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The map label for this gene is trpF

Identifier: 49184179

GI number: 49184179

Start: 1206904

End: 1207518

Strand: Direct

Name: trpF

Synonym: BAS1160

Alternate gene names: 49184179

Gene position: 1206904-1207518 (Clockwise)

Preceding gene: 49184178

Following gene: 49184180

Centisome position: 23.08

GC content: 37.89

Gene sequence:

>615_bases
ATGAAAGTGAAAATTTGCGGTATCACTGATATGGAAACAGCAAAACGTGCTTGCGAATACGGAGCTGATGCACTTGGATT
TGTTTTTGCAGAAAGTAAGCGGAAAATTACTCCAGGGCTAGCGAAAGAAATCATTCAGGAACTTCCAGCCAACGTGTTAA
AAATCGGTGTTTTCGTAAATGAATCAGTAGAAGTAATCCAGAAAATTACAGGGAATTGCGGATTAACACATGTACAACTA
CATGGGGGTGAAGACAATCATCAAATCAGAAGATTGAATATTCCGTCTATAAAGTCGCTCGGAGTAACTTCAGAGAGTGA
TATGAAAAACGCTCAAGGGTATGAAACGGACTATATATTATTTGATAGCCCGAAGGAAAAGTTTCATGGAGGAAATGGAA
AGACATTTCCTTGGGAGTTACTTGCGCATATGCCAAAAGAATTACGAGAGAAAACGATATTAGCTGGTGGATTAAACACT
CTTAATATAGAAGAAGCAATTCGAACTGTTCGGCCATATATGGTTGATGTGAGCAGCGGAGTAGAGACAGAAGGAAAGAA
AGATGTAGAGAAAATAAAACAATTTATTATAAAAGCGAAGGAGTGTTCTAAATGA

Upstream 100 bases:

>100_bases
TCCGCGTTAAACGAGCTGGGGCAAAAGGTGTATTAGTTGGAGAAGCGCTTATGACATCGTCTTCTATTCATACCTTTTTT
GAAGATTGTAAGGTGAACAT

Downstream 100 bases:

>100_bases
ACTACGCATATCCAGATGAAAAAGGTCACTACGGTATATACGGAGGACGATACGTTCCAGAAACGTTAATGCAATCTGTA
TTAGAACTAGAAGAAGCATA

Product: N-(5'-phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVNESVEVIQKITGNCGLTHVQL
HGGEDNHQIRRLNIPSIKSLGVTSESDMKNAQGYETDYILFDSPKEKFHGGNGKTFPWELLAHMPKELREKTILAGGLNT
LNIEEAIRTVRPYMVDVSSGVETEGKKDVEKIKQFIIKAKECSK

Sequences:

>Translated_204_residues
MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVNESVEVIQKITGNCGLTHVQL
HGGEDNHQIRRLNIPSIKSLGVTSESDMKNAQGYETDYILFDSPKEKFHGGNGKTFPWELLAHMPKELREKTILAGGLNT
LNIEEAIRTVRPYMVDVSSGVETEGKKDVEKIKQFIIKAKECSK
>Mature_204_residues
MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVNESVEVIQKITGNCGLTHVQL
HGGEDNHQIRRLNIPSIKSLGVTSESDMKNAQGYETDYILFDSPKEKFHGGNGKTFPWELLAHMPKELREKTILAGGLNT
LNIEEAIRTVRPYMVDVSSGVETEGKKDVEKIKQFIIKAKECSK

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family

Homologues:

Organism=Saccharomyces cerevisiae, GI6320210, Length=217, Percent_Identity=32.258064516129, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPF_BACAA (C3P3T9)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002865768.1
- ProteinModelPortal:   C3P3T9
- SMR:   C3P3T9
- EnsemblBacteria:   EBBACT00000127671
- GeneID:   7848125
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1328
- GeneTree:   EBGT00050000002322
- ProtClustDB:   PRK01222
- HAMAP:   MF_00135_B
- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF00697 PRAI; SSF51366 RibP_bind_barrel

EC number: =5.3.1.24

Molecular weight: Translated: 22619; Mature: 22619

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVN
CEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCCHHHEEHHHHCC
ESVEVIQKITGNCGLTHVQLHGGEDNHQIRRLNIPSIKSLGVTSESDMKNAQGYETDYIL
HHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCHHCCCCCCHHHCCCCCCCCCEEE
FDSPKEKFHGGNGKTFPWELLAHMPKELREKTILAGGLNTLNIEEAIRTVRPYMVDVSSG
ECCCHHHHCCCCCCCCHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEECCCC
VETEGKKDVEKIKQFIIKAKECSK
CCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVKICGITDMETAKRACEYGADALGFVFAESKRKITPGLAKEIIQELPANVLKIGVFVN
CEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCCHHHEEHHHHCC
ESVEVIQKITGNCGLTHVQLHGGEDNHQIRRLNIPSIKSLGVTSESDMKNAQGYETDYIL
HHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCHHCCCCCCHHHCCCCCCCCCEEE
FDSPKEKFHGGNGKTFPWELLAHMPKELREKTILAGGLNTLNIEEAIRTVRPYMVDVSSG
ECCCHHHHCCCCCCCCHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEECCCC
VETEGKKDVEKIKQFIIKAKECSK
CCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA