| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is kdsA
Identifier: 45657414
GI number: 45657414
Start: 1903682
End: 1904551
Strand: Direct
Name: kdsA
Synonym: LIC11541
Alternate gene names: 45657414
Gene position: 1903682-1904551 (Clockwise)
Preceding gene: 45657413
Following gene: 45657415
Centisome position: 44.51
GC content: 37.7
Gene sequence:
>870_bases ATGAACATGAAAGACAATACTTGTACAAAAAGAGATTTTTTAAACGGAACTAAAATAGGAGGAGACGAACCTTTTTTTCT AATTTCCGGTCCTTGTGTTATGGAAAATAGGGATCTATTGGATCGGGTCTGCGCCGAGATGATAGAAGTTTGTGGAGAAT TAAAAATTCCTTATATTTTTAAAAGTAGTTTTGATAAGGCCAATCGTTCTTCCGTAAATTCCTATCGTGGACCAGGGCTT GCAGAAGGTATTAAAAATTTAGAATATATTAAAAATAAGTACAACGTTCCTGTTTTGACGGATATTCACGAAACCTCTCA GATTTCTCCTTTGAAAGACGTGATAGACGTATATCAGATCCCTGCGTTCTTGTGTAGACAAACAGATCTAATTTCACAAT CCGCTCAAACAGGTAAATGGGTAAACGTAAAAAAAGGCCAATTTCTTGCACCTGCGGATACGCGTCATATCGCGGTTAAG ATGAACGAATCCGGAAATAATAAGCTACTCGTAACCGAAAGAGGAACTTCGTTTGGTTACGGAAATTTAATATTCGATGG AAGAGCAATTCCGATCATTCACGGATTTGATATTCCTCTTGTATTTGATGCGACACATTCTGCACAACTTCCCGGAGCTG CTGGAAACAGTACTGGTGGACAAAGAGAATTTATTCCGAGTATTCTTCGTTCTGCCGTTTCTTTTGGTATTGAAGGTATT TTTATGGAAGTACATCCAGATCCACCAAACGCACTTTCGGATGCCACGACTCAGTATCCACTTTCTCAGATTAAGAGCCT TTTGAAAGAGATGATCGGTCTAGATCGTTATATTAAAAAAGAAATTCTAATTTCTAGAAGCAGCTTATAA
Upstream 100 bases:
>100_bases TAGGAGTTCAGTTTCATCCTGAATTTCAGTCTAAACCTACTTTACCTCATCCCTTATTCGCTGGATTTATCCGCGCCTCT GTGAAATACTCTAAAAAAGG
Downstream 100 bases:
>100_bases TCGGTTTTTTTATGAAAAATAAAAACAACAATCGGATTTTAGTTTTTTTGATTTCGGTTGTTTGCGGATTTTTTCTAATC ATATTCGAAAATTGTAAAAA
Product: 2-dehydro-3-deoxyphosphooctonate aldolase
Products: NA
Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]
Number of amino acids: Translated: 289; Mature: 289
Protein sequence:
>289_residues MNMKDNTCTKRDFLNGTKIGGDEPFFLISGPCVMENRDLLDRVCAEMIEVCGELKIPYIFKSSFDKANRSSVNSYRGPGL AEGIKNLEYIKNKYNVPVLTDIHETSQISPLKDVIDVYQIPAFLCRQTDLISQSAQTGKWVNVKKGQFLAPADTRHIAVK MNESGNNKLLVTERGTSFGYGNLIFDGRAIPIIHGFDIPLVFDATHSAQLPGAAGNSTGGQREFIPSILRSAVSFGIEGI FMEVHPDPPNALSDATTQYPLSQIKSLLKEMIGLDRYIKKEILISRSSL
Sequences:
>Translated_289_residues MNMKDNTCTKRDFLNGTKIGGDEPFFLISGPCVMENRDLLDRVCAEMIEVCGELKIPYIFKSSFDKANRSSVNSYRGPGL AEGIKNLEYIKNKYNVPVLTDIHETSQISPLKDVIDVYQIPAFLCRQTDLISQSAQTGKWVNVKKGQFLAPADTRHIAVK MNESGNNKLLVTERGTSFGYGNLIFDGRAIPIIHGFDIPLVFDATHSAQLPGAAGNSTGGQREFIPSILRSAVSFGIEGI FMEVHPDPPNALSDATTQYPLSQIKSLLKEMIGLDRYIKKEILISRSSL >Mature_289_residues MNMKDNTCTKRDFLNGTKIGGDEPFFLISGPCVMENRDLLDRVCAEMIEVCGELKIPYIFKSSFDKANRSSVNSYRGPGL AEGIKNLEYIKNKYNVPVLTDIHETSQISPLKDVIDVYQIPAFLCRQTDLISQSAQTGKWVNVKKGQFLAPADTRHIAVK MNESGNNKLLVTERGTSFGYGNLIFDGRAIPIIHGFDIPLVFDATHSAQLPGAAGNSTGGQREFIPSILRSAVSFGIEGI FMEVHPDPPNALSDATTQYPLSQIKSLLKEMIGLDRYIKKEILISRSSL
Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]
COG id: COG2877
COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the kdsA family [H]
Homologues:
Organism=Escherichia coli, GI1787466, Length=263, Percent_Identity=43.3460076045627, Blast_Score=246, Evalue=2e-66,
Paralogues:
None
Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013785 - InterPro: IPR006218 - InterPro: IPR006269 [H]
Pfam domain/function: PF00793 DAHP_synth_1 [H]
EC number: =2.5.1.55 [H]
Molecular weight: Translated: 31949; Mature: 31949
Theoretical pI: Translated: 7.45; Mature: 7.45
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNMKDNTCTKRDFLNGTKIGGDEPFFLISGPCVMENRDLLDRVCAEMIEVCGELKIPYIF CCCCCCCCHHHHCCCCCCCCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHCCCCCCEEE KSSFDKANRSSVNSYRGPGLAEGIKNLEYIKNKYNVPVLTDIHETSQISPLKDVIDVYQI CCCCCCCCHHHCHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHH PAFLCRQTDLISQSAQTGKWVNVKKGQFLAPADTRHIAVKMNESGNNKLLVTERGTSFGY HHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCEEEEEECCCCCCEEEEEECCCCCCC GNLIFDGRAIPIIHGFDIPLVFDATHSAQLPGAAGNSTGGQREFIPSILRSAVSFGIEGI CCEEECCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE FMEVHPDPPNALSDATTQYPLSQIKSLLKEMIGLDRYIKKEILISRSSL EEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MNMKDNTCTKRDFLNGTKIGGDEPFFLISGPCVMENRDLLDRVCAEMIEVCGELKIPYIF CCCCCCCCHHHHCCCCCCCCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHCCCCCCEEE KSSFDKANRSSVNSYRGPGLAEGIKNLEYIKNKYNVPVLTDIHETSQISPLKDVIDVYQI CCCCCCCCHHHCHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHH PAFLCRQTDLISQSAQTGKWVNVKKGQFLAPADTRHIAVKMNESGNNKLLVTERGTSFGY HHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCEEEEEECCCCCCEEEEEECCCCCCC GNLIFDGRAIPIIHGFDIPLVFDATHSAQLPGAAGNSTGGQREFIPSILRSAVSFGIEGI CCEEECCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE FMEVHPDPPNALSDATTQYPLSQIKSLLKEMIGLDRYIKKEILISRSSL EEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA