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The map label for this gene is gph [H]

Identifier: 49183337

GI number: 49183337

Start: 331349

End: 332092

Strand: Direct

Name: gph [H]

Synonym: BAS0309

Alternate gene names: 49183337

Gene position: 331349-332092 (Clockwise)

Preceding gene: 49183336

Following gene: 49183338

Centisome position: 6.34

GC content: 37.77

Gene sequence:

>744_bases
ATGGAGAAGGTAAAAGCAATACTATTTGATAAAGATGGGACATTAATGGATTTTCATTCAATTTGGATAAAAGTAGCTGA
AGAACTTGTGGCGGAATGTATCAATTTATATGAACTGCCAAAGTCAATGCAGCCTACTTTATTAAAAGAGATCGGCGTGG
AGGGGGTGTTTGTGAACCCTCGTAGCGCAATAGCGGCAGGAACAAGCCTTGATGTGGCAAAGGGGCTTTGTAAGTATATT
ACGTCATCTAAGGAAGAGGAGATGCATGAGTGGGTAAGTGAAAAGTTATTTTCCCTTATGTATGAGCACCGTTCCTATAT
GAAAATGACGGCAGATTTACCGAGAATTTTACAAAGTTTAAAGGATAGAGGATTTATTTTAGGTGTTGTGACAGCTGATG
ATTTCGCACCGACAGAATTATTTTTAAAACAGTATCAATTAGAGTCTTTTTTTGATTATGTTGTAGCTTCAGATACATTT
CCGGCACAAAAACCAGATAAAAGAATTGTAGAATCCTTCTGTGATAAGTTTCATTTAGATGCATGTGAAGTAGCGGTCGT
CGGAGATACGCCAACTGATTTACATTTAGCTAAAAATGGTGATTGCTATGCAATTGGGGTGCTATCTGGTACAGGAGATC
GTCAAACGTTAGAACCACTTGCGGATTTAGTAGTACAATCTGTTGAGGATTTTATTTCTCATTCAGGTGAGTTTATTTGG
GAACGAGGAAAGTCTAATGTGTAA

Upstream 100 bases:

>100_bases
AGTTAGTTTGATTTTCATGGTATTTTTACAATTCGTTTATTTTATATCCATACTTTATTGATACACTGGAGGAGATAAGA
GACGAGAGGTAGGGTGTGCT

Downstream 100 bases:

>100_bases
GAAAAATAAGTCTATAAAGACTCTTAATGAGTCTTTATAGACTTATTTTTTATGGCGAAATAGAAGGTGTGTAGGATGAA
TATTGGAAAAGAATGTTGGC

Product: haloacid dehalogenase/epoxide hydrolase family protein

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MEKVKAILFDKDGTLMDFHSIWIKVAEELVAECINLYELPKSMQPTLLKEIGVEGVFVNPRSAIAAGTSLDVAKGLCKYI
TSSKEEEMHEWVSEKLFSLMYEHRSYMKMTADLPRILQSLKDRGFILGVVTADDFAPTELFLKQYQLESFFDYVVASDTF
PAQKPDKRIVESFCDKFHLDACEVAVVGDTPTDLHLAKNGDCYAIGVLSGTGDRQTLEPLADLVVQSVEDFISHSGEFIW
ERGKSNV

Sequences:

>Translated_247_residues
MEKVKAILFDKDGTLMDFHSIWIKVAEELVAECINLYELPKSMQPTLLKEIGVEGVFVNPRSAIAAGTSLDVAKGLCKYI
TSSKEEEMHEWVSEKLFSLMYEHRSYMKMTADLPRILQSLKDRGFILGVVTADDFAPTELFLKQYQLESFFDYVVASDTF
PAQKPDKRIVESFCDKFHLDACEVAVVGDTPTDLHLAKNGDCYAIGVLSGTGDRQTLEPLADLVVQSVEDFISHSGEFIW
ERGKSNV
>Mature_247_residues
MEKVKAILFDKDGTLMDFHSIWIKVAEELVAECINLYELPKSMQPTLLKEIGVEGVFVNPRSAIAAGTSLDVAKGLCKYI
TSSKEEEMHEWVSEKLFSLMYEHRSYMKMTADLPRILQSLKDRGFILGVVTADDFAPTELFLKQYQLESFFDYVVASDTF
PAQKPDKRIVESFCDKFHLDACEVAVVGDTPTDLHLAKNGDCYAIGVLSGTGDRQTLEPLADLVVQSVEDFISHSGEFIW
ERGKSNV

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 27732; Mature: 27732

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVKAILFDKDGTLMDFHSIWIKVAEELVAECINLYELPKSMQPTLLKEIGVEGVFVNP
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECC
RSAIAAGTSLDVAKGLCKYITSSKEEEMHEWVSEKLFSLMYEHRSYMKMTADLPRILQSL
HHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDRGFILGVVTADDFAPTELFLKQYQLESFFDYVVASDTFPAQKPDKRIVESFCDKFHLD
HCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
ACEVAVVGDTPTDLHLAKNGDCYAIGVLSGTGDRQTLEPLADLVVQSVEDFISHSGEFIW
CEEEEEECCCCCCEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEE
ERGKSNV
CCCCCCC
>Mature Secondary Structure
MEKVKAILFDKDGTLMDFHSIWIKVAEELVAECINLYELPKSMQPTLLKEIGVEGVFVNP
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECC
RSAIAAGTSLDVAKGLCKYITSSKEEEMHEWVSEKLFSLMYEHRSYMKMTADLPRILQSL
HHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDRGFILGVVTADDFAPTELFLKQYQLESFFDYVVASDTFPAQKPDKRIVESFCDKFHLD
HCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
ACEVAVVGDTPTDLHLAKNGDCYAIGVLSGTGDRQTLEPLADLVVQSVEDFISHSGEFIW
CEEEEEECCCCCCEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEE
ERGKSNV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]