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The map label for this gene is hblA [H]

Identifier: 49184763

GI number: 49184763

Start: 1773386

End: 1774303

Strand: Direct

Name: hblA [H]

Synonym: BAS1751

Alternate gene names: 49184763

Gene position: 1773386-1774303 (Clockwise)

Preceding gene: 49184762

Following gene: 49184764

Centisome position: 33.92

GC content: 34.1

Gene sequence:

>918_bases
ATGCAGAAACGATTTTATAAAAAATGTCTTTTAACGTTAATGATTGCTGGGGTGGCAACGAGTAACGCATTACCTTTACA
TCCTTTTGCAGCAGAACAAAACGTAAAAGTACTACAAGAAAATGCGAAAGATTATTCTCTTGGTCCAGCAGGATTCCAAG
ATGTAATGGCACAAACAACATCGAGCATATTCGCAATGGATTCATATGCAAAGTTAATCCAAAATCAGCAAGAAACGGAT
TTAAGCAAAATAAGTTCGATTAATAGTGAGTTTAAAGGAAATATGATGCAGCACCAACGAGATGCAAAAATTAACGCGAC
GTATTGGTTAGATCGTATGAAGCCGCAAATTATGAAAACGGATCAAAATATTATTAATTACAATAATACTTTTCAAACAT
ATTATAATAGCATGTTAATTGCGATTGATCAAAAAGATAGCGTAAAGTTGAAAGCGAATTTAGAAAAATTGTATGCGGAT
ATTGTAAAGAATCAAAATGAGGTAGATGTATTATTAGGAGATTTGAAAGCCTTTCGTGATAGAATGGCGAAAGATACAAA
TAGCTTTAAAGAGGATACAAATCAACTAACCTCGATTTTGGCAAGTACGAATGCTGGAATCCCCGCTCTAGAGCAACAAA
TCAATACATATAATGATTCAATTAAAAAGAGTAATGATATGGTCATTGCTGGTGGTGTACTTTGCGTAGCGTTAATAACA
TGTCTTGCTGGGGGATCTATGATTGCCGTTGCGAAAAAAGATATTGCAAATGCAGAACGAGAAATCGCTAATTTAAAAGA
TAGAATTTCTGGAGCGCAAGCAGAAGTCGCAATTTTGACAGATGTAAAAAATAAAACAACAAATATGACGGAAACGATTG
ATGCAGCAATTACAGCACTGCAAAACATATCAAATTAA

Upstream 100 bases:

>100_bases
CGAATCGTTAGAGCGTTAAGTGTTGATGAATGATTTGAAGCTCCTGTTCAGTTGTGAGCAGGAGCTTTTTATACCCTTAT
AAAGAAACTAGGTGAAAAGT

Downstream 100 bases:

>100_bases
TGGTATACAGTAGGGGCAAAGTATAATAATTTACTACAAAACGTAAAAGGAATTAGCCCAGAAGAATTTACGTTTATAAA
AGAAGATTTACATACAGCAA

Product: enterotoxin B

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MQKRFYKKCLLTLMIAGVATSNALPLHPFAAEQNVKVLQENAKDYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQETD
LSKISSINSEFKGNMMQHQRDAKINATYWLDRMKPQIMKTDQNIINYNNTFQTYYNSMLIAIDQKDSVKLKANLEKLYAD
IVKNQNEVDVLLGDLKAFRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
CLAGGSMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISN

Sequences:

>Translated_305_residues
MQKRFYKKCLLTLMIAGVATSNALPLHPFAAEQNVKVLQENAKDYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQETD
LSKISSINSEFKGNMMQHQRDAKINATYWLDRMKPQIMKTDQNIINYNNTFQTYYNSMLIAIDQKDSVKLKANLEKLYAD
IVKNQNEVDVLLGDLKAFRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
CLAGGSMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISN
>Mature_305_residues
MQKRFYKKCLLTLMIAGVATSNALPLHPFAAEQNVKVLQENAKDYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQETD
LSKISSINSEFKGNMMQHQRDAKINATYWLDRMKPQIMKTDQNIINYNNTFQTYYNSMLIAIDQKDSVKLKANLEKLYAD
IVKNQNEVDVLLGDLKAFRDRMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
CLAGGSMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISN

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 33755; Mature: 33755

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRFYKKCLLTLMIAGVATSNALPLHPFAAEQNVKVLQENAKDYSLGPAGFQDVMAQTT
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHH
SSIFAMDSYAKLIQNQQETDLSKISSINSEFKGNMMQHQRDAKINATYWLDRMKPQIMKT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHCHHHHHC
DQNIINYNNTFQTYYNSMLIAIDQKDSVKLKANLEKLYADIVKNQNEVDVLLGDLKAFRD
CCHHHCCCCHHHHHHCCEEEEECCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHH
CLAGGSMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITAL
HHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
QNISN
HHCCC
>Mature Secondary Structure
MQKRFYKKCLLTLMIAGVATSNALPLHPFAAEQNVKVLQENAKDYSLGPAGFQDVMAQTT
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHH
SSIFAMDSYAKLIQNQQETDLSKISSINSEFKGNMMQHQRDAKINATYWLDRMKPQIMKT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHCHHHHHC
DQNIINYNNTFQTYYNSMLIAIDQKDSVKLKANLEKLYADIVKNQNEVDVLLGDLKAFRD
CCHHHCCCCHHHHHHCCEEEEECCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RMAKDTNSFKEDTNQLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHH
CLAGGSMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITAL
HHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
QNISN
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]