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The map label for this gene is ycbM [H]

Identifier: 49183301

GI number: 49183301

Start: 287877

End: 288899

Strand: Reverse

Name: ycbM [H]

Synonym: BAS0272

Alternate gene names: 49183301

Gene position: 288899-287877 (Counterclockwise)

Preceding gene: 49183302

Following gene: 49183300

Centisome position: 5.53

GC content: 33.33

Gene sequence:

>1023_bases
GTGAAAAGCTTGAAGATTGATAAAATCCTCTTCCTTATTTCATTACAACTTATCATTTACGGGCTTTTACATATACAAAT
GGATCCAAAAGTAAAAATTTCTTTATTTATTACCCTTATCTTAATTACAATGTATCTCTTCTTTTCAAGAATACAATTTA
TTCAAAATCACAAATCAATAGACACTAAATTAAGTCGTGCACTAAAGGGGAATTTACAAACGAGATTATTCACAAGTAAT
GATCAATCGTTACATAATATCGTTTTTTCAATAAACGAACTAATAACTGAATTAGAAAAGGTTCGGATTAAAGCAAAAAG
GTCTGAGGAATCTAGAAAACAACTTTTATCTAGTATCTCACACGATATCCGAACACCACTCACCTCCATTATTGGATATA
TCGACGCTTTAAAAGATGGGGTTGCTGCTTCTGAAATAGAAAAGCAAGAATATCTTAAAATACTTTATATGAAATCAAAT
AACTTAAAGCACCTAGTTGATGAAATATTCAATATGGCAAAGCTAGACGCTAATGAATTTCCACTAAAAGAAGAAAAACT
CGACTTTTCTGAAGTTACTAGAGAAGTTTTGATCGATTTTTTACCTGAAATCTCAAAACATAATATTAAACTGCAAGTTC
TTATGCCAGAGTCTACTTGTCCTATCATTGCAGATCACCTAAGCCTTATGCGGATTATAGGTAATTTAATGAAAAATGCC
ATTTATTACGGAAAGGATGGGAAAACAATAGGAGTCGAACTACTAGAAACGGATGCAGCATATGAACTTCTTATTTGGGA
CAAAGGCCCTGGTATTCCAAAACATGATTTACAAAACGTATTTGAGCGAATGTACCGAAGCGAACAATCAAGAAACTCGT
CTTTTGGTGGTAGTGGGCTCGGCCTTTCTATTTCTAAAGCGCTCGTTGAGAAGAATGGTGGGCATATATGGGTTGAAAGT
ATTCCATGGGAACGAACCACTTTTGGCTTTTCCATTCCAAAACACAATACTTTTAAGAAATAG

Upstream 100 bases:

>100_bases
GTTATGGTACATATTCGAAAACTTAGAAAGAAAATAGAAATCGATCCTTCCAATCCAAAATTCATTCAAACTGTATGGGG
AATTGGCTATAAGTTTGTAG

Downstream 100 bases:

>100_bases
TTAAGAAATGATTAATATGCAGTTAAGCCTTCCTTTTTATCATGTAAGTAAGAACTTATAGAAAGTGGGTGTCTCCTATA
AACACAATTATAAAAACGAC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKSLKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSN
DQSLHNIVFSINELITELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSN
NLKHLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNA
IYYGKDGKTIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVES
IPWERTTFGFSIPKHNTFKK

Sequences:

>Translated_340_residues
MKSLKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSN
DQSLHNIVFSINELITELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSN
NLKHLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNA
IYYGKDGKTIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVES
IPWERTTFGFSIPKHNTFKK
>Mature_340_residues
MKSLKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSN
DQSLHNIVFSINELITELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSN
NLKHLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNA
IYYGKDGKTIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVES
IPWERTTFGFSIPKHNTFKK

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=28.030303030303, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1786912, Length=274, Percent_Identity=27.3722627737226, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=30.8270676691729, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=28.5140562248996, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=28.6885245901639, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=24.7899159663866, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=27.6315789473684, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786783, Length=239, Percent_Identity=26.7782426778243, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787894, Length=290, Percent_Identity=25.5172413793103, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790346, Length=267, Percent_Identity=25.4681647940075, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082128, Length=312, Percent_Identity=24.0384615384615, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=247, Percent_Identity=24.2914979757085, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=28.0851063829787, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=304, Percent_Identity=21.7105263157895, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=24.8888888888889, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38981; Mature: 38981

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNHKSI
CCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTKLSRALKGNLQTRLFTSNDQSLHNIVFSINELITELEKVRIKAKRSEESRKQLLSSIS
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCC
PLKEEKLDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNA
CCCHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
IYYGKDGKTIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGL
EEECCCCCEEEHEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
GLSISKALVEKNGGHIWVESIPWERTTFGFSIPKHNTFKK
CHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MKSLKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNHKSI
CCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTKLSRALKGNLQTRLFTSNDQSLHNIVFSINELITELEKVRIKAKRSEESRKQLLSSIS
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEF
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCC
PLKEEKLDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNA
CCCHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
IYYGKDGKTIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGL
EEECCCCCEEEHEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
GLSISKALVEKNGGHIWVESIPWERTTFGFSIPKHNTFKK
CHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]