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The map label for this gene is resE [H]

Identifier: 49183642

GI number: 49183642

Start: 666501

End: 667892

Strand: Reverse

Name: resE [H]

Synonym: BAS0617

Alternate gene names: 49183642

Gene position: 667892-666501 (Counterclockwise)

Preceding gene: 49183643

Following gene: 49183640

Centisome position: 12.77

GC content: 34.34

Gene sequence:

>1392_bases
ATGAAACGCATCTCTATTCAATTCGGATTTTATTTTTTAATTGTCACACTTTTAATTGAAAGTGTTCTATTTGTTTTGCT
CTATTATAGTCTCGTAAACACTAGAGTAAATGAAGAAATGACTGCTTTATTAAAACGTGGAAACAGCCATCGTGATGTAC
TTGAAAAATATTATGATGAGCAAACAATCTCTCACGTTGCACTAATGGAATCTGAAGCTGAAACTACTGTCGTTATTACA
AATACAAATAAAGAAGTACTAGCTAAATCTAACAAAATAAACACAACTATAAAAAATCACATTAGTAGCATGCAAACACG
CACAAATCATGACGGAGCGATTATAGAGAATCACTGGAAAACATCTAATTATATATGTACGGTCAGTCCCATCATAGTAG
CTGGAAAACATGAGGGGTATGTGTATATGTTTCTTGGGACAGAATCCATTGAAAAGTTGGTAAATGGATTAACGAAACAA
TTCATTATTGCTGGTGCCATCACGTTTCTACTCACAGTCATTACCATTTTTCTTTTATCTCGGTTATTAACAAAACCATT
GTTACATATGAAACATGCCACTGAAAAAATGAGTAAAGGCGATTTATCCGTTTCGTTAACAACTACTCGAAATGATGAAA
TTGGTGAACTATCCTCATCAATTCAAACGCTTGCTAATGATTTACATTATATGAAAACAGAGCGAAGTGAATTTCTAGCA
AGTGTTGCTCATGAATTACGAACACCTTTAACATACGTAAGAGGCTACGCTGACATTGCTTTAAAAGAAACCACATCTCC
CGAGCAACGTTTACGGTATTTATCTATTATAAAAGATGAGTCTGATTACATTACAAACTTAGTTCAAGATTTATTTTCAC
TGGCACAAATGGAACAACATAACTTTTCTATTCAAGTAAAGGAAGTACATTTACACACTTTCCTTACTCGCATATCTGAA
AAAGTAAACGCCATGTATAAAGAAAGATACATTACAGTTTCTTTCTCTTGTCCTCCTACACTGCTAGTAAACTTAGATGA
ACAACGATTTGAACAAGTTGTAGTGAATATTTTAAATAACGCTTATAGACATTCAAAAGAACATTCTCAAATTCATATTT
CTGTTATAGAAGAAAATAAACGTATCTCCATTACAATGGAAGATGAAGGCGAAGGTATTCCTCCTGAAGACCTCCCTCAC
ATTTTCGAACGCTTTTATCGAGTTGATAAAGCTAGATCACGAGCTACCGGTGGGACTGGTTTAGGGCTATCTATCGTGAA
AGAAATTGTAGAACTACACGGCGGAAATATTACTGTAACGAGCGAAGTTGATCACGGGTCTTGTTTTACAATTTCCTTGC
CATCTATAAAGAAACACGACTACCATCAGTAG

Upstream 100 bases:

>100_bases
ATAAATTACGAAAAGTAAATTTCCCTATTGATAATCATTTAAAAACTGTGTACGGAGTTGGTTATCGATGGATTGATATC
GAACATTAAGGAGCAAAGTG

Downstream 100 bases:

>100_bases
TCGTGTTTCTTTATCATTTTACTTTATAATATAAGTTTACAAATTGCCCAAAACGTTTCGTATCCGTTAAAGTTAAATGG
ATTTCTGGGTTCTTGTCTTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MKRISIQFGFYFLIVTLLIESVLFVLLYYSLVNTRVNEEMTALLKRGNSHRDVLEKYYDEQTISHVALMESEAETTVVIT
NTNKEVLAKSNKINTTIKNHISSMQTRTNHDGAIIENHWKTSNYICTVSPIIVAGKHEGYVYMFLGTESIEKLVNGLTKQ
FIIAGAITFLLTVITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELSSSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRISE
KVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSQIHISVIEENKRISITMEDEGEGIPPEDLPH
IFERFYRVDKARSRATGGTGLGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKKHDYHQ

Sequences:

>Translated_463_residues
MKRISIQFGFYFLIVTLLIESVLFVLLYYSLVNTRVNEEMTALLKRGNSHRDVLEKYYDEQTISHVALMESEAETTVVIT
NTNKEVLAKSNKINTTIKNHISSMQTRTNHDGAIIENHWKTSNYICTVSPIIVAGKHEGYVYMFLGTESIEKLVNGLTKQ
FIIAGAITFLLTVITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELSSSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRISE
KVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSQIHISVIEENKRISITMEDEGEGIPPEDLPH
IFERFYRVDKARSRATGGTGLGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKKHDYHQ
>Mature_463_residues
MKRISIQFGFYFLIVTLLIESVLFVLLYYSLVNTRVNEEMTALLKRGNSHRDVLEKYYDEQTISHVALMESEAETTVVIT
NTNKEVLAKSNKINTTIKNHISSMQTRTNHDGAIIENHWKTSNYICTVSPIIVAGKHEGYVYMFLGTESIEKLVNGLTKQ
FIIAGAITFLLTVITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELSSSIQTLANDLHYMKTERSEFLA
SVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRISE
KVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSQIHISVIEENKRISITMEDEGEGIPPEDLPH
IFERFYRVDKARSRATGGTGLGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKKHDYHQ

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=277, Percent_Identity=31.4079422382672, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=32.046332046332, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1786783, Length=348, Percent_Identity=27.5862068965517, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787894, Length=286, Percent_Identity=26.5734265734266, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790346, Length=297, Percent_Identity=29.96632996633, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=31.25, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=29.2035398230088, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=27.8008298755187, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI48994928, Length=237, Percent_Identity=29.957805907173, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=30.5555555555556, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081816, Length=336, Percent_Identity=25, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788279, Length=308, Percent_Identity=28.2467532467532, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=28.6995515695067, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082128, Length=302, Percent_Identity=24.5033112582781, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790861, Length=390, Percent_Identity=22.0512820512821, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789808, Length=291, Percent_Identity=28.1786941580756, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=29.7777777777778, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789403, Length=344, Percent_Identity=27.0348837209302, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790551, Length=281, Percent_Identity=27.7580071174377, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790300, Length=254, Percent_Identity=29.5275590551181, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=299, Percent_Identity=23.0769230769231, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52772; Mature: 52772

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRISIQFGFYFLIVTLLIESVLFVLLYYSLVNTRVNEEMTALLKRGNSHRDVLEKYYDE
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QTISHVALMESEAETTVVITNTNKEVLAKSNKINTTIKNHISSMQTRTNHDGAIIENHWK
HHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCC
TSNYICTVSPIIVAGKHEGYVYMFLGTESIEKLVNGLTKQFIIAGAITFLLTVITIFLLS
CCCEEEEECEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELSSSIQTLANDLHYMKTERSEFLA
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQH
HHHHHHHCCHHHHCCHHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
NFSIQVKEVHLHTFLTRISEKVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNN
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHHHHHHHHHHH
AYRHSKEHSQIHISVIEENKRISITMEDEGEGIPPEDLPHIFERFYRVDKARSRATGGTG
HHHCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
LGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKKHDYHQ
CCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKRISIQFGFYFLIVTLLIESVLFVLLYYSLVNTRVNEEMTALLKRGNSHRDVLEKYYDE
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QTISHVALMESEAETTVVITNTNKEVLAKSNKINTTIKNHISSMQTRTNHDGAIIENHWK
HHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCC
TSNYICTVSPIIVAGKHEGYVYMFLGTESIEKLVNGLTKQFIIAGAITFLLTVITIFLLS
CCCEEEEECEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELSSSIQTLANDLHYMKTERSEFLA
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQH
HHHHHHHCCHHHHCCHHHEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
NFSIQVKEVHLHTFLTRISEKVNAMYKERYITVSFSCPPTLLVNLDEQRFEQVVVNILNN
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHHHHHHHHHHH
AYRHSKEHSQIHISVIEENKRISITMEDEGEGIPPEDLPHIFERFYRVDKARSRATGGTG
HHHCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
LGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKKHDYHQ
CCHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]