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The map label for this gene is pabB [H]

Identifier: 46446961

GI number: 46446961

Start: 1583393

End: 1584697

Strand: Reverse

Name: pabB [H]

Synonym: pc1327

Alternate gene names: 46446961

Gene position: 1584697-1583393 (Counterclockwise)

Preceding gene: 46446962

Following gene: 46446960

Centisome position: 65.63

GC content: 34.33

Gene sequence:

>1305_bases
TTGCTTTTTTCTGGAGGCGAATTTGACTCCTCTGAGCATTCTTTTTTATCTCTTTTTCCGATTGAAATTGTAATTGCAAA
AGATCGGCAAGTGATCCATAAAACAAAGCAACAGATTTTCCAGCAAGAGATAAAAAATCCTTGGGAAGCTCTTCAAAAAT
TTTTTTTTGATTCGTTAGAAAATAACTCTGAAAACTACGCTTTTGGATTTTTCGGTTATGAAATGGGATTTTCCTCCGAT
CCTGATGTACAATTATTTTGCCAATCTCATGAATGGACACCTGATGCCATGTGGCAAAAATGCGCAATTACAATTATCTA
TAACCATTCTAACCAACAGGCTATCCTTAAAATAGCTGATTTTACTGACCAAACACTAAACCCTTTACATCAACATTGGG
TTAAAAAACTTTCTGATAAAAATTGGTGGGAAAGTGATAGCTTTAATTTTTTTTCCCGAACTTCACAAAAAACAGAAGCT
CAATTAAAAAACTTTTCTCTTTCAAATCGTCAACTTACTTATTTAAAGATGATTGATGAGGCAAAAGAGTGGATTTTTTC
GGGACATGTTTACCAAATTAATTTATCCCAAGAATTTACATTTGAAGGTGTTCCGCGACCTTTTGACGTCTTTCGTCAAT
TAATAGAAATCAATCCCGCTCCCTTTTCCGCTTATTTGAAAGCAGATTATTATACAATTGTATCAAGCTCTCCTGAAAGG
TTTTTGCAAAAAAAGGAAAGGCTATTAGAAACGCGCCCAATTAAAGGAACAATACAAAGAGGTGGGTATTTTGAAGAAGA
TCAATTGTTCAAAGAAAGATTACTATCATCTGAAAAAGAAAAAGCTGAGCTGTTAATGATTACAGATTTAATGCGCAATG
ATTTAGGTAAAATCAGTGAAATTGGCAGTGTTAAAACGGTTGATTTGTGGCGTTGTGAGGCCTATACGAACGTATATCAC
TTGATTTCAATTATTCGTGCTATTGCTTTAAAGCATCTAAAACCTTTAGAAATTATCCGTAGCGCATTTCCAGGTGGCTC
TATTACCGGTTGTCCCAAATTGAAAGCGATGGAATGTATACAAAAATTAGAAAATCGTTCGCGGGGTATTTATACGGGTT
CGATGGGATATATGACAGGAAAAGGAGATTTTGATTTGAATATTGCGATTCGAACTTTGGTATTTAAAGACAATTACATT
AGCTTCCAAGTGGGAGGTGGAATTGTTATCGATTCTGATCCAATTAATGAATATGCAGAAACTCTTTTTAAGGGTGACTC
ATTATTTCGAGTACTAAAGACTTAA

Upstream 100 bases:

>100_bases
TTGGTATAAGATGCTTAATTCTTTTATCTTACCTTCATTTTTTCAAAAAGATCTATTATTAGCTGTTGCAGATTTTTTTG
CGGAGTTTGAAGGAACTTGC

Downstream 100 bases:

>100_bases
ATGCATTTAAGTCTTTGCATTTAAAATGCAGAAAAATAAAATTTGTTTATTAATTCAATCAAATAGTAAGATTCAACAAA
CTTTTAGATTGTTTGAAGTA

Product: putative para-aminobenzoate synthase component I

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MLFSGGEFDSSEHSFLSLFPIEIVIAKDRQVIHKTKQQIFQQEIKNPWEALQKFFFDSLENNSENYAFGFFGYEMGFSSD
PDVQLFCQSHEWTPDAMWQKCAITIIYNHSNQQAILKIADFTDQTLNPLHQHWVKKLSDKNWWESDSFNFFSRTSQKTEA
QLKNFSLSNRQLTYLKMIDEAKEWIFSGHVYQINLSQEFTFEGVPRPFDVFRQLIEINPAPFSAYLKADYYTIVSSSPER
FLQKKERLLETRPIKGTIQRGGYFEEDQLFKERLLSSEKEKAELLMITDLMRNDLGKISEIGSVKTVDLWRCEAYTNVYH
LISIIRAIALKHLKPLEIIRSAFPGGSITGCPKLKAMECIQKLENRSRGIYTGSMGYMTGKGDFDLNIAIRTLVFKDNYI
SFQVGGGIVIDSDPINEYAETLFKGDSLFRVLKT

Sequences:

>Translated_434_residues
MLFSGGEFDSSEHSFLSLFPIEIVIAKDRQVIHKTKQQIFQQEIKNPWEALQKFFFDSLENNSENYAFGFFGYEMGFSSD
PDVQLFCQSHEWTPDAMWQKCAITIIYNHSNQQAILKIADFTDQTLNPLHQHWVKKLSDKNWWESDSFNFFSRTSQKTEA
QLKNFSLSNRQLTYLKMIDEAKEWIFSGHVYQINLSQEFTFEGVPRPFDVFRQLIEINPAPFSAYLKADYYTIVSSSPER
FLQKKERLLETRPIKGTIQRGGYFEEDQLFKERLLSSEKEKAELLMITDLMRNDLGKISEIGSVKTVDLWRCEAYTNVYH
LISIIRAIALKHLKPLEIIRSAFPGGSITGCPKLKAMECIQKLENRSRGIYTGSMGYMTGKGDFDLNIAIRTLVFKDNYI
SFQVGGGIVIDSDPINEYAETLFKGDSLFRVLKT
>Mature_434_residues
MLFSGGEFDSSEHSFLSLFPIEIVIAKDRQVIHKTKQQIFQQEIKNPWEALQKFFFDSLENNSENYAFGFFGYEMGFSSD
PDVQLFCQSHEWTPDAMWQKCAITIIYNHSNQQAILKIADFTDQTLNPLHQHWVKKLSDKNWWESDSFNFFSRTSQKTEA
QLKNFSLSNRQLTYLKMIDEAKEWIFSGHVYQINLSQEFTFEGVPRPFDVFRQLIEINPAPFSAYLKADYYTIVSSSPER
FLQKKERLLETRPIKGTIQRGGYFEEDQLFKERLLSSEKEKAELLMITDLMRNDLGKISEIGSVKTVDLWRCEAYTNVYH
LISIIRAIALKHLKPLEIIRSAFPGGSITGCPKLKAMECIQKLENRSRGIYTGSMGYMTGKGDFDLNIAIRTLVFKDNYI
SFQVGGGIVIDSDPINEYAETLFKGDSLFRVLKT

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=371, Percent_Identity=36.6576819407008, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1787518, Length=261, Percent_Identity=32.5670498084291, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786809, Length=301, Percent_Identity=24.2524916943522, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320935, Length=362, Percent_Identity=29.2817679558011, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=421, Percent_Identity=25.8907363420428, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 50271; Mature: 50271

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFSGGEFDSSEHSFLSLFPIEIVIAKDRQVIHKTKQQIFQQEIKNPWEALQKFFFDSLE
CCCCCCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
NNSENYAFGFFGYEMGFSSDPDVQLFCQSHEWTPDAMWQKCAITIIYNHSNQQAILKIAD
CCCCCEEEEEEEEECCCCCCCCEEEEECCCCCCHHHHHCCEEEEEEEECCCCEEEEEEEC
FTDQTLNPLHQHWVKKLSDKNWWESDSFNFFSRTSQKTEAQLKNFSLSNRQLTYLKMIDE
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCEEHHHHHHHH
AKEWIFSGHVYQINLSQEFTFEGVPRPFDVFRQLIEINPAPFSAYLKADYYTIVSSSPER
HHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCHHH
FLQKKERLLETRPIKGTIQRGGYFEEDQLFKERLLSSEKEKAELLMITDLMRNDLGKISE
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IGSVKTVDLWRCEAYTNVYHLISIIRAIALKHLKPLEIIRSAFPGGSITGCPKLKAMECI
CCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHH
QKLENRSRGIYTGSMGYMTGKGDFDLNIAIRTLVFKDNYISFQVGGGIVIDSDPINEYAE
HHHHHCCCCEEECCCCCEECCCCEEEEEEEEEEEEECCEEEEEECCEEEECCCCHHHHHH
TLFKGDSLFRVLKT
HHHCCCHHHHHHCC
>Mature Secondary Structure
MLFSGGEFDSSEHSFLSLFPIEIVIAKDRQVIHKTKQQIFQQEIKNPWEALQKFFFDSLE
CCCCCCCCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
NNSENYAFGFFGYEMGFSSDPDVQLFCQSHEWTPDAMWQKCAITIIYNHSNQQAILKIAD
CCCCCEEEEEEEEECCCCCCCCEEEEECCCCCCHHHHHCCEEEEEEEECCCCEEEEEEEC
FTDQTLNPLHQHWVKKLSDKNWWESDSFNFFSRTSQKTEAQLKNFSLSNRQLTYLKMIDE
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCEEHHHHHHHH
AKEWIFSGHVYQINLSQEFTFEGVPRPFDVFRQLIEINPAPFSAYLKADYYTIVSSSPER
HHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCHHH
FLQKKERLLETRPIKGTIQRGGYFEEDQLFKERLLSSEKEKAELLMITDLMRNDLGKISE
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IGSVKTVDLWRCEAYTNVYHLISIIRAIALKHLKPLEIIRSAFPGGSITGCPKLKAMECI
CCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHH
QKLENRSRGIYTGSMGYMTGKGDFDLNIAIRTLVFKDNYISFQVGGGIVIDSDPINEYAE
HHHHHCCCCEEECCCCCEECCCCEEEEEEEEEEEEECCEEEEEECCEEEECCCCHHHHHH
TLFKGDSLFRVLKT
HHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]