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The map label for this gene is trpB

Identifier: 49184180

GI number: 49184180

Start: 1207515

End: 1208708

Strand: Direct

Name: trpB

Synonym: BAS1161

Alternate gene names: 49184180

Gene position: 1207515-1208708 (Clockwise)

Preceding gene: 49184179

Following gene: 49184181

Centisome position: 23.09

GC content: 42.04

Gene sequence:

>1194_bases
ATGAACTACGCATATCCAGATGAAAAAGGTCACTACGGTATATACGGAGGACGATACGTTCCAGAAACGTTAATGCAATC
TGTATTAGAACTAGAAGAAGCATATAAAGAGGCGATGGAAGATGAAGCATTTCAAAAGGAATTAAATCATTATTTAAAAA
CGTATGTCGGAAGAGAAACACCGCTTTATTTCGCTGAGAATATGACGGAGTATTGCGGAGGTGCAAAGATTTATTTAAAA
CGTGAAGATTTGAACCATACAGGAGCTCATAAAATTAACAATACAATTGGTCAGGCACTTCTTGCGGTGCGAATGGGCAA
GAAAAAAGTTGTCGCTGAAACAGGGGCTGGACAACACGGTGTTGCAACAGCTACGGTATGTGCCCTTCTCGGTTTAGAGT
GCGTCATCTTTATGGGAGAAGAAGATGTGAGACGTCAAAAATTAAATGTGTTTCGAATGGAATTACTCGGAGCGAAAGTA
GAAAGTGTAGCGGCAGGTAGCGGTACATTAAAAGATGCGGTAAACGAGGCGCTTCGTTACTGGGTTTCACACGTGCATGA
TACGCACTACATTATGGGATCTGTTCTCGGACCGCATCCATTCCCGCAAATTGTCCGTGATTTCCAAAGTGTAATTGGGA
ATGAGACGAAAAAACAATATGAAGCGTTAGAAGGAAAGTTACCAGAAGCAGTCGTTGCTTGCATTGGTGGTGGGAGTAAC
GCAATGGGAATGTTTTATCCGTTTGTACATGATGAAGAAGTTGCTCTTTACGGCGTAGAAGCAGCTGGAAAAGGTGTTCA
TACAGAAAAGCATGCAGCAACTTTAACGAAAGGAAGCGTCGGCGTTTTACACGGATCGATGATGTATCTTCTGCAAAATG
AAGAAGGACAAATTCAAGAAGCGCACTCTATTTCAGCAGGACTTGATTACCCAGGTGTTGGTCCAGAACATAGCTTGCTA
AAAGATATTGGCCGCGTTTCTTATCATTCCATTACTGATGATGAGGCGTTAGAAGCGTTTCAGTTATTAACGAAAAAAGA
AGGGATTATCCCGGCGTTAGAAAGCTCGCATGCTGTCGCATACGCATTAAAATTAGCGCCGCAAATGAAGGAAGATGAAG
GACTTGTCATTTGTTTATCCGGCCGTGGTGATAAAGATGTAGAGAGTATAAAACGTTACATGGAAGAGGTGTAA

Upstream 100 bases:

>100_bases
GGCCATATATGGTTGATGTGAGCAGCGGAGTAGAGACAGAAGGAAAGAAAGATGTAGAGAAAATAAAACAATTTATTATA
AAAGCGAAGGAGTGTTCTAA

Downstream 100 bases:

>100_bases
AAAATGGGAGTAGAAAGAATTAAAGCAGCATTTGAAAATGGTAAGAAAGCATTTATTCCGTACGTAATGGGCGGAGATGG
TGGCCTTGAAATATTAAAAG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV

Sequences:

>Translated_397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV
>Mature_397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=55.1181102362205, Blast_Score=422, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6321412, Length=388, Percent_Identity=57.9896907216495, Blast_Score=473, Evalue=1e-134,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_BACAA (C3P3U0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002865769.1
- ProteinModelPortal:   C3P3U0
- SMR:   C3P3U0
- EnsemblBacteria:   EBBACT00000128173
- GeneID:   7849830
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1329
- GeneTree:   EBGT00050000001631
- ProtClustDB:   PRK04346
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 43590; Mature: 43590

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRET
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHG
CHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCC
VATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRY
HHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
HHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCC
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQE
CCCEEECCCCCCCEEEEEEHHCCCCCCCHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHH
AHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
YALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV
HHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRET
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHG
CHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCC
VATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRY
HHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
HHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCC
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQE
CCCEEECCCCCCCEEEEEEHHCCCCCCCHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHH
AHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
YALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV
HHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA