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The map label for this gene is trpD

Identifier: 49184177

GI number: 49184177

Start: 1205119

End: 1206144

Strand: Direct

Name: trpD

Synonym: BAS1158

Alternate gene names: 49184177

Gene position: 1205119-1206144 (Clockwise)

Preceding gene: 49184176

Following gene: 49184178

Centisome position: 23.05

GC content: 37.62

Gene sequence:

>1026_bases
ATGAATAACTATCTTCGTAAATTAGTGGAGGGACAACATTTAACAGAAGAGGAAATGTATAAAGCGGGGCTTCTTTTATT
AAATGAAAACATATTGGAAAGTGAAATTGCAGCTTTCTTAGTTTTACTGAAAGCGAAAGGTGAAACTGCAGAAGAAATAT
ACGGTCTCGTTCGAGCTCTTCGCGAAAAGGCATTACCGTTTTCGAATCATATACAAGGCGCGATGGACAATTGCGGGACA
GGTGGTGACGGTGCCCAAACGTTTAATATTAGCACAACATCCGCATTTGTACTGGCAGGAGCTGGCGTAAAGGTTGCAAA
ACATGGTAATCGTGCTGTTTCTAGTAAAACAGGAAGTGCAGATTTATTAGAAGAACTCGGTGTAAACATTAGTAGTACGC
CAAACGAAATTGATTATTTATTAGAGCATGTCGGAATCGCATTTTTATTCGCACCAGCGATGCATCCAGCATTAAAGCGC
ATTATGAAAATAAGAAAAGAATTAAACGTTCCGACGATCTTTAACTTAATTGGACCGTTAACAAATCCGGTGAATTTAGA
AACACAATTTGTCGGCATTTATAAACGAGATATGTTACTACCAGTTGCGCAAGTACTACAGAAACTAGGAAGAAAACAAG
CACTTGTCGTAAACGGAAGTGGGTTTTTAGATGAAGCATCATTGCAAGGAGAAAATCATGTTGTCATTTTAAAAGATAAT
GAAATAGTAGAAACGAGTATTGAACCTGAGAAATATGGATTCTCAATAGTGAAAAACGAAGAGATTAGAGGCGGGAATTC
GAAAGAAAATGCAAAGATTACGCTCGGAGTATTAAGCGGAGAAAAAAGTGTTTACCGTGATACTGTTTTATTCAATGCAG
GACTTGCCCTTTTCGCAAATGGAAAAGCAAAGACGATTGAAGAAGGAATAACACTCGCAGCACATAGCATTGACTCTGGA
AAAGCATTAGCGAAACTAAACTTATTAATTGCAGCAAGTAACGAAGAATTAGAAAGGGTGAATTAA

Upstream 100 bases:

>100_bases
CGCTCTTCGGATTACAGTTTCATCCGGAATCAATCGCGACAGAAGAAGGGGGAAAGTTAATACGTGCCTTTTTAGGCGAA
GTGAAAGAGGAGGAAAGAGT

Downstream 100 bases:

>100_bases
AGTGGGGACGATTTTAGACAAAATTGTAAATCAAAAGAAAAAGGAAGTTGCGGCATTATATGAAACATATACACCAGTAA
AAGAAAAAAGAAAAACGCGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNNYLRKLVEGQHLTEEEMYKAGLLLLNENILESEIAAFLVLLKAKGETAEEIYGLVRALREKALPFSNHIQGAMDNCGT
GGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSADLLEELGVNISSTPNEIDYLLEHVGIAFLFAPAMHPALKR
IMKIRKELNVPTIFNLIGPLTNPVNLETQFVGIYKRDMLLPVAQVLQKLGRKQALVVNGSGFLDEASLQGENHVVILKDN
EIVETSIEPEKYGFSIVKNEEIRGGNSKENAKITLGVLSGEKSVYRDTVLFNAGLALFANGKAKTIEEGITLAAHSIDSG
KALAKLNLLIAASNEELERVN

Sequences:

>Translated_341_residues
MNNYLRKLVEGQHLTEEEMYKAGLLLLNENILESEIAAFLVLLKAKGETAEEIYGLVRALREKALPFSNHIQGAMDNCGT
GGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSADLLEELGVNISSTPNEIDYLLEHVGIAFLFAPAMHPALKR
IMKIRKELNVPTIFNLIGPLTNPVNLETQFVGIYKRDMLLPVAQVLQKLGRKQALVVNGSGFLDEASLQGENHVVILKDN
EIVETSIEPEKYGFSIVKNEEIRGGNSKENAKITLGVLSGEKSVYRDTVLFNAGLALFANGKAKTIEEGITLAAHSIDSG
KALAKLNLLIAASNEELERVN
>Mature_341_residues
MNNYLRKLVEGQHLTEEEMYKAGLLLLNENILESEIAAFLVLLKAKGETAEEIYGLVRALREKALPFSNHIQGAMDNCGT
GGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSADLLEELGVNISSTPNEIDYLLEHVGIAFLFAPAMHPALKR
IMKIRKELNVPTIFNLIGPLTNPVNLETQFVGIYKRDMLLPVAQVLQKLGRKQALVVNGSGFLDEASLQGENHVVILKDN
EIVETSIEPEKYGFSIVKNEEIRGGNSKENAKITLGVLSGEKSVYRDTVLFNAGLALFANGKAKTIEEGITLAAHSIDSG
KALAKLNLLIAASNEELERVN

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=277, Percent_Identity=39.3501805054152, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320561, Length=275, Percent_Identity=32.7272727272727, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_BACAA (C3P3T7)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002865766.1
- ProteinModelPortal:   C3P3T7
- SMR:   C3P3T7
- EnsemblBacteria:   EBBACT00000126283
- GeneID:   7848540
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1326
- GeneTree:   EBGT00050000002544
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36894; Mature: 36894

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNYLRKLVEGQHLTEEEMYKAGLLLLNENILESEIAAFLVLLKAKGETAEEIYGLVRAL
CCHHHHHHHCCCCCCHHHHHHHCHHEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
REKALPFSNHIQGAMDNCGTGGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSA
HHHCCCCHHHHCHHHHCCCCCCCCCEEEEEECCCEEEEECCCEEEEECCCCHHCCCCCCH
DLLEELGVNISSTPNEIDYLLEHVGIAFLFAPAMHPALKRIMKIRKELNVPTIFNLIGPL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
TNPVNLETQFVGIYKRDMLLPVAQVLQKLGRKQALVVNGSGFLDEASLQGENHVVILKDN
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEECC
EIVETSIEPEKYGFSIVKNEEIRGGNSKENAKITLGVLSGEKSVYRDTVLFNAGLALFAN
CEEECCCCHHHCCEEEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHEECCEEEEEC
GKAKTIEEGITLAAHSIDSGKALAKLNLLIAASNEELERVN
CCCHHHHHCCEEEEECCCCCCCEEEEEEEEEECCCHHHCCC
>Mature Secondary Structure
MNNYLRKLVEGQHLTEEEMYKAGLLLLNENILESEIAAFLVLLKAKGETAEEIYGLVRAL
CCHHHHHHHCCCCCCHHHHHHHCHHEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
REKALPFSNHIQGAMDNCGTGGDGAQTFNISTTSAFVLAGAGVKVAKHGNRAVSSKTGSA
HHHCCCCHHHHCHHHHCCCCCCCCCEEEEEECCCEEEEECCCEEEEECCCCHHCCCCCCH
DLLEELGVNISSTPNEIDYLLEHVGIAFLFAPAMHPALKRIMKIRKELNVPTIFNLIGPL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
TNPVNLETQFVGIYKRDMLLPVAQVLQKLGRKQALVVNGSGFLDEASLQGENHVVILKDN
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEEECC
EIVETSIEPEKYGFSIVKNEEIRGGNSKENAKITLGVLSGEKSVYRDTVLFNAGLALFAN
CEEECCCCHHHCCEEEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHEECCEEEEEC
GKAKTIEEGITLAAHSIDSGKALAKLNLLIAASNEELERVN
CCCHHHHHCCEEEEECCCCCCCEEEEEEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA