVFGGIIVGIVAAYCYNKYFNIELPSYLGFFAGKR
CCCCEEECCCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCC
FVPIATATFSLVVGIIMCFVWPYIQGGLNTFSHQMIDANRTLAAFIFGLIERSLIPFGLH
EEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
HIFYSPFWFEFGQYTNAAGELIRGDQKIFMAQLKDGVELTAGTFTTGKYPFMMFGLPAAA
HHHHCHHHHHHHHHCCHHHHHHCCCHHHHHHHHCCCCEEEECEEECCCCCCEEECCHHHH
LAMYHEARPENKKLAAGILGSAALTSFLTGITEPLEFSFLFVAPVLFGIHAVFAGLSFMT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQILGVKIGMTFSGGLIDFMLFGVLPGRTAWWWVIVVGLVLAVIYYFGFRFAIRKWNLKT
HHHHHEEEECEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
PGREVANANDGAGKAEAGELPREVLVALGGKENIASLDACITRLRVQVNEQKNVNKDRLK
CCHHHCCCCCCCCCCCHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
ELGAAGVLEVGNNIQAIFGPKSDTLKSQIHDIMSGRTPHVEKEEPVKVEEALQKVDANET
HCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCC
IVSPIEGKILPITEVPDQVFSGKMMGDGFAIEPTEGTVVSPVNGEIVNVFPTKHAIGIQS
EECCCCCCEEEECCCCHHHHCCCCCCCCEEECCCCCCEECCCCCCEEEEECCCEEECCCC
EGGKEILIHFGIDTVKLNGEGFEALVAQGDKVKQGQPLLKVDLAFVKENAPSIITPIVFT
CCCCEEEEEECCEEEEECCCCHHHHHHCCCCCCCCCCCCEEHHHHHHCCCCCHHHHHHHH
NLQQGQQVELKKDGNVKKGENAIIDIQ
CCCCCCEEEEECCCCCCCCCCCEEEEC
>Mature Secondary Structure
MFKKIFGVLQKVGKALMLPVAILPAAGILLGFGNAFQNPQLTNVIPALKADWFVMVAKIM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EQSGDIIFANLALLFAVGVAIGLAGGDGVAGLAAFVGYLIMNKTMSVFLEVDKLVKVTSS
HCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GADPVKIGFTDPAYANVLGIPTLQTGVFGGIIVGIVAAYCYNKYFNIELPSYLGFFAGKR
CCCCEEECCCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCC
FVPIATATFSLVVGIIMCFVWPYIQGGLNTFSHQMIDANRTLAAFIFGLIERSLIPFGLH
EEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
HIFYSPFWFEFGQYTNAAGELIRGDQKIFMAQLKDGVELTAGTFTTGKYPFMMFGLPAAA
HHHHCHHHHHHHHHCCHHHHHHCCCHHHHHHHHCCCCEEEECEEECCCCCCEEECCHHHH
LAMYHEARPENKKLAAGILGSAALTSFLTGITEPLEFSFLFVAPVLFGIHAVFAGLSFMT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQILGVKIGMTFSGGLIDFMLFGVLPGRTAWWWVIVVGLVLAVIYYFGFRFAIRKWNLKT
HHHHHEEEECEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
PGREVANANDGAGKAEAGELPREVLVALGGKENIASLDACITRLRVQVNEQKNVNKDRLK
CCHHHCCCCCCCCCCCHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
ELGAAGVLEVGNNIQAIFGPKSDTLKSQIHDIMSGRTPHVEKEEPVKVEEALQKVDANET
HCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCC
IVSPIEGKILPITEVPDQVFSGKMMGDGFAIEPTEGTVVSPVNGEIVNVFPTKHAIGIQS
EECCCCCCEEEECCCCHHHHCCCCCCCCEEECCCCCCEECCCCCCEEEEECCCEEECCCC
EGGKEILIHFGIDTVKLNGEGFEALVAQGDKVKQGQPLLKVDLAFVKENAPSIITPIVFT
CCCCEEEEEECCEEEEECCCCHHHHHHCCCCCCCCCCCCEEHHHHHHCCCCCHHHHHHHH
NLQQGQQVELKKDGNVKKGENAIIDIQ
CCCCCCEEEEECCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]