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The map label for this gene is mocA [H]

Identifier: 46446177

GI number: 46446177

Start: 675386

End: 676417

Strand: Direct

Name: mocA [H]

Synonym: pc0543

Alternate gene names: 46446177

Gene position: 675386-676417 (Clockwise)

Preceding gene: 46446176

Following gene: 46446179

Centisome position: 27.97

GC content: 37.6

Gene sequence:

>1032_bases
ATGGAATATAGACAGCTTGGGCGTTCGGGTTTGAAAGTCCCCGCCTTAAGTTTTGGAACTGCAACTTTTGGAGGGACTAA
CGAATTTTTTAAGAAGTGGGGAGATACAGATGTTCAAGAAGCCACTCGTCTTATTAATTTATGTCTAGAGTCCGGGATTA
CCTTATTTGATACAGCCAATGTTTATTCTGCAGGAGCTTCAGAAGAAATTTTAGGTAAAGCACTTAAAGGAAAGCGTGAA
CAAGTTTTAATTTCTACTAAAGCGACCTTTAAAGTTGGCGATAAAGCAAATGATTTAGGATCTTCACGTTATCACATTAT
TGAAGCCTGTGAAGCTAGTTTAAAAAGACTAGGAACAGATCATATTGATATTTATTTTATGCATGGTTTTGATGCTTTAA
CACCACCAGAAGAAACCTTAGGGGCATTAGACAATCTGATTCAAAGTGGGAAAGTTCGTTATATTGGATGTTCAAATTTT
TCTGGTTGGCATTTAATGAAATCACTAGCAACTTCTGAAAAATATGGTTTAGCTCGCTATGTTGTCTATCAAGGGTATTA
TTCTTTGATAGGAAGAGATTACGAAGAAGAATTGATGCCTCTTGGAATAGATCAAGGAGTAGGATTGATGGCTTGGAGCC
CGCTTGGATGGGGACGGTTAACTGGGAAAATACGAAGAGGGAAAAAACCTGCTGAAGGACGTATAAATGAGGGTGGATCT
GTTGGAGGTCCTCCAGTAGATGATGAATATTTATACAATGTCATTGATGCGATTGATCAAATAGCTAAAGAAACAGGAAA
AACAATTCCACAAATTGCCTTAAATTGGATTTTACAAAGGCCCACTGTTGTTAATGTTGTTGTTGGAGCTCGTAATGAGG
AACAGTTAAAACAAAATCTCGGTGTACTCAATTGGAGTCTAACAAAAGAACAAATTGCCAAATTAGACGCGGCGAGTGAA
AAGCAACCTGTTTACCCTTACTGGCATCAAAGAGATTTTAAAGAAAGAAATCCTCGACCAATTCCTTCATAA

Upstream 100 bases:

>100_bases
TTGTTTAATACCTCTAAATATATTATGCATAAAATTTTTGATTGAAAGGTCCCATTTTGAGCTATCAGAGTATCAACTGA
ATTAACGATAGGAAGGTTTT

Downstream 100 bases:

>100_bases
TTTTTAATTTTTAGAGTTAATAGTGAACTTAACTTTTTATGCCTACCCACCCCTCGAGAAAAAATTTCGAGGGATGATTA
GTAATTTACAAGAGTCATTT

Product: MocA family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MEYRQLGRSGLKVPALSFGTATFGGTNEFFKKWGDTDVQEATRLINLCLESGITLFDTANVYSAGASEEILGKALKGKRE
QVLISTKATFKVGDKANDLGSSRYHIIEACEASLKRLGTDHIDIYFMHGFDALTPPEETLGALDNLIQSGKVRYIGCSNF
SGWHLMKSLATSEKYGLARYVVYQGYYSLIGRDYEEELMPLGIDQGVGLMAWSPLGWGRLTGKIRRGKKPAEGRINEGGS
VGGPPVDDEYLYNVIDAIDQIAKETGKTIPQIALNWILQRPTVVNVVVGARNEEQLKQNLGVLNWSLTKEQIAKLDAASE
KQPVYPYWHQRDFKERNPRPIPS

Sequences:

>Translated_343_residues
MEYRQLGRSGLKVPALSFGTATFGGTNEFFKKWGDTDVQEATRLINLCLESGITLFDTANVYSAGASEEILGKALKGKRE
QVLISTKATFKVGDKANDLGSSRYHIIEACEASLKRLGTDHIDIYFMHGFDALTPPEETLGALDNLIQSGKVRYIGCSNF
SGWHLMKSLATSEKYGLARYVVYQGYYSLIGRDYEEELMPLGIDQGVGLMAWSPLGWGRLTGKIRRGKKPAEGRINEGGS
VGGPPVDDEYLYNVIDAIDQIAKETGKTIPQIALNWILQRPTVVNVVVGARNEEQLKQNLGVLNWSLTKEQIAKLDAASE
KQPVYPYWHQRDFKERNPRPIPS
>Mature_343_residues
MEYRQLGRSGLKVPALSFGTATFGGTNEFFKKWGDTDVQEATRLINLCLESGITLFDTANVYSAGASEEILGKALKGKRE
QVLISTKATFKVGDKANDLGSSRYHIIEACEASLKRLGTDHIDIYFMHGFDALTPPEETLGALDNLIQSGKVRYIGCSNF
SGWHLMKSLATSEKYGLARYVVYQGYYSLIGRDYEEELMPLGIDQGVGLMAWSPLGWGRLTGKIRRGKKPAEGRINEGGS
VGGPPVDDEYLYNVIDAIDQIAKETGKTIPQIALNWILQRPTVVNVVVGARNEEQLKQNLGVLNWSLTKEQIAKLDAASE
KQPVYPYWHQRDFKERNPRPIPS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=349, Percent_Identity=33.2378223495702, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI4504825, Length=347, Percent_Identity=33.1412103746398, Blast_Score=164, Evalue=9e-41,
Organism=Homo sapiens, GI27436964, Length=343, Percent_Identity=32.6530612244898, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI27436962, Length=343, Percent_Identity=32.6530612244898, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI27436966, Length=343, Percent_Identity=32.3615160349854, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI27436971, Length=335, Percent_Identity=32.5373134328358, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI223718702, Length=284, Percent_Identity=30.9859154929577, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI41152114, Length=272, Percent_Identity=32.7205882352941, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI41327764, Length=272, Percent_Identity=33.0882352941176, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI223718708, Length=167, Percent_Identity=33.5329341317365, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081735, Length=327, Percent_Identity=37.9204892966361, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=32.6219512195122, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1788070, Length=326, Percent_Identity=34.6625766871166, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789199, Length=360, Percent_Identity=31.9444444444444, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788081, Length=272, Percent_Identity=30.8823529411765, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI48994888, Length=283, Percent_Identity=27.5618374558304, Blast_Score=85, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI212645785, Length=313, Percent_Identity=27.4760383386581, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=343, Percent_Identity=30.6122448979592, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=31.1526479750779, Blast_Score=142, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=30.4054054054054, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319951, Length=321, Percent_Identity=28.0373831775701, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322615, Length=249, Percent_Identity=29.718875502008, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24640980, Length=350, Percent_Identity=28.8571428571429, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45549126, Length=350, Percent_Identity=28.8571428571429, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24646155, Length=308, Percent_Identity=28.2467532467532, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646159, Length=340, Percent_Identity=26.7647058823529, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644950, Length=361, Percent_Identity=24.9307479224377, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38097; Mature: 38097

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRQLGRSGLKVPALSFGTATFGGTNEFFKKWGDTDVQEATRLINLCLESGITLFDTAN
CCHHHHCCCCCCCCCEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCC
VYSAGASEEILGKALKGKREQVLISTKATFKVGDKANDLGSSRYHIIEACEASLKRLGTD
HHCCCCCHHHHHHHHCCCCCEEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
HIDIYFMHGFDALTPPEETLGALDNLIQSGKVRYIGCSNFSGWHLMKSLATSEKYGLARY
CEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VVYQGYYSLIGRDYEEELMPLGIDQGVGLMAWSPLGWGRLTGKIRRGKKPAEGRINEGGS
HHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCC
VGGPPVDDEYLYNVIDAIDQIAKETGKTIPQIALNWILQRPTVVNVVVGARNEEQLKQNL
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHC
GVLNWSLTKEQIAKLDAASEKQPVYPYWHQRDFKERNPRPIPS
CCEEECCCHHHHHHHCCCCCCCCCCCCHHCCCHHHCCCCCCCC
>Mature Secondary Structure
MEYRQLGRSGLKVPALSFGTATFGGTNEFFKKWGDTDVQEATRLINLCLESGITLFDTAN
CCHHHHCCCCCCCCCEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCC
VYSAGASEEILGKALKGKREQVLISTKATFKVGDKANDLGSSRYHIIEACEASLKRLGTD
HHCCCCCHHHHHHHHCCCCCEEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
HIDIYFMHGFDALTPPEETLGALDNLIQSGKVRYIGCSNFSGWHLMKSLATSEKYGLARY
CEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VVYQGYYSLIGRDYEEELMPLGIDQGVGLMAWSPLGWGRLTGKIRRGKKPAEGRINEGGS
HHHHHHHHHHCCCHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCC
VGGPPVDDEYLYNVIDAIDQIAKETGKTIPQIALNWILQRPTVVNVVVGARNEEQLKQNL
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHC
GVLNWSLTKEQIAKLDAASEKQPVYPYWHQRDFKERNPRPIPS
CCEEECCCHHHHHHHCCCCCCCCCCCCHHCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]