BacMap

Definition	Candidatus Protochlamydia amoebophila UWE25, complete genome.
Accession	NC_005861
Length	2,414,465

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The map label for this gene is ftsH

Identifier: 46446274

GI number: 46446274

Start: 784324

End: 787074

Strand: Direct

Name: ftsH

Synonym: pc0640

Alternate gene names: 46446274

Gene position: 784324-787074 (Clockwise)

Preceding gene: 46446273

Following gene: 46446281

Centisome position: 32.48

GC content: 38.89

Gene sequence:

>2751_bases
ATGTCAGACGATAACAAGCAAGATTTTAAAAAGGGAATTTCAAACAGCTTTGTTTGGTTTCTCATGGCCGCCTTTTTGTT
TGCCTTAATGGTACAAAATTTTATTGATACCAAATTTGCCAAAGTGTCTTTTAGCTATCAGTTAGAACATTTAGTCAATT
TACAGCTTTTACAACCGGAAGATAGTCGTAAAATTGCTTTAAATGACAATTTGGTGACTTTCAGCGGTAAATTTAGAGAT
AGGCTGACAGAAGAAGGGAAAACGCGTTATAAATACTTAGAGTTACTTGACACGAATCATGAACTTAAAGCTGAACAAGC
ACGTGTTAAAGATGAAATTAAAACTCTGAAAACAAAAGTTTTCGATTCTGCTAGTTTGTTTTTGCAATTAAGCGGCTTAT
CGATTCCTAAGGGGGGATATGTTGTTGTCGATGACATGTACAATACTCCCGAAGAAGATCAGAGTGTGGTTATTAAAGAT
TTACCGAAGTCTGCTGTCGAAAGTTTGGTTAGCTTGGAAAAAGAATATGAAGCTGCCCGACAAAATCCAACGGCAGAGTC
TTTAAAAAATTTAGGTAACTTAATCAATGAACTTTTAAGAAATTTGCGTTCGCCCGCTCTTGGAATTGGATCTGAAACAA
TTAAGCAATCCCTTAAAGGAATTGATAAAGAAGTGGCAGATAGTGGAGCAACTTCTTTATCTGAACAATTAGCTGCTTAT
GGTCATGCTTTAGTTAACCTAAAAGCTATTATTGATGAATTAAATCATGAAGAGGATCACATTCGTTTAGCCAAACTACG
AAGTGTTCGTAATTATAAAGAAACGTTGGATGAATATAATCAAATCAACACACGCTTAGACGATAATCAAATTCAGTTAG
ACAAGGCTCGTCAATCCGTATCGAATGTTATTTGGTATTTTAACAATCAAGAGCTTTCAACAAAAGCTTTAGAAAAACAA
GATCCTGAAGTTTACAATCAATGGTTTAGCAAAGCTAAAGAAGAGTGGGCTAATTTTAGCCACAATCGAGGAGGCATTTT
TAGAGCCCCAGATCAACCTCTTAACGCTGTCCTTGAAAAAACCTTCAAAAGCGAAGAACCTTCTCCAAATTATTTTAGCT
ACTTGTTTACCTTATTACCTGTTTTATTAGTAATTTTAGTTTTGTATATGCTTTTTGCAAGGCAAATGAAGGGAATGGGT
AATACGGCAATGAATTTTGGAAAATCTCCAGCCCGGCTTCTCAATAAGGGAGATAACAAAATTACATTCAAGGATGTAGC
TGGAGTAGATGAAGCATTAGAAGAACTTCAAGAGATTGTAGAGTTCTTAAAGAACCCTCAAAAATTTACTTCGCTTGGTG
GTAAAATTCCAAAAGGCGTTTTATGCATTGGACCTCCAGGAACAGGTAAAACATTGATAGCAAAGGCTGTAGCTGGGGAA
GCCGACCGCCCATTCTTTTCTATTTCAGGTTCCGACTTCGTAGAAATGTTTGTAGGAGTAGGAGCGAGTCGAATTCGAGA
TCTATTCGAACAAGCAAAAAAAGCGGCTCCTTGTATCATCTTCATGGATGAAATTGATGCTGTGGGCCGCCACCGCGGAG
TTGGAATGGGCGGAGGTCACGACGAACGAGAGCAAACATTAAACCAACTTCTTGTTGAAATGGATGGTTTTGACACGAAT
GAAGGTGTTATTTTAATGGCTGCGACTAATCGTCCAGATGTATTAGACAAAGCGTTATTACGTCCAGGCCGTTTTGACAG
ACGAGTCATTATTGGATTACCAGATATTAAAGGTCGTTATGACATTTTAAAGGTTCATGCTCGACGCATTAAAATGGATC
CTTCAATCGATTTAATGGCAATTGCACGCAGCACCCCAGGTTCTTCTGGAGCTGATTTGGCAAATATATTGAATGAATCT
GCTTTACTTGCTGCTCGTAAAGGAAGGACAGCTGTCACTGCGCAGGAAACGATTGAAGCTCGTGACAAAGTTTTGTATGG
AAAAGAGCGGCGAAGCTTAGAAATCGATGAAAATGAAAAAAGAACAACAGCTTACCATGAATCAGGCCATACTGTTGTCG
GATTAATTGTGAAAAGCGGAGATCCTGTCGATAAAGTGACCATCATACCTAGAGGAATGTCTTTAGGGGCAACTATGTTT
CTTCCTAAAAAAAATCGTGTGAGCTATTGGAAACAAGAACTGCATGATCAACTTGCTGTCTTGATGGGTGGACGTGTCGC
CGAAGAAATTTTTGTCGGAGATGTGTCTAGCGGCGCTCAACAAGACATTGAACGGGCAACGCAATTAGCTCGCAGTATGG
TTTGCAAGTGGGGTATGAGCGATAAATTAGGTGCTGTTGCTTATGATGAACGTTCGGAAGGTGGCGGTCAATATGGCTTT
GGTGATCATCACGAGAAAACTTATTCTGATGAAACTGCGCAAGCTATTGATTCCGAAGTCCGCCGTATTTTAGACGAAGC
ACTTGCTATTGCCCGTAAAATTATTTTGGATTATAAAGAACAGGTCGAGTTATTAACTCTGATGTTGATTGAGTTTGAAA
CACTTGACAGTGAAGATATCCAAGAAATTGTGGTTAAAAATAACTGGGATGCCGTTCGTAAACGTGAAAGATTAAAACGC
GCAGCAGATTTACATAAAAAAGAAGCTGCTACACCACCACCTCCTCCTCCCAGAGAGGTTGATATTTCTAGTTCCGGAAC
AATACCGAACACTTTAGGATTGTCTTCTTAA

Upstream 100 bases:

>100_bases
TACTTCCTGTGGTAGAATGAACAAACCAATGCAATTATTAGTACAGACTTTTTCTAGATAGTGATTGAGAAAAGGTCGTC
AAATCGAATGTTAGGAAATT

Downstream 100 bases:

>100_bases
GAAGGGCTATCTCTTTTCTTTAAACCCTAACCACTCTATGGTTAGGGTTTTTTATTTCCGCTAATAAATCTATGCTTTAA
GTGGTAAAAATTTTTATTTT

Product: cell division protein FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 916; Mature: 915

Protein sequence:

>916_residues
MSDDNKQDFKKGISNSFVWFLMAAFLFALMVQNFIDTKFAKVSFSYQLEHLVNLQLLQPEDSRKIALNDNLVTFSGKFRD
RLTEEGKTRYKYLELLDTNHELKAEQARVKDEIKTLKTKVFDSASLFLQLSGLSIPKGGYVVVDDMYNTPEEDQSVVIKD
LPKSAVESLVSLEKEYEAARQNPTAESLKNLGNLINELLRNLRSPALGIGSETIKQSLKGIDKEVADSGATSLSEQLAAY
GHALVNLKAIIDELNHEEDHIRLAKLRSVRNYKETLDEYNQINTRLDDNQIQLDKARQSVSNVIWYFNNQELSTKALEKQ
DPEVYNQWFSKAKEEWANFSHNRGGIFRAPDQPLNAVLEKTFKSEEPSPNYFSYLFTLLPVLLVILVLYMLFARQMKGMG
NTAMNFGKSPARLLNKGDNKITFKDVAGVDEALEELQEIVEFLKNPQKFTSLGGKIPKGVLCIGPPGTGKTLIAKAVAGE
ADRPFFSISGSDFVEMFVGVGASRIRDLFEQAKKAAPCIIFMDEIDAVGRHRGVGMGGGHDEREQTLNQLLVEMDGFDTN
EGVILMAATNRPDVLDKALLRPGRFDRRVIIGLPDIKGRYDILKVHARRIKMDPSIDLMAIARSTPGSSGADLANILNES
ALLAARKGRTAVTAQETIEARDKVLYGKERRSLEIDENEKRTTAYHESGHTVVGLIVKSGDPVDKVTIIPRGMSLGATMF
LPKKNRVSYWKQELHDQLAVLMGGRVAEEIFVGDVSSGAQQDIERATQLARSMVCKWGMSDKLGAVAYDERSEGGGQYGF
GDHHEKTYSDETAQAIDSEVRRILDEALAIARKIILDYKEQVELLTLMLIEFETLDSEDIQEIVVKNNWDAVRKRERLKR
AADLHKKEAATPPPPPPREVDISSSGTIPNTLGLSS

Sequences:

>Translated_916_residues
MSDDNKQDFKKGISNSFVWFLMAAFLFALMVQNFIDTKFAKVSFSYQLEHLVNLQLLQPEDSRKIALNDNLVTFSGKFRD
RLTEEGKTRYKYLELLDTNHELKAEQARVKDEIKTLKTKVFDSASLFLQLSGLSIPKGGYVVVDDMYNTPEEDQSVVIKD
LPKSAVESLVSLEKEYEAARQNPTAESLKNLGNLINELLRNLRSPALGIGSETIKQSLKGIDKEVADSGATSLSEQLAAY
GHALVNLKAIIDELNHEEDHIRLAKLRSVRNYKETLDEYNQINTRLDDNQIQLDKARQSVSNVIWYFNNQELSTKALEKQ
DPEVYNQWFSKAKEEWANFSHNRGGIFRAPDQPLNAVLEKTFKSEEPSPNYFSYLFTLLPVLLVILVLYMLFARQMKGMG
NTAMNFGKSPARLLNKGDNKITFKDVAGVDEALEELQEIVEFLKNPQKFTSLGGKIPKGVLCIGPPGTGKTLIAKAVAGE
ADRPFFSISGSDFVEMFVGVGASRIRDLFEQAKKAAPCIIFMDEIDAVGRHRGVGMGGGHDEREQTLNQLLVEMDGFDTN
EGVILMAATNRPDVLDKALLRPGRFDRRVIIGLPDIKGRYDILKVHARRIKMDPSIDLMAIARSTPGSSGADLANILNES
ALLAARKGRTAVTAQETIEARDKVLYGKERRSLEIDENEKRTTAYHESGHTVVGLIVKSGDPVDKVTIIPRGMSLGATMF
LPKKNRVSYWKQELHDQLAVLMGGRVAEEIFVGDVSSGAQQDIERATQLARSMVCKWGMSDKLGAVAYDERSEGGGQYGF
GDHHEKTYSDETAQAIDSEVRRILDEALAIARKIILDYKEQVELLTLMLIEFETLDSEDIQEIVVKNNWDAVRKRERLKR
AADLHKKEAATPPPPPPREVDISSSGTIPNTLGLSS
>Mature_915_residues
SDDNKQDFKKGISNSFVWFLMAAFLFALMVQNFIDTKFAKVSFSYQLEHLVNLQLLQPEDSRKIALNDNLVTFSGKFRDR
LTEEGKTRYKYLELLDTNHELKAEQARVKDEIKTLKTKVFDSASLFLQLSGLSIPKGGYVVVDDMYNTPEEDQSVVIKDL
PKSAVESLVSLEKEYEAARQNPTAESLKNLGNLINELLRNLRSPALGIGSETIKQSLKGIDKEVADSGATSLSEQLAAYG
HALVNLKAIIDELNHEEDHIRLAKLRSVRNYKETLDEYNQINTRLDDNQIQLDKARQSVSNVIWYFNNQELSTKALEKQD
PEVYNQWFSKAKEEWANFSHNRGGIFRAPDQPLNAVLEKTFKSEEPSPNYFSYLFTLLPVLLVILVLYMLFARQMKGMGN
TAMNFGKSPARLLNKGDNKITFKDVAGVDEALEELQEIVEFLKNPQKFTSLGGKIPKGVLCIGPPGTGKTLIAKAVAGEA
DRPFFSISGSDFVEMFVGVGASRIRDLFEQAKKAAPCIIFMDEIDAVGRHRGVGMGGGHDEREQTLNQLLVEMDGFDTNE
GVILMAATNRPDVLDKALLRPGRFDRRVIIGLPDIKGRYDILKVHARRIKMDPSIDLMAIARSTPGSSGADLANILNESA
LLAARKGRTAVTAQETIEARDKVLYGKERRSLEIDENEKRTTAYHESGHTVVGLIVKSGDPVDKVTIIPRGMSLGATMFL
PKKNRVSYWKQELHDQLAVLMGGRVAEEIFVGDVSSGAQQDIERATQLARSMVCKWGMSDKLGAVAYDERSEGGGQYGFG
DHHEKTYSDETAQAIDSEVRRILDEALAIARKIILDYKEQVELLTLMLIEFETLDSEDIQEIVVKNNWDAVRKRERLKRA
ADLHKKEAATPPPPPPREVDISSSGTIPNTLGLSS

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=502, Percent_Identity=47.2111553784861, Blast_Score=465, Evalue=1e-131,
Organism=Homo sapiens, GI21327685, Length=492, Percent_Identity=46.5447154471545, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI7657689, Length=492, Percent_Identity=46.5447154471545, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI4507173, Length=448, Percent_Identity=42.6339285714286, Blast_Score=368, Evalue=1e-101,
Organism=Homo sapiens, GI4506209, Length=246, Percent_Identity=43.9024390243902, Blast_Score=222, Evalue=1e-57,
Organism=Homo sapiens, GI24497435, Length=255, Percent_Identity=42.3529411764706, Blast_Score=218, Evalue=2e-56,
Organism=Homo sapiens, GI195539395, Length=245, Percent_Identity=44.0816326530612, Blast_Score=207, Evalue=4e-53,
Organism=Homo sapiens, GI21361144, Length=239, Percent_Identity=40.5857740585774, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI24430151, Length=274, Percent_Identity=37.956204379562, Blast_Score=196, Evalue=1e-49,
Organism=Homo sapiens, GI6005942, Length=245, Percent_Identity=44.4897959183673, Blast_Score=195, Evalue=2e-49,
Organism=Homo sapiens, GI45643123, Length=243, Percent_Identity=39.5061728395062, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI89064750, Length=251, Percent_Identity=39.0438247011952, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI45643125, Length=243, Percent_Identity=39.5061728395062, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI5729991, Length=251, Percent_Identity=39.0438247011952, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI24430155, Length=251, Percent_Identity=39.0438247011952, Blast_Score=177, Evalue=5e-44,
Organism=Homo sapiens, GI157671927, Length=225, Percent_Identity=40.4444444444444, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI40806173, Length=137, Percent_Identity=57.6642335766423, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI24497618, Length=266, Percent_Identity=37.218045112782, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI229577436, Length=257, Percent_Identity=37.7431906614786, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI194018488, Length=235, Percent_Identity=39.5744680851064, Blast_Score=156, Evalue=8e-38,
Organism=Homo sapiens, GI14149767, Length=245, Percent_Identity=38.3673469387755, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI62177112, Length=245, Percent_Identity=38.3673469387755, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI4505725, Length=252, Percent_Identity=34.9206349206349, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI5901990, Length=245, Percent_Identity=37.5510204081633, Blast_Score=154, Evalue=5e-37,
Organism=Homo sapiens, GI153792536, Length=239, Percent_Identity=37.2384937238494, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI226371754, Length=258, Percent_Identity=34.1085271317829, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI7019569, Length=242, Percent_Identity=36.7768595041322, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI17865802, Length=240, Percent_Identity=37.5, Blast_Score=137, Evalue=6e-32,
Organism=Homo sapiens, GI31377644, Length=241, Percent_Identity=36.9294605809129, Blast_Score=137, Evalue=6e-32,
Organism=Homo sapiens, GI156564401, Length=277, Percent_Identity=33.2129963898917, Blast_Score=136, Evalue=8e-32,
Organism=Homo sapiens, GI11875211, Length=228, Percent_Identity=39.4736842105263, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI40806170, Length=228, Percent_Identity=39.4736842105263, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI31742536, Length=250, Percent_Identity=34.4, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI112789543, Length=250, Percent_Identity=34.4, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI310125280, Length=225, Percent_Identity=33.7777777777778, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI310125282, Length=225, Percent_Identity=33.7777777777778, Blast_Score=123, Evalue=9e-28,
Organism=Homo sapiens, GI64084766, Length=226, Percent_Identity=26.1061946902655, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI116292174, Length=232, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI1789568, Length=507, Percent_Identity=57.0019723865878, Blast_Score=575, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71994521, Length=463, Percent_Identity=49.0280777537797, Blast_Score=442, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17554264, Length=452, Percent_Identity=47.3451327433628, Blast_Score=398, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI115534323, Length=489, Percent_Identity=43.3537832310838, Blast_Score=361, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI17554786, Length=255, Percent_Identity=42.7450980392157, Blast_Score=223, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17563248, Length=248, Percent_Identity=43.9516129032258, Blast_Score=219, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI25144278, Length=255, Percent_Identity=42.3529411764706, Blast_Score=216, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI25144281, Length=255, Percent_Identity=42.3529411764706, Blast_Score=216, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI71987364, Length=245, Percent_Identity=44.0816326530612, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71987372, Length=245, Percent_Identity=44.0816326530612, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17532375, Length=292, Percent_Identity=36.6438356164384, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17563250, Length=249, Percent_Identity=40.1606425702811, Blast_Score=192, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17508701, Length=239, Percent_Identity=38.4937238493724, Blast_Score=186, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17531535, Length=230, Percent_Identity=43.4782608695652, Blast_Score=185, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17508053, Length=239, Percent_Identity=41.4225941422594, Blast_Score=181, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17505546, Length=251, Percent_Identity=38.6454183266932, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17537217, Length=231, Percent_Identity=39.3939393939394, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17554784, Length=246, Percent_Identity=37.8048780487805, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25153574, Length=229, Percent_Identity=37.5545851528384, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI193206114, Length=237, Percent_Identity=39.2405063291139, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI133931034, Length=237, Percent_Identity=39.2405063291139, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI193206116, Length=237, Percent_Identity=39.2405063291139, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI193209502, Length=228, Percent_Identity=37.280701754386, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=47.2727272727273, Blast_Score=143, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=47.2727272727273, Blast_Score=143, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17562804, Length=233, Percent_Identity=36.480686695279, Blast_Score=138, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI133901662, Length=206, Percent_Identity=37.8640776699029, Blast_Score=134, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI133901658, Length=247, Percent_Identity=34.412955465587, Blast_Score=133, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI25146157, Length=233, Percent_Identity=37.7682403433476, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI86561515, Length=237, Percent_Identity=34.5991561181435, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17560432, Length=233, Percent_Identity=37.3390557939914, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32563584, Length=236, Percent_Identity=36.864406779661, Blast_Score=119, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17508421, Length=236, Percent_Identity=36.864406779661, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17541224, Length=234, Percent_Identity=34.6153846153846, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17541226, Length=234, Percent_Identity=34.6153846153846, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71990294, Length=202, Percent_Identity=30.1980198019802, Blast_Score=70, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320854, Length=517, Percent_Identity=46.42166344294, Blast_Score=443, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6323736, Length=505, Percent_Identity=45.9405940594059, Blast_Score=424, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6325281, Length=541, Percent_Identity=40.1109057301294, Blast_Score=399, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6322704, Length=253, Percent_Identity=43.4782608695652, Blast_Score=223, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6321390, Length=245, Percent_Identity=42.0408163265306, Blast_Score=213, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6320077, Length=227, Percent_Identity=44.0528634361233, Blast_Score=204, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=43.9024390243902, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324691, Length=244, Percent_Identity=41.8032786885246, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6320197, Length=274, Percent_Identity=36.1313868613139, Blast_Score=188, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6324000, Length=232, Percent_Identity=40.5172413793103, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6320602, Length=249, Percent_Identity=38.9558232931727, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6322994, Length=232, Percent_Identity=41.3793103448276, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323429, Length=227, Percent_Identity=40.0881057268723, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6321709, Length=238, Percent_Identity=38.655462184874, Blast_Score=164, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6322651, Length=289, Percent_Identity=33.9100346020761, Blast_Score=161, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6325431, Length=240, Percent_Identity=36.6666666666667, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321465, Length=230, Percent_Identity=37.3913043478261, Blast_Score=134, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6325183, Length=240, Percent_Identity=34.1666666666667, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319554, Length=216, Percent_Identity=35.1851851851852, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320887, Length=262, Percent_Identity=33.206106870229, Blast_Score=114, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6320583, Length=167, Percent_Identity=31.7365269461078, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28574878, Length=502, Percent_Identity=46.2151394422311, Blast_Score=442, Evalue=1e-124,
Organism=Drosophila melanogaster, GI24665814, Length=502, Percent_Identity=46.2151394422311, Blast_Score=442, Evalue=1e-124,
Organism=Drosophila melanogaster, GI24658770, Length=446, Percent_Identity=49.1031390134529, Blast_Score=414, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24639391, Length=460, Percent_Identity=43.9130434782609, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI17137738, Length=246, Percent_Identity=45.1219512195122, Blast_Score=223, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24651451, Length=255, Percent_Identity=41.9607843137255, Blast_Score=216, Evalue=8e-56,
Organism=Drosophila melanogaster, GI19920408, Length=255, Percent_Identity=41.5686274509804, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI45554047, Length=169, Percent_Identity=57.396449704142, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=43.6734693877551, Blast_Score=203, Evalue=4e-52,
Organism=Drosophila melanogaster, GI161076486, Length=270, Percent_Identity=38.1481481481481, Blast_Score=201, Evalue=2e-51,
Organism=Drosophila melanogaster, GI17137560, Length=270, Percent_Identity=38.1481481481481, Blast_Score=201, Evalue=3e-51,
Organism=Drosophila melanogaster, GI161076488, Length=270, Percent_Identity=38.1481481481481, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24649446, Length=274, Percent_Identity=38.3211678832117, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24663015, Length=245, Percent_Identity=42.4489795918367, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI17738151, Length=239, Percent_Identity=38.4937238493724, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI19921202, Length=227, Percent_Identity=41.4096916299559, Blast_Score=182, Evalue=7e-46,
Organism=Drosophila melanogaster, GI24660075, Length=230, Percent_Identity=40, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI281365776, Length=230, Percent_Identity=40, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI45552965, Length=230, Percent_Identity=40, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24652279, Length=236, Percent_Identity=39.4067796610169, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281361487, Length=237, Percent_Identity=38.8185654008439, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI18860063, Length=237, Percent_Identity=38.3966244725738, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI281363136, Length=236, Percent_Identity=39.8305084745763, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI78707192, Length=236, Percent_Identity=39.8305084745763, Blast_Score=170, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24656825, Length=230, Percent_Identity=39.5652173913043, Blast_Score=164, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24656820, Length=230, Percent_Identity=39.5652173913043, Blast_Score=164, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24644145, Length=245, Percent_Identity=37.5510204081633, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI18859657, Length=238, Percent_Identity=39.4957983193277, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21355121, Length=246, Percent_Identity=32.520325203252, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360144, Length=245, Percent_Identity=37.9591836734694, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281360140, Length=245, Percent_Identity=37.9591836734694, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281360136, Length=245, Percent_Identity=37.9591836734694, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24644411, Length=245, Percent_Identity=37.9591836734694, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281360142, Length=245, Percent_Identity=37.9591836734694, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI21357333, Length=245, Percent_Identity=37.9591836734694, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI281360146, Length=245, Percent_Identity=37.9591836734694, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI281360138, Length=245, Percent_Identity=37.9591836734694, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI20129529, Length=300, Percent_Identity=32.6666666666667, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI20129423, Length=261, Percent_Identity=34.8659003831418, Blast_Score=133, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24581396, Length=233, Percent_Identity=35.6223175965665, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28571849, Length=239, Percent_Identity=37.2384937238494, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28571847, Length=239, Percent_Identity=37.2384937238494, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI17864540, Length=208, Percent_Identity=37.5, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573010, Length=272, Percent_Identity=32.7205882352941, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24639486, Length=202, Percent_Identity=33.6633663366337, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH_PARUW (Q6MDI5)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007639.1
- ProteinModelPortal:   Q6MDI5
- STRING:   Q6MDI5
- MEROPS:   M41.001
- GeneID:   2779491
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0640
- NMPDR:   fig|264201.1.peg.640
- eggNOG:   COG0465
- HOGENOM:   HBG724153
- OMA:   HYLELID
- PhylomeDB:   Q6MDI5
- ProtClustDB:   CLSK871624
- BioCyc:   CPRO264201:PC0640-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF01434 Peptidase_M41

EC number: 3.4.24.-

Molecular weight: Translated: 102326; Mature: 102195

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00674 AAA

Important sites: ACT_SITE 687-687

Signals:

None

Transmembrane regions:

HASH(0x403cbee0)-; HASH(0xcebe43c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDNKQDFKKGISNSFVWFLMAAFLFALMVQNFIDTKFAKVSFSYQLEHLVNLQLLQPE
CCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCEEEECCC
DSRKIALNDNLVTFSGKFRDRLTEEGKTRYKYLELLDTNHELKAEQARVKDEIKTLKTKV
CCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FDSASLFLQLSGLSIPKGGYVVVDDMYNTPEEDQSVVIKDLPKSAVESLVSLEKEYEAAR
HCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
QNPTAESLKNLGNLINELLRNLRSPALGIGSETIKQSLKGIDKEVADSGATSLSEQLAAY
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GHALVNLKAIIDELNHEEDHIRLAKLRSVRNYKETLDEYNQINTRLDDNQIQLDKARQSV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SNVIWYFNNQELSTKALEKQDPEVYNQWFSKAKEEWANFSHNRGGIFRAPDQPLNAVLEK
HHEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHH
TFKSEEPSPNYFSYLFTLLPVLLVILVLYMLFARQMKGMGNTAMNFGKSPARLLNKGDNK
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHCCCCCE
ITFKDVAGVDEALEELQEIVEFLKNPQKFTSLGGKIPKGVLCIGPPGTGKTLIAKAVAGE
EEEHHHCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCCC
ADRPFFSISGSDFVEMFVGVGASRIRDLFEQAKKAAPCIIFMDEIDAVGRHRGVGMGGGH
CCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCC
DEREQTLNQLLVEMDGFDTNEGVILMAATNRPDVLDKALLRPGRFDRRVIIGLPDIKGRY
CHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCEEEEECCCCCCCH
DILKVHARRIKMDPSIDLMAIARSTPGSSGADLANILNESALLAARKGRTAVTAQETIEA
HHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
RDKVLYGKERRSLEIDENEKRTTAYHESGHTVVGLIVKSGDPVDKVTIIPRGMSLGATMF
HHHHHCCCCCCCCCCCCCCCHHHHECCCCCEEEEEEEECCCCCCEEEEEECCCCCCCEEE
LPKKNRVSYWKQELHDQLAVLMGGRVAEEIFVGDVSSGAQQDIERATQLARSMVCKWGMS
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
DKLGAVAYDERSEGGGQYGFGDHHEKTYSDETAQAIDSEVRRILDEALAIARKIILDYKE
CCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVELLTLMLIEFETLDSEDIQEIVVKNNWDAVRKRERLKRAADLHKKEAATPPPPPPREV
HHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
DISSSGTIPNTLGLSS
CCCCCCCCCCCCCCCH
>Mature Secondary Structure 
SDDNKQDFKKGISNSFVWFLMAAFLFALMVQNFIDTKFAKVSFSYQLEHLVNLQLLQPE
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCEEEECCC
DSRKIALNDNLVTFSGKFRDRLTEEGKTRYKYLELLDTNHELKAEQARVKDEIKTLKTKV
CCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FDSASLFLQLSGLSIPKGGYVVVDDMYNTPEEDQSVVIKDLPKSAVESLVSLEKEYEAAR
HCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
QNPTAESLKNLGNLINELLRNLRSPALGIGSETIKQSLKGIDKEVADSGATSLSEQLAAY
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GHALVNLKAIIDELNHEEDHIRLAKLRSVRNYKETLDEYNQINTRLDDNQIQLDKARQSV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
SNVIWYFNNQELSTKALEKQDPEVYNQWFSKAKEEWANFSHNRGGIFRAPDQPLNAVLEK
HHEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHH
TFKSEEPSPNYFSYLFTLLPVLLVILVLYMLFARQMKGMGNTAMNFGKSPARLLNKGDNK
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHCCCCCE
ITFKDVAGVDEALEELQEIVEFLKNPQKFTSLGGKIPKGVLCIGPPGTGKTLIAKAVAGE
EEEHHHCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHCCC
ADRPFFSISGSDFVEMFVGVGASRIRDLFEQAKKAAPCIIFMDEIDAVGRHRGVGMGGGH
CCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCC
DEREQTLNQLLVEMDGFDTNEGVILMAATNRPDVLDKALLRPGRFDRRVIIGLPDIKGRY
CHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCEEEEECCCCCCCH
DILKVHARRIKMDPSIDLMAIARSTPGSSGADLANILNESALLAARKGRTAVTAQETIEA
HHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
RDKVLYGKERRSLEIDENEKRTTAYHESGHTVVGLIVKSGDPVDKVTIIPRGMSLGATMF
HHHHHCCCCCCCCCCCCCCCHHHHECCCCCEEEEEEEECCCCCCEEEEEECCCCCCCEEE
LPKKNRVSYWKQELHDQLAVLMGGRVAEEIFVGDVSSGAQQDIERATQLARSMVCKWGMS
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
DKLGAVAYDERSEGGGQYGFGDHHEKTYSDETAQAIDSEVRRILDEALAIARKIILDYKE
CCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVELLTLMLIEFETLDSEDIQEIVVKNNWDAVRKRERLKRAADLHKKEAATPPPPPPREV
HHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
DISSSGTIPNTLGLSS
CCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA