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The map label for this gene is arlR [H]

Identifier: 49183643

GI number: 49183643

Start: 667904

End: 668581

Strand: Reverse

Name: arlR [H]

Synonym: BAS0618

Alternate gene names: 49183643

Gene position: 668581-667904 (Counterclockwise)

Preceding gene: 49183648

Following gene: 49183642

Centisome position: 12.79

GC content: 36.28

Gene sequence:

>678_bases
ATGATTGATATACTGCTCGTAGACGATGAACCGAGAATGCTTGAATTATTAACGCTTTATCTTACTCCAATTGGATATAA
CTGCATATGTGCACGATCCGGAGAAGAAGCGATTTCACATATAGAAAATCAAAACTTTAAATTTATTTTACTCGATATTA
TGATGCCAAAGATGGATGGATGGGAAACGTGCAAAAAAATCCGTTCATTTAGTAACGTTCCTATTATTATGGTTACCGCT
CGTGATCAAACCATCGATGTCGTCCAAGGATTAAAACTCGGAGCGGATGATTACGTAACGAAACCTTTCCATGAAGAAGA
GCTTTTCGCAAGAATTGAAGCTGTTTTAAGGCGAACGAATCAACACGCGCAAATCCAATATCACGGCATTTTATGGAATG
AAGCAAAGCACTCCGCTTCTGTTCATAATGAAGAGCTTCTTCTTACACCAATTGAATTCTCTTTACTCGGATTATTTTTA
CGTCATGTGAACTACGTATTGAGCCGCGATCAGCTTATTGAACGAATTTGGGGATTAAATACAAATACAGAAGATAGAAC
AGTCGATTCACATATTCGTAATTTGCGTGATAAATTACGAAAAGTAAATTTCCCTATTGATAATCATTTAAAAACTGTGT
ACGGAGTTGGTTATCGATGGATTGATATCGAACATTAA

Upstream 100 bases:

>100_bases
AGTAATTCTGAAGAAATTATGCAGACACATTACAATCTGCACCATTTCTTCATGATTTTGCATTACAATTTAAGTAAAGA
TTATATATGGAGGGCTCTCT

Downstream 100 bases:

>100_bases
GGAGCAAAGTGATGAAACGCATCTCTATTCAATTCGGATTTTATTTTTTAATTGTCACACTTTTAATTGAAAGTGTTCTA
TTTGTTTTGCTCTATTATAG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPKMDGWETCKKIRSFSNVPIIMVTA
RDQTIDVVQGLKLGADDYVTKPFHEEELFARIEAVLRRTNQHAQIQYHGILWNEAKHSASVHNEELLLTPIEFSLLGLFL
RHVNYVLSRDQLIERIWGLNTNTEDRTVDSHIRNLRDKLRKVNFPIDNHLKTVYGVGYRWIDIEH

Sequences:

>Translated_225_residues
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPKMDGWETCKKIRSFSNVPIIMVTA
RDQTIDVVQGLKLGADDYVTKPFHEEELFARIEAVLRRTNQHAQIQYHGILWNEAKHSASVHNEELLLTPIEFSLLGLFL
RHVNYVLSRDQLIERIWGLNTNTEDRTVDSHIRNLRDKLRKVNFPIDNHLKTVYGVGYRWIDIEH
>Mature_225_residues
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPKMDGWETCKKIRSFSNVPIIMVTA
RDQTIDVVQGLKLGADDYVTKPFHEEELFARIEAVLRRTNQHAQIQYHGILWNEAKHSASVHNEELLLTPIEFSLLGLFL
RHVNYVLSRDQLIERIWGLNTNTEDRTVDSHIRNLRDKLRKVNFPIDNHLKTVYGVGYRWIDIEH

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=38.4615384615385, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=38.5650224215247, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=39.1304347826087, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.5291479820628, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=34.6491228070175, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1786784, Length=219, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=31.651376146789, Blast_Score=123, Evalue=8e-30,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=33.6322869955157, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=32.7354260089686, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=35.1111111111111, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=31.1111111111111, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=29.3577981651376, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=36.6666666666667, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788550, Length=125, Percent_Identity=32.8, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=29.7520661157025, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=110, Percent_Identity=32.7272727272727, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788905, Length=117, Percent_Identity=31.6239316239316, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI145693157, Length=100, Percent_Identity=34, Blast_Score=61, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=108, Percent_Identity=32.4074074074074, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26297; Mature: 26297

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPKMDG
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCEEEEEEEECCCCCC
WETCKKIRSFSNVPIIMVTARDQTIDVVQGLKLGADDYVTKPFHEEELFARIEAVLRRTN
HHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QHAQIQYHGILWNEAKHSASVHNEELLLTPIEFSLLGLFLRHVNYVLSRDQLIERIWGLN
CCCEEEEEEEEECCCHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TNTEDRTVDSHIRNLRDKLRKVNFPIDNHLKTVYGVGYRWIDIEH
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECC
>Mature Secondary Structure
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPKMDG
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCEEEEEEEECCCCCC
WETCKKIRSFSNVPIIMVTARDQTIDVVQGLKLGADDYVTKPFHEEELFARIEAVLRRTN
HHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QHAQIQYHGILWNEAKHSASVHNEELLLTPIEFSLLGLFLRHVNYVLSRDQLIERIWGLN
CCCEEEEEEEEECCCHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TNTEDRTVDSHIRNLRDKLRKVNFPIDNHLKTVYGVGYRWIDIEH
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA