Click here to switch to the map view.

The map label for this gene is murG

Identifier: 45657727

GI number: 45657727

Start: 2259118

End: 2260194

Strand: Reverse

Name: murG

Synonym: LIC11864

Alternate gene names: 45657727

Gene position: 2260194-2259118 (Counterclockwise)

Preceding gene: 45657728

Following gene: 45657726

Centisome position: 52.84

GC content: 36.77

Gene sequence:

>1077_bases
ATGAAATCGATTGTAATCGTGGCCGGCGGGACCGGAGGACATATTTCACCGGGAGTTGCACTTGCGGAAGTATTGACTGA
ATTGAAAGAAAAAATCGGATACGAAAATTTGTATTTATATTCTTTGGTTCGTAATAAAAATAATCCAGATTTAGAACAAG
CTCCTTGTCCGGTTTTATGGCATAATCTTCCACCTCTTTCCAGTAATTTTTTTCTGTTTCCTATTCGATATACTATCCAA
ATTATAAAGACTTTTTTTATATTCAAAAAATTAAATATAGATGTAGTCATAGGAATGGGGGGATACTCCACGGTGTCTTC
TATTCTTTATGGAATATTTTTTAGAAAAAAAATCTATCTGTGTGAACAAAATACAATTCCAGGAAATGTAAATCGATTGT
TCTTCCGGTTTGCGAGCAAAGTGGCGTTTAGTTTACCGCCTAAAAATTCTAAAATTCCATGCGATTATCAAGTATTAGGA
AATCCTCTTCGAAAAAAAACGATCCCTAAAATGTCTCTTAAGTTTTTTGAAAAATACGACACTAAAAAAAAGAAACAATT
TAATGTGCTTGTGATGGGAGGAAGTCAAGGTGCGAGACAGATCAATAATATTGTAATCGCTTTGATGAGTCACGAGGAAA
TCAACAAGCAGTTCCGATTTAGAGTGCTAACTGGTTCGGCTCTTTACGAAGAGGTTTCTAAAAAATCCAAAAAGGACGCA
GAGCTTATCTCTTATTCTGACAATATGAAGGAGCACTATGAATGGGCAAACTTTGTTATTGCTCGTTCTGGCTCGGGGGT
TCTTTCTGAGTGCGCCGCATTTGCATTGCCTATGATTTTAATACCTTATCCTTATGCAAAAGACGATCACCAAATGGCAA
ACGCAAAATATTTTGAACTTAACGGAGCGGCCATCGTGGTCGATCAAAAAGACGAGGATGAGTCTCATCTTTTTCGTGTT
TTAGACCAAATGGCAAATGACGTAAATTTGTTAAACGACATGTCGATTAGTTCTCTTGAATGTTCTCACGTGGACGCTTC
TAAGGACACGGCTAAATACTTTTTCTCTCTCGATTGA

Upstream 100 bases:

>100_bases
TCAGTTTGCCGTTTGTGAGTTACGGAGGATCTTCAATTCTGATCGTATTAATTTCTCTCGGAATTCTTGTCAATATTACT
CGAAAGGAAAATCTGGGATT

Downstream 100 bases:

>100_bases
AGATGGATTCAAAATCCTTTCAAAAACCGTTCTTTTTGGGAATCGGCGGTTCTGGAATGTCTTCTCTTGCGTTTTTACTT
TTGAGCAAGGGCTTTGAGGT

Product: UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKSIVIVAGGTGGHISPGVALAEVLTELKEKIGYENLYLYSLVRNKNNPDLEQAPCPVLWHNLPPLSSNFFLFPIRYTIQ
IIKTFFIFKKLNIDVVIGMGGYSTVSSILYGIFFRKKIYLCEQNTIPGNVNRLFFRFASKVAFSLPPKNSKIPCDYQVLG
NPLRKKTIPKMSLKFFEKYDTKKKKQFNVLVMGGSQGARQINNIVIALMSHEEINKQFRFRVLTGSALYEEVSKKSKKDA
ELISYSDNMKEHYEWANFVIARSGSGVLSECAAFALPMILIPYPYAKDDHQMANAKYFELNGAAIVVDQKDEDESHLFRV
LDQMANDVNLLNDMSISSLECSHVDASKDTAKYFFSLD

Sequences:

>Translated_358_residues
MKSIVIVAGGTGGHISPGVALAEVLTELKEKIGYENLYLYSLVRNKNNPDLEQAPCPVLWHNLPPLSSNFFLFPIRYTIQ
IIKTFFIFKKLNIDVVIGMGGYSTVSSILYGIFFRKKIYLCEQNTIPGNVNRLFFRFASKVAFSLPPKNSKIPCDYQVLG
NPLRKKTIPKMSLKFFEKYDTKKKKQFNVLVMGGSQGARQINNIVIALMSHEEINKQFRFRVLTGSALYEEVSKKSKKDA
ELISYSDNMKEHYEWANFVIARSGSGVLSECAAFALPMILIPYPYAKDDHQMANAKYFELNGAAIVVDQKDEDESHLFRV
LDQMANDVNLLNDMSISSLECSHVDASKDTAKYFFSLD
>Mature_358_residues
MKSIVIVAGGTGGHISPGVALAEVLTELKEKIGYENLYLYSLVRNKNNPDLEQAPCPVLWHNLPPLSSNFFLFPIRYTIQ
IIKTFFIFKKLNIDVVIGMGGYSTVSSILYGIFFRKKIYLCEQNTIPGNVNRLFFRFASKVAFSLPPKNSKIPCDYQVLG
NPLRKKTIPKMSLKFFEKYDTKKKKQFNVLVMGGSQGARQINNIVIALMSHEEINKQFRFRVLTGSALYEEVSKKSKKDA
ELISYSDNMKEHYEWANFVIARSGSGVLSECAAFALPMILIPYPYAKDDHQMANAKYFELNGAAIVVDQKDEDESHLFRV
LDQMANDVNLLNDMSISSLECSHVDASKDTAKYFFSLD

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=318, Percent_Identity=29.2452830188679, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 40528; Mature: 40528

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIVIVAGGTGGHISPGVALAEVLTELKEKIGYENLYLYSLVRNKNNPDLEQAPCPVLW
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHCCCCEEE
HNLPPLSSNFFLFPIRYTIQIIKTFFIFKKLNIDVVIGMGGYSTVSSILYGIFFRKKIYL
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHEEEE
CEQNTIPGNVNRLFFRFASKVAFSLPPKNSKIPCDYQVLGNPLRKKTIPKMSLKFFEKYD
EECCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCHHHHCCCHHHHHHHHHHC
TKKKKQFNVLVMGGSQGARQINNIVIALMSHEEINKQFRFRVLTGSALYEEVSKKSKKDA
CCCCCEEEEEEEECCCCHHHHHHEEEEEECHHHHCCEEEEEEEECHHHHHHHHHHCCCCH
ELISYSDNMKEHYEWANFVIARSGSGVLSECAAFALPMILIPYPYAKDDHQMANAKYFEL
HHHHCCCCHHHHHHHHHEEEEECCCCHHHHHHHHHCCHHEECCCCCCCCCHHCCCEEEEE
NGAAIVVDQKDEDESHLFRVLDQMANDVNLLNDMSISSLECSHVDASKDTAKYFFSLD
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MKSIVIVAGGTGGHISPGVALAEVLTELKEKIGYENLYLYSLVRNKNNPDLEQAPCPVLW
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHCCCCEEE
HNLPPLSSNFFLFPIRYTIQIIKTFFIFKKLNIDVVIGMGGYSTVSSILYGIFFRKKIYL
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHEEEE
CEQNTIPGNVNRLFFRFASKVAFSLPPKNSKIPCDYQVLGNPLRKKTIPKMSLKFFEKYD
EECCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHCCCHHHHCCCHHHHHHHHHHC
TKKKKQFNVLVMGGSQGARQINNIVIALMSHEEINKQFRFRVLTGSALYEEVSKKSKKDA
CCCCCEEEEEEEECCCCHHHHHHEEEEEECHHHHCCEEEEEEEECHHHHHHHHHHCCCCH
ELISYSDNMKEHYEWANFVIARSGSGVLSECAAFALPMILIPYPYAKDDHQMANAKYFEL
HHHHCCCCHHHHHHHHHEEEEECCCCHHHHHHHHHCCHHEECCCCCCCCCHHCCCEEEEE
NGAAIVVDQKDEDESHLFRVLDQMANDVNLLNDMSISSLECSHVDASKDTAKYFFSLD
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA