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The map label for this gene is ycbL [H]

Identifier: 49183302

GI number: 49183302

Start: 288880

End: 289593

Strand: Reverse

Name: ycbL [H]

Synonym: BAS0273

Alternate gene names: 49183302

Gene position: 289593-288880 (Counterclockwise)

Preceding gene: 49183315

Following gene: 49183301

Centisome position: 5.54

GC content: 32.07

Gene sequence:

>714_bases
ATGAAAGATATACGTATCCTTATAGCAGATGATGATAAAGAAATCCGTAATTTACTAAAAATATATTTAGAACGAGAATT
ATATATGGTAGATACTGCGATTGATGGCGAAGTAGCCTTACAGTTATTTAATCAAAACAACTATAGCATCGTTATATTAG
ATCTTATGATGCCAAAAGTAGATGGTATCGAAGTATGTAGAAAGCTTAGAGATAAAACTAACGTACCGATATTAATGCTA
ACCGCTAAAGATCACGAAGTCGATAAAATTTTAGGTTTAAGCATTGGTGCTGATGATTACATTACGAAGCCTTTCAGCAT
TCACGAAGTAGTTGCACGAGTCAAAGCTCTTATACGGCGTTTTTTAGTTCTTGGAAGTAACATTAATGTACAAGAGAAGA
CAACTTTAGCTTTTAAAGGACTAACTATCAATTTAAATACATATACAGTTCACACAAATAAAGAAGAAATCAGCTTAACC
GGAAAAGAACTAGAACTATTAAAATTCTTTACTTCAAACCCAGGACAAGTATTTACAAAAACACAGCTCTTTCGCAATGT
ATGGGACGATAATTATATAGAAGATGATAATACCGTTATGGTACATATTCGAAAACTTAGAAAGAAAATAGAAATCGATC
CTTCCAATCCAAAATTCATTCAAACTGTATGGGGAATTGGCTATAAGTTTGTAGGTGAAAAGCTTGAAGATTGA

Upstream 100 bases:

>100_bases
TCCCTTCCCTAAAACTATTAACCTTATTTTAACAAATACTAGTATATAATTAGAGGGTTGTTGTACCATCAATGAAAATC
TATTAGAAGCAGGTGAAGAT

Downstream 100 bases:

>100_bases
TAAAATCCTCTTCCTTATTTCATTACAACTTATCATTTACGGGCTTTTACATATACAAATGGATCCAAAAGTAAAAATTT
CTTTATTTATTACCCTTATC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAIDGEVALQLFNQNNYSIVILDLMMPKVDGIEVCRKLRDKTNVPILML
TAKDHEVDKILGLSIGADDYITKPFSIHEVVARVKALIRRFLVLGSNINVQEKTTLAFKGLTINLNTYTVHTNKEEISLT
GKELELLKFFTSNPGQVFTKTQLFRNVWDDNYIEDDNTVMVHIRKLRKKIEIDPSNPKFIQTVWGIGYKFVGEKLED

Sequences:

>Translated_237_residues
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAIDGEVALQLFNQNNYSIVILDLMMPKVDGIEVCRKLRDKTNVPILML
TAKDHEVDKILGLSIGADDYITKPFSIHEVVARVKALIRRFLVLGSNINVQEKTTLAFKGLTINLNTYTVHTNKEEISLT
GKELELLKFFTSNPGQVFTKTQLFRNVWDDNYIEDDNTVMVHIRKLRKKIEIDPSNPKFIQTVWGIGYKFVGEKLED
>Mature_237_residues
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAIDGEVALQLFNQNNYSIVILDLMMPKVDGIEVCRKLRDKTNVPILML
TAKDHEVDKILGLSIGADDYITKPFSIHEVVARVKALIRRFLVLGSNINVQEKTTLAFKGLTINLNTYTVHTNKEEISLT
GKELELLKFFTSNPGQVFTKTQLFRNVWDDNYIEDDNTVMVHIRKLRKKIEIDPSNPKFIQTVWGIGYKFVGEKLED

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=38.0952380952381, Blast_Score=184, Evalue=3e-48,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=37.6106194690265, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=36.6812227074236, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790863, Length=240, Percent_Identity=36.25, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=35.4978354978355, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=35.3982300884956, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=36.283185840708, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=34.7826086956522, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=34.7639484978541, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=34.2105263157895, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=33.0472103004292, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789402, Length=234, Percent_Identity=34.1880341880342, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=31.1111111111111, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=31.7796610169492, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=40, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27375; Mature: 27375

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAIDGEVALQLFNQNNYSIVILDLMMPKV
CCCEEEEEECCCHHHHHHHHHHHHCEEEEEEEECCCCEEEEEECCCCCEEEEEEEECCCC
DGIEVCRKLRDKTNVPILMLTAKDHEVDKILGLSIGADDYITKPFSIHEVVARVKALIRR
CHHHHHHHHHHCCCCCEEEEEECCCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
FLVLGSNINVQEKTTLAFKGLTINLNTYTVHTNKEEISLTGKELELLKFFTSNPGQVFTK
HHHHCCCCCCCCCEEEEEEEEEEEEEEEEEECCCCEEEECCCCEEEHHHHHCCCCCCHHH
TQLFRNVWDDNYIEDDNTVMVHIRKLRKKIEIDPSNPKFIQTVWGIGYKFVGEKLED
HHHHHHHCCCCCCCCCCEEEEEEHHHHHHEECCCCCCHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAIDGEVALQLFNQNNYSIVILDLMMPKV
CCCEEEEEECCCHHHHHHHHHHHHCEEEEEEEECCCCEEEEEECCCCCEEEEEEEECCCC
DGIEVCRKLRDKTNVPILMLTAKDHEVDKILGLSIGADDYITKPFSIHEVVARVKALIRR
CHHHHHHHHHHCCCCCEEEEEECCCCCHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
FLVLGSNINVQEKTTLAFKGLTINLNTYTVHTNKEEISLTGKELELLKFFTSNPGQVFTK
HHHHCCCCCCCCCEEEEEEEEEEEEEEEEEECCCCEEEECCCCEEEHHHHHCCCCCCHHH
TQLFRNVWDDNYIEDDNTVMVHIRKLRKKIEIDPSNPKFIQTVWGIGYKFVGEKLED
HHHHHHHCCCCCCCCCCEEEEEEHHHHHHEECCCCCCHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]