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The map label for this gene is katE

Identifier: 45657884

GI number: 45657884

Start: 2452348

End: 2453793

Strand: Reverse

Name: katE

Synonym: LIC12032

Alternate gene names: 45657884

Gene position: 2453793-2452348 (Counterclockwise)

Preceding gene: 45657885

Following gene: 45657883

Centisome position: 57.37

GC content: 38.93

Gene sequence:

>1446_bases
ATGAGTAGAAAAACCCTTACTACAGCTGGAGGTCATCCGGTTTCACAAAATCAACATTCTTTAACCGCCGGACCTCGAGG
GCCGGTTTTAATTCAGGATACACATCTGATCGAAAAACTGGCTCACTTCAATCGAGAAAGAATTCCAGAGAGAGTAGTTC
ATGCAAAAGGTGCTGGGGCTTATGGAACTCTGACCATTACTCAAGATCTTACAAAATATTCTAGAGCTTCTATCTTTTCC
AAAAAGGGAAAACAAACTTCTCTTTTTCTACGTTTTTCTACAGTGGCAGGGGAAAAGGGTTCTGCGGATACGGAAAGAGA
TCCGAGAGGTTTTGCGGTTAAATTTTATACGGACGAAGGAATTTGGGATCTTGTAGGAAACAATACTCCTGTATTTTTTG
CTAGAGATCCTTTGAAGTTTCCTGATTTTATACATTCACAAAAAAGAGATCCTGTCACCGGTTATAAAAACCCAATTCGT
ATGTGGGACTATTGGGCTGGGTCTCCCGAGGCATTTCATCAAATCACCATTCTTTTTGGAGATAGAGGAATCCCGGACGG
CTATCGTTTTATGAACGGTTATGGAAGTCATACTTTTGGACTTTGGAATTCTAAAGGAGAACGTTTTTGGACTAAGTTTC
ACTTTAAATCTATGCAAGGAATTAGGAATCTAAGTATGGAAAAAGCATCTGCGTTAGCCGGAACTGATCCAGATTACGCG
ACTAGGGATTTATTTGAGGCGATTGAAAGAAAGGAATTTCCAAAATGGAAGTTTTGTGTTCAGATCATGCCTGAAAAAGA
AGCTACAAAATATAAATTCAATCCATTTGATCTTACCAAGGTTTGGTCTCATAAAGATTATCCTTTGATAGAAGTAGGGG
TTTTGGAATTGAATTCTAATCCTAAAAATTACTTTGAAGAAGTAGAGCAGGCCGCATTTTCCCCTTCTAATATGCCTCCT
GGAATTGGTGCTTCTCCAGATAAAATGTTACAAGGAAGATTATTCGCATATCCGGATGCTCATAGGTATCGTTTGGGGAT
TCAATACCAGCAACTTCCTGTAAATAGACCTAAAAATTCTGTAAACGTTTATCATAGAGATGGTCGTACTCGATTTCAGT
GTGACGGAAATTATGATAATTATGAGCCAAACGGTTTTGAAGGACCTGTGCAGGATTCTTCTTATGCAGAACCTCCTTTG
AGTATTTCTGGAGATATGGATCGTTATAATTCTCATATAGGAAATGACGATTATTCTCAAGCGGGAGATTTATATAGATT
GATGAGTGTTGAGGAAAGGGAAAGATTGACTTCTGCGATCGCTTCTACGATGCATAATCTTCCTAAACCTTTACTAGAAG
CCAATCTAAAACATTTCCATCTTTGTGATCCGGAGTATGGAGAGCAATTGGCTGCAAAAGTAGGTCTTGCTCTGAGTCGA
GTTTAA

Upstream 100 bases:

>100_bases
ATCTTTTGAGCGGATCTAAATCTTCTCGATTGAAAAGGTTCTTAACTTTTTTCAAATCTTGGATCTTATATATCGTTCAA
TTTACAAAAGGAGAAAAATA

Downstream 100 bases:

>100_bases
AAAAGTGAAAGATAAAATTCACGAATCATTTTTTTAAATACAAATTGAATAAGTTTTACCTATTTAAAAGAGGGTTTTTG
GAATAGTTAGTTTTTTATTT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSRKTLTTAGGHPVSQNQHSLTAGPRGPVLIQDTHLIEKLAHFNRERIPERVVHAKGAGAYGTLTITQDLTKYSRASIFS
KKGKQTSLFLRFSTVAGEKGSADTERDPRGFAVKFYTDEGIWDLVGNNTPVFFARDPLKFPDFIHSQKRDPVTGYKNPIR
MWDYWAGSPEAFHQITILFGDRGIPDGYRFMNGYGSHTFGLWNSKGERFWTKFHFKSMQGIRNLSMEKASALAGTDPDYA
TRDLFEAIERKEFPKWKFCVQIMPEKEATKYKFNPFDLTKVWSHKDYPLIEVGVLELNSNPKNYFEEVEQAAFSPSNMPP
GIGASPDKMLQGRLFAYPDAHRYRLGIQYQQLPVNRPKNSVNVYHRDGRTRFQCDGNYDNYEPNGFEGPVQDSSYAEPPL
SISGDMDRYNSHIGNDDYSQAGDLYRLMSVEERERLTSAIASTMHNLPKPLLEANLKHFHLCDPEYGEQLAAKVGLALSR
V

Sequences:

>Translated_481_residues
MSRKTLTTAGGHPVSQNQHSLTAGPRGPVLIQDTHLIEKLAHFNRERIPERVVHAKGAGAYGTLTITQDLTKYSRASIFS
KKGKQTSLFLRFSTVAGEKGSADTERDPRGFAVKFYTDEGIWDLVGNNTPVFFARDPLKFPDFIHSQKRDPVTGYKNPIR
MWDYWAGSPEAFHQITILFGDRGIPDGYRFMNGYGSHTFGLWNSKGERFWTKFHFKSMQGIRNLSMEKASALAGTDPDYA
TRDLFEAIERKEFPKWKFCVQIMPEKEATKYKFNPFDLTKVWSHKDYPLIEVGVLELNSNPKNYFEEVEQAAFSPSNMPP
GIGASPDKMLQGRLFAYPDAHRYRLGIQYQQLPVNRPKNSVNVYHRDGRTRFQCDGNYDNYEPNGFEGPVQDSSYAEPPL
SISGDMDRYNSHIGNDDYSQAGDLYRLMSVEERERLTSAIASTMHNLPKPLLEANLKHFHLCDPEYGEQLAAKVGLALSR
V
>Mature_480_residues
SRKTLTTAGGHPVSQNQHSLTAGPRGPVLIQDTHLIEKLAHFNRERIPERVVHAKGAGAYGTLTITQDLTKYSRASIFSK
KGKQTSLFLRFSTVAGEKGSADTERDPRGFAVKFYTDEGIWDLVGNNTPVFFARDPLKFPDFIHSQKRDPVTGYKNPIRM
WDYWAGSPEAFHQITILFGDRGIPDGYRFMNGYGSHTFGLWNSKGERFWTKFHFKSMQGIRNLSMEKASALAGTDPDYAT
RDLFEAIERKEFPKWKFCVQIMPEKEATKYKFNPFDLTKVWSHKDYPLIEVGVLELNSNPKNYFEEVEQAAFSPSNMPPG
IGASPDKMLQGRLFAYPDAHRYRLGIQYQQLPVNRPKNSVNVYHRDGRTRFQCDGNYDNYEPNGFEGPVQDSSYAEPPLS
ISGDMDRYNSHIGNDDYSQAGDLYRLMSVEERERLTSAIASTMHNLPKPLLEANLKHFHLCDPEYGEQLAAKVGLALSRV

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=471, Percent_Identity=55.2016985138004, Blast_Score=531, Evalue=1e-151,
Organism=Escherichia coli, GI48994891, Length=387, Percent_Identity=45.2196382428941, Blast_Score=343, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI71998444, Length=474, Percent_Identity=51.2658227848101, Blast_Score=505, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI25147792, Length=470, Percent_Identity=51.9148936170213, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI25151141, Length=468, Percent_Identity=52.1367521367521, Blast_Score=502, Evalue=1e-142,
Organism=Saccharomyces cerevisiae, GI6320462, Length=456, Percent_Identity=44.7368421052632, Blast_Score=380, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6321525, Length=437, Percent_Identity=42.3340961098398, Blast_Score=344, Evalue=2e-95,
Organism=Drosophila melanogaster, GI17981717, Length=487, Percent_Identity=51.5400410677618, Blast_Score=502, Evalue=1e-142,
Organism=Drosophila melanogaster, GI19920968, Length=481, Percent_Identity=45.7380457380457, Blast_Score=445, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54677; Mature: 54546

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKTLTTAGGHPVSQNQHSLTAGPRGPVLIQDTHLIEKLAHFNRERIPERVVHAKGAGA
CCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHCCCCCC
YGTLTITQDLTKYSRASIFSKKGKQTSLFLRFSTVAGEKGSADTERDPRGFAVKFYTDEG
EEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCC
IWDLVGNNTPVFFARDPLKFPDFIHSQKRDPVTGYKNPIRMWDYWAGSPEAFHQITILFG
EEECCCCCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHEEEEEEEEC
DRGIPDGYRFMNGYGSHTFGLWNSKGERFWTKFHFKSMQGIRNLSMEKASALAGTDPDYA
CCCCCCHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TRDLFEAIERKEFPKWKFCVQIMPEKEATKYKFNPFDLTKVWSHKDYPLIEVGVLELNSN
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCEECCCCCHHHHHCCCCCCEEEEEEEEECCC
PKNYFEEVEQAAFSPSNMPPGIGASPDKMLQGRLFAYPDAHRYRLGIQYQQLPVNRPKNS
CHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCEEEECCCCCEEEECCEEEECCCCCCCCC
VNVYHRDGRTRFQCDGNYDNYEPNGFEGPVQDSSYAEPPLSISGDMDRYNSHIGNDDYSQ
CEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHH
AGDLYRLMSVEERERLTSAIASTMHNLPKPLLEANLKHFHLCDPEYGEQLAAKVGLALSR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHC
V
C
>Mature Secondary Structure 
SRKTLTTAGGHPVSQNQHSLTAGPRGPVLIQDTHLIEKLAHFNRERIPERVVHAKGAGA
CCCEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHCCCCCC
YGTLTITQDLTKYSRASIFSKKGKQTSLFLRFSTVAGEKGSADTERDPRGFAVKFYTDEG
EEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCC
IWDLVGNNTPVFFARDPLKFPDFIHSQKRDPVTGYKNPIRMWDYWAGSPEAFHQITILFG
EEECCCCCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHEEEEEEEEC
DRGIPDGYRFMNGYGSHTFGLWNSKGERFWTKFHFKSMQGIRNLSMEKASALAGTDPDYA
CCCCCCHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TRDLFEAIERKEFPKWKFCVQIMPEKEATKYKFNPFDLTKVWSHKDYPLIEVGVLELNSN
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCEECCCCCHHHHHCCCCCCEEEEEEEEECCC
PKNYFEEVEQAAFSPSNMPPGIGASPDKMLQGRLFAYPDAHRYRLGIQYQQLPVNRPKNS
CHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCEEEECCCCCEEEECCEEEECCCCCCCCC
VNVYHRDGRTRFQCDGNYDNYEPNGFEGPVQDSSYAEPPLSISGDMDRYNSHIGNDDYSQ
CEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHH
AGDLYRLMSVEERERLTSAIASTMHNLPKPLLEANLKHFHLCDPEYGEQLAAKVGLALSR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9358059 [H]