Click here to switch to the map view.

The map label for this gene is dmcA

Identifier: 45659211

GI number: 45659211

Start: 4159953

End: 4161545

Strand: Reverse

Name: dmcA

Synonym: LIC13394

Alternate gene names: 45659211

Gene position: 4161545-4159953 (Counterclockwise)

Preceding gene: 45659216

Following gene: 45659210

Centisome position: 97.3

GC content: 35.84

Gene sequence:

>1593_bases
ATGCCCTTAAAAAAAGAAACAAAAAGAAAAACCGACGAGGAAATCATCGCCTCGGGTCCCACCTATATCAATTGGATTCG
GTTTGGGTTGATTTTGCTTTTTTATACTTCAATTTTAATTAACTGGAAACGGACCAACTCAATTCAAAATATTTTATATT
TGAGCGGCACGACTGCTATGTTTCTTAATTTTATCTATAGCTTTTATAAAATTCGAAAGACAGGTAGTATATCTCATACT
CTCAGTAAAGTATTTCTACTTGTGGATGTTTTAGTCCAGCTTGTGGTTATGATGGGTGCCACTATGGATCATCCCGATTT
TACCACTGGTGTGGTAAAAAGTCCTATCTTATACGGGATCAGTTATATGTACATAGTTTCCTCCGGACTTTTGTTGGTTC
CTAATTTTGTGCTTTGGATCGGATTTTTGTCTGGGGGAGCACAGGCTTTGGCGATTTTTACTGCGACACGATATGGCTTG
ATTTTAACGGAACAAAAGAAACTTGCCAATTCGTTGGGGTATGCTTCTGTTTCGGAACAAATTACAAAAATCTTATTCGT
ATTTGCCTGTGCAGTAATTGTTAGAATCCTTGTAAAACTGTTTATGCGATTGAGAGAAAATTCTAGGTATAGACAAGAAG
CATTAGAAGAATCTCATAAACTAATTGCTCAAAGAAGTTCTAAGATGAAAGAATCCGCGCAATATCTGAAAGATTCCTCT
AAAAATTTAAAGAGTTTTATGGATGATCTTTCTGTTTTAGTTTCTACACAAGCTTCTTCTTTTGAAGAAATCAGCTCCAC
AGTGGAACAATTTCAATCTCAAACTGAGAATTCTTCGTATAACGTAAAAAATCAGTTTAGAAATATTGAAAGTTTAATTC
TTCATAGTAATAATTTAAAATCGATTATAGAAAAAATTTCTAACTTCAACCAAACCTTGGACCAAAGTATGGATAAAGTT
CGTAAGTCTGGGACAATGGTCACTAAGTTTGTGGAAGAGTTGTCAGGTTCTCTTTCTTCTTTGGGAGATTCTTTTAGAAG
TGTGGGAGAAGTGAATCGAATTATGTCCGAGGTTGCGGATAGGACTAATTTACTTTCTTTGAATGCGTCTATTGAAGCGG
CTAGAGCCGGAGAAGCTGGTAGAGGTTTTGCGGTTGTTGCACAAGAAGTTTCTAAACTTGCGGAAAGTAGTGCTGGAAAT
GCGGATTTAATTTCAAAAATTATTCGGGACTCTTCTAACCATGTGCAAATGGGTCGGGAGTCTGCTGAAACTACTGCAGG
TCACGTGAAAGAACAAGATACTCTAATTCAAGATTTGTTTGTTCGATTTGATGAGTTTTCAAATTTATTCTACGAACAAA
GGAAAATTAATTCCGAATTTTTTTCTACCTTAGATCGTTTGCGTTCTTTATCTTCGGAGATCGAACTTGCTTCCTCTGAA
CAAAAAATGGGATTACAAGGAATTGTAGAAGCGATTTCCTTACTTCAAAATTCTATGGAATCTTTGGTTACAAAAAGTGA
AAACTTAAGCGTGGTCGTCAGAGAATTAGAAACACAATCAGATACGCTTATCCTTGCAGAAACAAACACCTAA

Upstream 100 bases:

>100_bases
TTGTTTCAGAAATTTTGATAAAATGAATATTTAATGTACTTCTTGCTCTAGGTTTTTAGAAAAACCATTGATTTTTCAAA
GTACGTAACACTATTAGTCT

Downstream 100 bases:

>100_bases
CGGTGAAAAGGTGTTATATATTTTTTAAAATAGCTTCTGTAAAAAATTTTAATTCTATGATGGTTGTATAGTAGTGATTT
TATGGAGAATTTGATTTTGT

Product: methyl-accepting chemotaxis transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MPLKKETKRKTDEEIIASGPTYINWIRFGLILLFYTSILINWKRTNSIQNILYLSGTTAMFLNFIYSFYKIRKTGSISHT
LSKVFLLVDVLVQLVVMMGATMDHPDFTTGVVKSPILYGISYMYIVSSGLLLVPNFVLWIGFLSGGAQALAIFTATRYGL
ILTEQKKLANSLGYASVSEQITKILFVFACAVIVRILVKLFMRLRENSRYRQEALEESHKLIAQRSSKMKESAQYLKDSS
KNLKSFMDDLSVLVSTQASSFEEISSTVEQFQSQTENSSYNVKNQFRNIESLILHSNNLKSIIEKISNFNQTLDQSMDKV
RKSGTMVTKFVEELSGSLSSLGDSFRSVGEVNRIMSEVADRTNLLSLNASIEAARAGEAGRGFAVVAQEVSKLAESSAGN
ADLISKIIRDSSNHVQMGRESAETTAGHVKEQDTLIQDLFVRFDEFSNLFYEQRKINSEFFSTLDRLRSLSSEIELASSE
QKMGLQGIVEAISLLQNSMESLVTKSENLSVVVRELETQSDTLILAETNT

Sequences:

>Translated_530_residues
MPLKKETKRKTDEEIIASGPTYINWIRFGLILLFYTSILINWKRTNSIQNILYLSGTTAMFLNFIYSFYKIRKTGSISHT
LSKVFLLVDVLVQLVVMMGATMDHPDFTTGVVKSPILYGISYMYIVSSGLLLVPNFVLWIGFLSGGAQALAIFTATRYGL
ILTEQKKLANSLGYASVSEQITKILFVFACAVIVRILVKLFMRLRENSRYRQEALEESHKLIAQRSSKMKESAQYLKDSS
KNLKSFMDDLSVLVSTQASSFEEISSTVEQFQSQTENSSYNVKNQFRNIESLILHSNNLKSIIEKISNFNQTLDQSMDKV
RKSGTMVTKFVEELSGSLSSLGDSFRSVGEVNRIMSEVADRTNLLSLNASIEAARAGEAGRGFAVVAQEVSKLAESSAGN
ADLISKIIRDSSNHVQMGRESAETTAGHVKEQDTLIQDLFVRFDEFSNLFYEQRKINSEFFSTLDRLRSLSSEIELASSE
QKMGLQGIVEAISLLQNSMESLVTKSENLSVVVRELETQSDTLILAETNT
>Mature_529_residues
PLKKETKRKTDEEIIASGPTYINWIRFGLILLFYTSILINWKRTNSIQNILYLSGTTAMFLNFIYSFYKIRKTGSISHTL
SKVFLLVDVLVQLVVMMGATMDHPDFTTGVVKSPILYGISYMYIVSSGLLLVPNFVLWIGFLSGGAQALAIFTATRYGLI
LTEQKKLANSLGYASVSEQITKILFVFACAVIVRILVKLFMRLRENSRYRQEALEESHKLIAQRSSKMKESAQYLKDSSK
NLKSFMDDLSVLVSTQASSFEEISSTVEQFQSQTENSSYNVKNQFRNIESLILHSNNLKSIIEKISNFNQTLDQSMDKVR
KSGTMVTKFVEELSGSLSSLGDSFRSVGEVNRIMSEVADRTNLLSLNASIEAARAGEAGRGFAVVAQEVSKLAESSAGNA
DLISKIIRDSSNHVQMGRESAETTAGHVKEQDTLIQDLFVRFDEFSNLFYEQRKINSEFFSTLDRLRSLSSEIELASSEQ
KMGLQGIVEAISLLQNSMESLVTKSENLSVVVRELETQSDTLILAETNT

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=222, Percent_Identity=28.3783783783784, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788195, Length=217, Percent_Identity=27.6497695852535, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789453, Length=226, Percent_Identity=27.4336283185841, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI2367378, Length=215, Percent_Identity=27.906976744186, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787690, Length=295, Percent_Identity=25.4237288135593, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59327; Mature: 59196

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKKETKRKTDEEIIASGPTYINWIRFGLILLFYTSILINWKRTNSIQNILYLSGTTAM
CCCCCHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCHHHH
FLNFIYSFYKIRKTGSISHTLSKVFLLVDVLVQLVVMMGATMDHPDFTTGVVKSPILYGI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
SYMYIVSSGLLLVPNFVLWIGFLSGGAQALAIFTATRYGLILTEQKKLANSLGYASVSEQ
HHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEHHHHHHHHCCHHHHHHH
ITKILFVFACAVIVRILVKLFMRLRENSRYRQEALEESHKLIAQRSSKMKESAQYLKDSS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNLKSFMDDLSVLVSTQASSFEEISSTVEQFQSQTENSSYNVKNQFRNIESLILHSNNLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHH
SIIEKISNFNQTLDQSMDKVRKSGTMVTKFVEELSGSLSSLGDSFRSVGEVNRIMSEVAD
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTNLLSLNASIEAARAGEAGRGFAVVAQEVSKLAESSAGNADLISKIIRDSSNHVQMGRE
HHCEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHCHH
SAETTAGHVKEQDTLIQDLFVRFDEFSNLFYEQRKINSEFFSTLDRLRSLSSEIELASSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QKMGLQGIVEAISLLQNSMESLVTKSENLSVVVRELETQSDTLILAETNT
HHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCC
>Mature Secondary Structure 
PLKKETKRKTDEEIIASGPTYINWIRFGLILLFYTSILINWKRTNSIQNILYLSGTTAM
CCCCHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCHHHH
FLNFIYSFYKIRKTGSISHTLSKVFLLVDVLVQLVVMMGATMDHPDFTTGVVKSPILYGI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
SYMYIVSSGLLLVPNFVLWIGFLSGGAQALAIFTATRYGLILTEQKKLANSLGYASVSEQ
HHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEHHHHHHHHCCHHHHHHH
ITKILFVFACAVIVRILVKLFMRLRENSRYRQEALEESHKLIAQRSSKMKESAQYLKDSS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNLKSFMDDLSVLVSTQASSFEEISSTVEQFQSQTENSSYNVKNQFRNIESLILHSNNLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHH
SIIEKISNFNQTLDQSMDKVRKSGTMVTKFVEELSGSLSSLGDSFRSVGEVNRIMSEVAD
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTNLLSLNASIEAARAGEAGRGFAVVAQEVSKLAESSAGNADLISKIIRDSSNHVQMGRE
HHCEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHCHH
SAETTAGHVKEQDTLIQDLFVRFDEFSNLFYEQRKINSEFFSTLDRLRSLSSEIELASSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QKMGLQGIVEAISLLQNSMESLVTKSENLSVVVRELETQSDTLILAETNT
HHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]