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The map label for this gene is trpGD [H]

Identifier: 49184176

GI number: 49184176

Start: 1204535

End: 1205122

Strand: Direct

Name: trpGD [H]

Synonym: BAS1157

Alternate gene names: 49184176

Gene position: 1204535-1205122 (Clockwise)

Preceding gene: 49184175

Following gene: 49184177

Centisome position: 23.04

GC content: 40.31

Gene sequence:

>588_bases
ATGATTGTACTGATCGATAATTATGATTCATTCACATATAACTTGTATCAACTATTAGGCGAATACGAAGAAGAAATTGT
TGTCGTAAGAAATGATCAAATAACGATAGAACAATTAGAAGAAATGAACCCAAAAGGAATTGTGCTTTCGCCAGGACCAG
GAAAACCAGAGGAGGCTGGTATTTGTATTGAAGTAATTCGTCATTTTTATAAGAACGTTCCCATATTAGGTATTTGCCTT
GGTCATCAAGCAATTATATCAGCATTTGGAGGAGAGATTGTAAGAGCAGAGCGCATTAAACACGGAAAAACATCGCGTGC
GAAACATAACGGAACGTCAATCTTTTCGTATGTGACGCAGCCGCTAACAGCGATGCGCTACCATTCTCTTGTTGCCGCAC
AAACGAGCTTGCCACAATGTTTTGACATATTAGCGACAGCGATGGACGATGGAGAAATAATGGCAGTTCGTCACAATTAT
TATCCGCTCTTCGGATTACAGTTTCATCCGGAATCAATCGCGACAGAAGAAGGGGGAAAGTTAATACGTGCCTTTTTAGG
CGAAGTGAAAGAGGAGGAAAGAGTATGA

Upstream 100 bases:

>100_bases
CATACGTTCAGGCAGGAGCGGGTATTGTTTACGATTCAGATCCAGTAGCTGAATATGAAGAAACATTAAATAAAGCGAGA
GCGCTATTGGAGGTAATGAA

Downstream 100 bases:

>100_bases
ATAACTATCTTCGTAAATTAGTGGAGGGACAACATTTAACAGAAGAGGAAATGTATAAAGCGGGGCTTCTTTTATTAAAT
GAAAACATATTGGAAAGTGA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MIVLIDNYDSFTYNLYQLLGEYEEEIVVVRNDQITIEQLEEMNPKGIVLSPGPGKPEEAGICIEVIRHFYKNVPILGICL
GHQAIISAFGGEIVRAERIKHGKTSRAKHNGTSIFSYVTQPLTAMRYHSLVAAQTSLPQCFDILATAMDDGEIMAVRHNY
YPLFGLQFHPESIATEEGGKLIRAFLGEVKEEERV

Sequences:

>Translated_195_residues
MIVLIDNYDSFTYNLYQLLGEYEEEIVVVRNDQITIEQLEEMNPKGIVLSPGPGKPEEAGICIEVIRHFYKNVPILGICL
GHQAIISAFGGEIVRAERIKHGKTSRAKHNGTSIFSYVTQPLTAMRYHSLVAAQTSLPQCFDILATAMDDGEIMAVRHNY
YPLFGLQFHPESIATEEGGKLIRAFLGEVKEEERV
>Mature_195_residues
MIVLIDNYDSFTYNLYQLLGEYEEEIVVVRNDQITIEQLEEMNPKGIVLSPGPGKPEEAGICIEVIRHFYKNVPILGICL
GHQAIISAFGGEIVRAERIKHGKTSRAKHNGTSIFSYVTQPLTAMRYHSLVAAQTSLPQCFDILATAMDDGEIMAVRHNY
YPLFGLQFHPESIATEEGGKLIRAFLGEVKEEERV

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=185, Percent_Identity=28.1081081081081, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=52.6881720430108, Blast_Score=215, Evalue=2e-57,
Organism=Escherichia coli, GI1787517, Length=194, Percent_Identity=43.298969072165, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1786215, Length=141, Percent_Identity=29.7872340425532, Blast_Score=75, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322638, Length=186, Percent_Identity=46.2365591397849, Blast_Score=183, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6324361, Length=213, Percent_Identity=34.2723004694836, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 21884; Mature: 21884

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLIDNYDSFTYNLYQLLGEYEEEIVVVRNDQITIEQLEEMNPKGIVLSPGPGKPEEAG
CEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCEEHHHHHCCCCCEEEECCCCCCCCCCC
ICIEVIRHFYKNVPILGICLGHQAIISAFGGEIVRAERIKHGKTSRAKHNGTSIFSYVTQ
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
PLTAMRYHSLVAAQTSLPQCFDILATAMDDGEIMAVRHNYYPLFGLQFHPESIATEEGGK
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCHHHCCCCHHH
LIRAFLGEVKEEERV
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MIVLIDNYDSFTYNLYQLLGEYEEEIVVVRNDQITIEQLEEMNPKGIVLSPGPGKPEEAG
CEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCEEHHHHHCCCCCEEEECCCCCCCCCCC
ICIEVIRHFYKNVPILGICLGHQAIISAFGGEIVRAERIKHGKTSRAKHNGTSIFSYVTQ
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
PLTAMRYHSLVAAQTSLPQCFDILATAMDDGEIMAVRHNYYPLFGLQFHPESIATEEGGK
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCHHHCCCCHHH
LIRAFLGEVKEEERV
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]