Click here to switch to the map view.

The map label for this gene is yrhP [H]

Identifier: 49184764

GI number: 49184764

Start: 1774699

End: 1775325

Strand: Direct

Name: yrhP [H]

Synonym: BAS1752

Alternate gene names: 49184764

Gene position: 1774699-1775325 (Clockwise)

Preceding gene: 49184763

Following gene: 49184765

Centisome position: 33.94

GC content: 32.38

Gene sequence:

>627_bases
ATGGAAAATTATTTATTGTTTATCCTTACAGCAATGCTAATTATAATAATGCCTGGTCCTGGTTTCGCACTAGTTACAAA
AAATACTATCTCGTATGGCACAAATGGTGGAATAAAGACTGTCTTAGGAACGATATCTGGAATGATGATTCATACAATAA
TGGCTACGCTAGGACTCTCGGCCATTCTAATGAAATTTTCTATGTTATTTATATTTATTAAATATGCTGGGGCTTTGTAT
TTAATTTACTTAGCTATCAAGTCAATTAAAAGTGCCTTTTCTAAAAAAGAAGATATGCAAGTTTCGGTGGAAATGAACGC
TAAGGATATTGGGACGATTAAAAGTTTTAGACAAGGATTTACAACGGCAATCTTAAACCCAAAAACGGCTGTATTTTTCT
TAAGCTTTCTCCCACAATTTATTGTGAATAATCAAAGTCATTTCTTCCAATTTCTTTTGTTAGGACTCACATTTACGACT
TTGACCGCAATATGGTATTTGCTTTATATCTCGCTAATACGTCAATTAAGAACTTTTTTAAGAAAAGAAAGAGTGAACCG
TACAATAGAGGGTATTACGGGCGCAGTATTATTAGTATTTGGGGTTAGATTATTTTTCCAAAAATAA

Upstream 100 bases:

>100_bases
ACATAAATAAACTTCTGATCAAGCTTTTTATATGTAATGTTTTAATGAAAAAAGCTATACTGTAAGCAAAACTAAAAAAT
TGGAAAGGAAATACTAGAAC

Downstream 100 bases:

>100_bases
ATATGTATATGAAAAAGAGAAATAATCAATAGTGGTTATTTCTCTTATTTATTCTAATACTATTTCACACTTACATACTA
ATTTGAGTTTTAAAAATGAG

Product: homoserine/threonine efflux protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MENYLLFILTAMLIIIMPGPGFALVTKNTISYGTNGGIKTVLGTISGMMIHTIMATLGLSAILMKFSMLFIFIKYAGALY
LIYLAIKSIKSAFSKKEDMQVSVEMNAKDIGTIKSFRQGFTTAILNPKTAVFFLSFLPQFIVNNQSHFFQFLLLGLTFTT
LTAIWYLLYISLIRQLRTFLRKERVNRTIEGITGAVLLVFGVRLFFQK

Sequences:

>Translated_208_residues
MENYLLFILTAMLIIIMPGPGFALVTKNTISYGTNGGIKTVLGTISGMMIHTIMATLGLSAILMKFSMLFIFIKYAGALY
LIYLAIKSIKSAFSKKEDMQVSVEMNAKDIGTIKSFRQGFTTAILNPKTAVFFLSFLPQFIVNNQSHFFQFLLLGLTFTT
LTAIWYLLYISLIRQLRTFLRKERVNRTIEGITGAVLLVFGVRLFFQK
>Mature_208_residues
MENYLLFILTAMLIIIMPGPGFALVTKNTISYGTNGGIKTVLGTISGMMIHTIMATLGLSAILMKFSMLFIFIKYAGALY
LIYLAIKSIKSAFSKKEDMQVSVEMNAKDIGTIKSFRQGFTTAILNPKTAVFFLSFLPQFIVNNQSHFFQFLLLGLTFTT
LTAIWYLLYISLIRQLRTFLRKERVNRTIEGITGAVLLVFGVRLFFQK

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=208, Percent_Identity=24.5192307692308, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI48994978, Length=209, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788099, Length=205, Percent_Identity=28.2926829268293, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23445; Mature: 23445

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENYLLFILTAMLIIIMPGPGFALVTKNTISYGTNGGIKTVLGTISGMMIHTIMATLGLS
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AILMKFSMLFIFIKYAGALYLIYLAIKSIKSAFSKKEDMQVSVEMNAKDIGTIKSFRQGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHH
TTAILNPKTAVFFLSFLPQFIVNNQSHFFQFLLLGLTFTTLTAIWYLLYISLIRQLRTFL
HHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKERVNRTIEGITGAVLLVFGVRLFFQK
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENYLLFILTAMLIIIMPGPGFALVTKNTISYGTNGGIKTVLGTISGMMIHTIMATLGLS
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AILMKFSMLFIFIKYAGALYLIYLAIKSIKSAFSKKEDMQVSVEMNAKDIGTIKSFRQGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHH
TTAILNPKTAVFFLSFLPQFIVNNQSHFFQFLLLGLTFTTLTAIWYLLYISLIRQLRTFL
HHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKERVNRTIEGITGAVLLVFGVRLFFQK
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]