Click here to switch to the map view.

The map label for this gene is mltF [H]

Identifier: 45659293

GI number: 45659293

Start: 4252579

End: 4253427

Strand: Reverse

Name: mltF [H]

Synonym: LIC13478

Alternate gene names: 45659293

Gene position: 4253427-4252579 (Counterclockwise)

Preceding gene: 45659294

Following gene: 45659292

Centisome position: 99.44

GC content: 33.8

Gene sequence:

>849_bases
ATGTTCGAGAAGAATTTTTTTTATCTACTTTTGATTTTTGTTTTTTCGAGCGGTTTATTTTCTCAGTCGGAATACTCCGG
CTCCAGACTGGAAAAGATTCTTTCTAAAAAAGAACTTATAGTAGGAGTTAATAAACAATACGAACCGTTTTATATCGAAA
ATCCAAAAGATGGTTATCCAGGTATCGATGCGGAGTTAGCAAAACTCTATGCGGATTATCTCGGTGTTTCTTTAAAGCTA
ATTCCGATGAAAACGTTTAGGCAATTTTCGGAAGATATTCGAGTAGGCAAGATTGATCTTGCTTTGGCCGGGATTTCCAC
GGATTTAAATCGAGGTAAACAAGTTACTTTTTCGGATCCTTATCTTGTTACAACTCCGGCGGGACTCGTGAGTAAAAAAA
TTCTTCCTCCAGAGCCAGAAGGAAATATTGTTACTTCCAGAAGATTTATTAGTTTAAATGATCTTTTTACTCTAAGTGGA
TTGGTGAGTTTTTCTGTAAGATCTAATACTACGAATCACATTTATCTTCAAAAGAAATTTTCTAAACTTCCAATTTACAG
TTATCTTTCGGATTCGATTGCGGTTGATAATCTTATCAGTAACAATGTAACTTGTTTTGTTGCGGATAGTTTTTTTATTC
TTACTTTACTTCAAAAAAATCCGTCTTTGAGAGCAAATTATCTTCCTCTTTTAGGAACTGTTCAAGAGGAAAATATCAGC
GCTGCTCTTCCACAGAACGATTTGATTTTTGCGGATAATTTAAATTTCTTTATTAAAGAATTGAAACGAACCGGTGTTTT
AGACGATTTAAGAAACCGATATTTTAATCAGAACAACTGGGTAAAATGA

Upstream 100 bases:

>100_bases
AAATAGAAGAACCGAATTTCAGATTATCAGTCGTTAGAAATTTATGATTCTAATTTAAAATGCTCTGGAAAAAAACAAGG
ATCGACCTATTCTTTGTTTC

Downstream 100 bases:

>100_bases
TCCGTGTCTGACAACCTTTTAAAAAAGGCTTATCTATTCTATTTCCTTGTGTTGATTTTATTTCCATCTTTGCTTTTTTC
TCAAGAAATTGAGGAAAAAA

Product: cystine-binding periplasmic protein precursor

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MFEKNFFYLLLIFVFSSGLFSQSEYSGSRLEKILSKKELIVGVNKQYEPFYIENPKDGYPGIDAELAKLYADYLGVSLKL
IPMKTFRQFSEDIRVGKIDLALAGISTDLNRGKQVTFSDPYLVTTPAGLVSKKILPPEPEGNIVTSRRFISLNDLFTLSG
LVSFSVRSNTTNHIYLQKKFSKLPIYSYLSDSIAVDNLISNNVTCFVADSFFILTLLQKNPSLRANYLPLLGTVQEENIS
AALPQNDLIFADNLNFFIKELKRTGVLDDLRNRYFNQNNWVK

Sequences:

>Translated_282_residues
MFEKNFFYLLLIFVFSSGLFSQSEYSGSRLEKILSKKELIVGVNKQYEPFYIENPKDGYPGIDAELAKLYADYLGVSLKL
IPMKTFRQFSEDIRVGKIDLALAGISTDLNRGKQVTFSDPYLVTTPAGLVSKKILPPEPEGNIVTSRRFISLNDLFTLSG
LVSFSVRSNTTNHIYLQKKFSKLPIYSYLSDSIAVDNLISNNVTCFVADSFFILTLLQKNPSLRANYLPLLGTVQEENIS
AALPQNDLIFADNLNFFIKELKRTGVLDDLRNRYFNQNNWVK
>Mature_282_residues
MFEKNFFYLLLIFVFSSGLFSQSEYSGSRLEKILSKKELIVGVNKQYEPFYIENPKDGYPGIDAELAKLYADYLGVSLKL
IPMKTFRQFSEDIRVGKIDLALAGISTDLNRGKQVTFSDPYLVTTPAGLVSKKILPPEPEGNIVTSRRFISLNDLFTLSG
LVSFSVRSNTTNHIYLQKKFSKLPIYSYLSDSIAVDNLISNNVTCFVADSFFILTLLQKNPSLRANYLPLLGTVQEENIS
AALPQNDLIFADNLNFFIKELKRTGVLDDLRNRYFNQNNWVK

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

None

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 32009; Mature: 32009

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKNFFYLLLIFVFSSGLFSQSEYSGSRLEKILSKKELIVGVNKQYEPFYIENPKDGYP
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCC
GIDAELAKLYADYLGVSLKLIPMKTFRQFSEDIRVGKIDLALAGISTDLNRGKQVTFSDP
CCCHHHHHHHHHHHCCEEEEEEHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCC
YLVTTPAGLVSKKILPPEPEGNIVTSRRFISLNDLFTLSGLVSFSVRSNTTNHIYLQKKF
EEEECCHHHHHCCCCCCCCCCCEEECEEEEEHHHHHHHHHHEEEEEECCCCCEEEEEECC
SKLPIYSYLSDSIAVDNLISNNVTCFVADSFFILTLLQKNPSLRANYLPLLGTVQEENIS
CCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEHHHHCCCCCCCCCCCEEEEEECCCCE
AALPQNDLIFADNLNFFIKELKRTGVLDDLRNRYFNQNNWVK
EECCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFEKNFFYLLLIFVFSSGLFSQSEYSGSRLEKILSKKELIVGVNKQYEPFYIENPKDGYP
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCC
GIDAELAKLYADYLGVSLKLIPMKTFRQFSEDIRVGKIDLALAGISTDLNRGKQVTFSDP
CCCHHHHHHHHHHHCCEEEEEEHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEECCC
YLVTTPAGLVSKKILPPEPEGNIVTSRRFISLNDLFTLSGLVSFSVRSNTTNHIYLQKKF
EEEECCHHHHHCCCCCCCCCCCEEECEEEEEHHHHHHHHHHEEEEEECCCCCEEEEEECC
SKLPIYSYLSDSIAVDNLISNNVTCFVADSFFILTLLQKNPSLRANYLPLLGTVQEENIS
CCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEHHHHCCCCCCCCCCCEEEEEECCCCE
AALPQNDLIFADNLNFFIKELKRTGVLDDLRNRYFNQNNWVK
EECCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA