| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is murC
Identifier: 45657726
GI number: 45657726
Start: 2257649
End: 2259121
Strand: Reverse
Name: murC
Synonym: LIC11863
Alternate gene names: 45657726
Gene position: 2259121-2257649 (Counterclockwise)
Preceding gene: 45657727
Following gene: 45657725
Centisome position: 52.82
GC content: 36.25
Gene sequence:
>1473_bases TTGAAGATGGATTCAAAATCCTTTCAAAAACCGTTCTTTTTGGGAATCGGCGGTTCTGGAATGTCTTCTCTTGCGTTTTT ACTTTTGAGCAAGGGCTTTGAGGTAAGCGGATATGACGGTAAAAATTCCGGAATTGTAGAAAAATTGATTTTAAATGGAG CAAACGTATTCCATAAATCTGATATTTTAGAAGTGGAAAATTACAGTATAGCTGTGTATTCTTCTGCGATCCGATTGGAT AACCATCCTTTGGTGAAAAAGTTCAAAGAAAAAGGAATTCCTTTGATCCATCGATCGGAACTACTTCATAAAATCATGTC GGAGAAAAAACAAATTTCGATTGCAGGTTCGCATGGAAAAACGACTACAACTGCGATGACGGCGTTTTTATTGGAAAAGT GTGGAATGTCACCGTCCGTAATGGTAGGGGGAGAAGTAGCGTTTTTAGGTGGTAAAGGTGGTGTATGGGGAAAGGGAGAA TGGGGAGTATTTGAATCGGACGAATCGGATGGGACATTTAACAATCATTATGCGGAAATGAGAATTCTTACCAACGTAGA TGAGGATCATCTAGATTATTATCAAACTCGAGAAAATTTGTTGAATGCGTTCGTACGTTATATGGAAGGCGCATCCAGAA GATTGATTTTAAATTTAGACGATATAGGAATTAGGGATTCCATTAAACTTATACACGATCATTCTAAAATATTAGGATTT TCTAAATATAAAAATCCAGACGAATTTACGAGTGGTTTGTCTCGAAATTCAGAAAAATCAAAGGATGACTTAAAAAATTC GGATATTGCTGGGGCTGAAAAAACTTCTAAGGTTTTGTACGGCATCGATCCAGATAAAATTGTGTATTACACAATACAAT CCGGAATTCTGTATTTTTATTTTCAAAAAAAAGAATATTCTTTTTCTCTAAAATATCCAGGGGAACACTACTTAAAAAAT GCTTTGGCGGCGATCTTGGCCTGTTTTGAAACCGGAATTCCTCTTTCTGACTTGGTTTCTAAAATTTCAGAGTATTCCGG AGTAAACAGAAGGCTTGAATATTTAGGAAGTAAGAATGGGATTGAAGTTTATGACGATTACGGTCACCATCCCACTGAAA TCAAAGCAGTGATACAGTCTATGGAAGAGTTGAAAAAAGAAGGAAGGGCGGTCATATTATTTCAACCACATAGATATACT AGGACACAAAATCTTTATAAAGAGTTTGCAGAAAGTTTAGATTCGGGTGAGATCGTATTTCTTTTACCGATTTATTCTGC GGGAGAAGATCCTATCTACGGAGTGAAAGCGGAACTCATTTCAGATTTTATGAAGTTCCCCGCAAAAATTCTTCCTAAGG AAATTTCAGAAGGAATTTTCACATTGAAAAGTTTTTTAAAACCTGGAGATAAGTTAGTCACCCTAGGAGCGGGTAACGTA AGAGACTGGGGTTTAGCTTTTTTAAAAAATTAA
Upstream 100 bases:
>100_bases CAAATGACGTAAATTTGTTAAACGACATGTCGATTAGTTCTCTTGAATGTTCTCACGTGGACGCTTCTAAGGACACGGCT AAATACTTTTTCTCTCTCGA
Downstream 100 bases:
>100_bases ATTGTATTTAAAAAGTTACTGATTTAAAATACGAGTTCAGATTCTTCCGTTTAAAAAAACTTCTTGTATTTAATTTGATT CTCCTTAACGTTTCCCATCT
Product: UDP-N-acetylmuramate-alanine ligase
Products: NA
Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]
Number of amino acids: Translated: 490; Mature: 490
Protein sequence:
>490_residues MKMDSKSFQKPFFLGIGGSGMSSLAFLLLSKGFEVSGYDGKNSGIVEKLILNGANVFHKSDILEVENYSIAVYSSAIRLD NHPLVKKFKEKGIPLIHRSELLHKIMSEKKQISIAGSHGKTTTTAMTAFLLEKCGMSPSVMVGGEVAFLGGKGGVWGKGE WGVFESDESDGTFNNHYAEMRILTNVDEDHLDYYQTRENLLNAFVRYMEGASRRLILNLDDIGIRDSIKLIHDHSKILGF SKYKNPDEFTSGLSRNSEKSKDDLKNSDIAGAEKTSKVLYGIDPDKIVYYTIQSGILYFYFQKKEYSFSLKYPGEHYLKN ALAAILACFETGIPLSDLVSKISEYSGVNRRLEYLGSKNGIEVYDDYGHHPTEIKAVIQSMEELKKEGRAVILFQPHRYT RTQNLYKEFAESLDSGEIVFLLPIYSAGEDPIYGVKAELISDFMKFPAKILPKEISEGIFTLKSFLKPGDKLVTLGAGNV RDWGLAFLKN
Sequences:
>Translated_490_residues MKMDSKSFQKPFFLGIGGSGMSSLAFLLLSKGFEVSGYDGKNSGIVEKLILNGANVFHKSDILEVENYSIAVYSSAIRLD NHPLVKKFKEKGIPLIHRSELLHKIMSEKKQISIAGSHGKTTTTAMTAFLLEKCGMSPSVMVGGEVAFLGGKGGVWGKGE WGVFESDESDGTFNNHYAEMRILTNVDEDHLDYYQTRENLLNAFVRYMEGASRRLILNLDDIGIRDSIKLIHDHSKILGF SKYKNPDEFTSGLSRNSEKSKDDLKNSDIAGAEKTSKVLYGIDPDKIVYYTIQSGILYFYFQKKEYSFSLKYPGEHYLKN ALAAILACFETGIPLSDLVSKISEYSGVNRRLEYLGSKNGIEVYDDYGHHPTEIKAVIQSMEELKKEGRAVILFQPHRYT RTQNLYKEFAESLDSGEIVFLLPIYSAGEDPIYGVKAELISDFMKFPAKILPKEISEGIFTLKSFLKPGDKLVTLGAGNV RDWGLAFLKN >Mature_490_residues MKMDSKSFQKPFFLGIGGSGMSSLAFLLLSKGFEVSGYDGKNSGIVEKLILNGANVFHKSDILEVENYSIAVYSSAIRLD NHPLVKKFKEKGIPLIHRSELLHKIMSEKKQISIAGSHGKTTTTAMTAFLLEKCGMSPSVMVGGEVAFLGGKGGVWGKGE WGVFESDESDGTFNNHYAEMRILTNVDEDHLDYYQTRENLLNAFVRYMEGASRRLILNLDDIGIRDSIKLIHDHSKILGF SKYKNPDEFTSGLSRNSEKSKDDLKNSDIAGAEKTSKVLYGIDPDKIVYYTIQSGILYFYFQKKEYSFSLKYPGEHYLKN ALAAILACFETGIPLSDLVSKISEYSGVNRRLEYLGSKNGIEVYDDYGHHPTEIKAVIQSMEELKKEGRAVILFQPHRYT RTQNLYKEFAESLDSGEIVFLLPIYSAGEDPIYGVKAELISDFMKFPAKILPKEISEGIFTLKSFLKPGDKLVTLGAGNV RDWGLAFLKN
Specific function: Cell wall formation [H]
COG id: COG0773
COG function: function code M; UDP-N-acetylmuramate-alanine ligase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786279, Length=469, Percent_Identity=29.8507462686567, Blast_Score=183, Evalue=2e-47, Organism=Escherichia coli, GI1790680, Length=489, Percent_Identity=26.1758691206544, Blast_Score=130, Evalue=1e-31,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR016040 - InterPro: IPR005758 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.8 [H]
Molecular weight: Translated: 54829; Mature: 54829
Theoretical pI: Translated: 7.21; Mature: 7.21
Prosite motif: PS00012 PHOSPHOPANTETHEINE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKMDSKSFQKPFFLGIGGSGMSSLAFLLLSKGFEVSGYDGKNSGIVEKLILNGANVFHKS CCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHCCCCCEECC DILEVENYSIAVYSSAIRLDNHPLVKKFKEKGIPLIHRSELLHKIMSEKKQISIAGSHGK CCEEECCCEEEEEEEEEEECCCHHHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEECCCCC TTTTAMTAFLLEKCGMSPSVMVGGEVAFLGGKGGVWGKGEWGVFESDESDGTFNNHYAEM HHHHHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE RILTNVDEDHLDYYQTRENLLNAFVRYMEGASRRLILNLDDIGIRDSIKLIHDHSKILGF EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC SKYKNPDEFTSGLSRNSEKSKDDLKNSDIAGAEKTSKVLYGIDPDKIVYYTIQSGILYFY HHCCCHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCEEECCCCCCEEEEEEECCEEEEE FQKKEYSFSLKYPGEHYLKNALAAILACFETGIPLSDLVSKISEYSGVNRRLEYLGSKNG EEECCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCCC IEVYDDYGHHPTEIKAVIQSMEELKKEGRAVILFQPHRYTRTQNLYKEFAESLDSGEIVF CEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEE LLPIYSAGEDPIYGVKAELISDFMKFPAKILPKEISEGIFTLKSFLKPGDKLVTLGAGNV EEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC RDWGLAFLKN CHHHHHHHCC >Mature Secondary Structure MKMDSKSFQKPFFLGIGGSGMSSLAFLLLSKGFEVSGYDGKNSGIVEKLILNGANVFHKS CCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHCCCCCEECC DILEVENYSIAVYSSAIRLDNHPLVKKFKEKGIPLIHRSELLHKIMSEKKQISIAGSHGK CCEEECCCEEEEEEEEEEECCCHHHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEECCCCC TTTTAMTAFLLEKCGMSPSVMVGGEVAFLGGKGGVWGKGEWGVFESDESDGTFNNHYAEM HHHHHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE RILTNVDEDHLDYYQTRENLLNAFVRYMEGASRRLILNLDDIGIRDSIKLIHDHSKILGF EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC SKYKNPDEFTSGLSRNSEKSKDDLKNSDIAGAEKTSKVLYGIDPDKIVYYTIQSGILYFY HHCCCHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCEEECCCCCCEEEEEEECCEEEEE FQKKEYSFSLKYPGEHYLKNALAAILACFETGIPLSDLVSKISEYSGVNRRLEYLGSKNG EEECCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCCC IEVYDDYGHHPTEIKAVIQSMEELKKEGRAVILFQPHRYTRTQNLYKEFAESLDSGEIVF CEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEE LLPIYSAGEDPIYGVKAELISDFMKFPAKILPKEISEGIFTLKSFLKPGDKLVTLGAGNV EEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC RDWGLAFLKN CHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA