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The map label for this gene is kamA [H]

Identifier: 45657183

GI number: 45657183

Start: 1610517

End: 1611806

Strand: Direct

Name: kamA [H]

Synonym: LIC11303

Alternate gene names: 45657183

Gene position: 1610517-1611806 (Clockwise)

Preceding gene: 45657179

Following gene: 45657184

Centisome position: 37.65

GC content: 36.67

Gene sequence:

>1290_bases
TTGATTTTCCCCGGACTCGAAGAAAATAGGAACAACCGAATGAATACTTCCCATTCTTTTGTACAAAAATCTAAAGGAGA
AAGTTTTGTAAATCGTTCTCGGTTATTTTCGTCCTTTGATTGGACCGATTACAAGGCACAACTTCAGAATAGAGTAAAAG
GTTTTGAACTAGAACGTTATTTCGATTTAACGGAGAGCGAAAAAATTGGAATTGAAAACACAATTCGTTTAAACGTTTCG
GCAACTCCATATTACATTTCTCTTGCAGACCCAGAAGATCCAAATTGTCCGATTCGAAAAATGATTCTTCCCAGAGAAGA
CGAATGTATTTTTTCTCCGGAAGAGTCCCCTGATCCTTTACACGAGGAGCGATTGTCTCCTGTAAAAGGTTTAACACATA
TGTATCCAGATCGGGTTCTTCTTTTTACCAACCATGAATGTTCTGTATATTGTAGACATTGTATGAGAGGTCGTAAGGTT
TCCGATTCCAAAGAAAGAATGCTTACGGAGGATTTGGAAATTTGTTTCGACTACATCAAATCTCATCCAGAAATTACCGA
CGTCGTATTATCTGGGGGAGATCCCTTGAATCTAAGTGATTCTAAAATCGACTGGATTTTGGAACGATTGGAAAAAATTG
AACACGTTAAGATTTGTAGGTTAGGAACTCGTAATCCGGTCACTCTTCCATTTAGAGTTACATTTGATCTTTGTAATATA
ATAGAATCTCATAATACCGACAGACTTTCCATTTTTTGTAATACTCAATTTAATCACTCTAAAGAATGTACTCCCGAAGC
AAAAGAAGCAATTTTAAAACTTTTGAAAGCGGGAGTGAACGTAGGCAACCAATGTGTTCTTTTAAAAGAAGTTAATGATT
CCGGACAAACTATGTTAGAACTTCATAAAAAACTATTGGAGTTGCGAGTTCGAGCTTATTATATGTACGATCCGGAGTTG
ATTCCCGGTTCTAGAGGTTTTAGAACTCCTCTTGCTAAAGGAATTGAAATCATTGAATTTATGAGAGGTAAAATTGGTGG
GATGGGAATTCCACAATTTGTAAACGATCTTCCTGGAGGAGGAGGAAAAATTACTTTAACTCCGAATTGGTATTTGGGTT
TTTACAAACCGGAGAGGATACACGTTTTCAAGTCTGCGTTACGCGGAACCTATCATTTCAGTCCGGAACCAATCGATTCT
AAGATGGAGGAATTTTATCCGGAAATTTCTTCAGAAATCTGGGAAAGAGTTTTTTCTAATTCTTTCGGAATCTACAAATC
AAATGAATAA

Upstream 100 bases:

>100_bases
GTACCGTCTACATCGAACGCAAGGGCTTGGAGAGATTCTACTGAAAATACAGTCATTCTAAGGACAGTTTTAGAAAACGA
ATCCTTTTGGCAACCTTTGC

Downstream 100 bases:

>100_bases
AATGACTCCTACTGTTTTGGTTTATGCAGATCTACACGAATTTGAGGGAAATTTTCCGGAAATTTATAAACAGGAATGGG
AGTCCAAGAAGTCAGTGGAC

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MIFPGLEENRNNRMNTSHSFVQKSKGESFVNRSRLFSSFDWTDYKAQLQNRVKGFELERYFDLTESEKIGIENTIRLNVS
ATPYYISLADPEDPNCPIRKMILPREDECIFSPEESPDPLHEERLSPVKGLTHMYPDRVLLFTNHECSVYCRHCMRGRKV
SDSKERMLTEDLEICFDYIKSHPEITDVVLSGGDPLNLSDSKIDWILERLEKIEHVKICRLGTRNPVTLPFRVTFDLCNI
IESHNTDRLSIFCNTQFNHSKECTPEAKEAILKLLKAGVNVGNQCVLLKEVNDSGQTMLELHKKLLELRVRAYYMYDPEL
IPGSRGFRTPLAKGIEIIEFMRGKIGGMGIPQFVNDLPGGGGKITLTPNWYLGFYKPERIHVFKSALRGTYHFSPEPIDS
KMEEFYPEISSEIWERVFSNSFGIYKSNE

Sequences:

>Translated_429_residues
MIFPGLEENRNNRMNTSHSFVQKSKGESFVNRSRLFSSFDWTDYKAQLQNRVKGFELERYFDLTESEKIGIENTIRLNVS
ATPYYISLADPEDPNCPIRKMILPREDECIFSPEESPDPLHEERLSPVKGLTHMYPDRVLLFTNHECSVYCRHCMRGRKV
SDSKERMLTEDLEICFDYIKSHPEITDVVLSGGDPLNLSDSKIDWILERLEKIEHVKICRLGTRNPVTLPFRVTFDLCNI
IESHNTDRLSIFCNTQFNHSKECTPEAKEAILKLLKAGVNVGNQCVLLKEVNDSGQTMLELHKKLLELRVRAYYMYDPEL
IPGSRGFRTPLAKGIEIIEFMRGKIGGMGIPQFVNDLPGGGGKITLTPNWYLGFYKPERIHVFKSALRGTYHFSPEPIDS
KMEEFYPEISSEIWERVFSNSFGIYKSNE
>Mature_429_residues
MIFPGLEENRNNRMNTSHSFVQKSKGESFVNRSRLFSSFDWTDYKAQLQNRVKGFELERYFDLTESEKIGIENTIRLNVS
ATPYYISLADPEDPNCPIRKMILPREDECIFSPEESPDPLHEERLSPVKGLTHMYPDRVLLFTNHECSVYCRHCMRGRKV
SDSKERMLTEDLEICFDYIKSHPEITDVVLSGGDPLNLSDSKIDWILERLEKIEHVKICRLGTRNPVTLPFRVTFDLCNI
IESHNTDRLSIFCNTQFNHSKECTPEAKEAILKLLKAGVNVGNQCVLLKEVNDSGQTMLELHKKLLELRVRAYYMYDPEL
IPGSRGFRTPLAKGIEIIEFMRGKIGGMGIPQFVNDLPGGGGKITLTPNWYLGFYKPERIHVFKSALRGTYHFSPEPIDS
KMEEFYPEISSEIWERVFSNSFGIYKSNE

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=329, Percent_Identity=30.3951367781155, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 49545; Mature: 49545

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFPGLEENRNNRMNTSHSFVQKSKGESFVNRSRLFSSFDWTDYKAQLQNRVKGFELERY
CCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEHHHH
FDLTESEKIGIENTIRLNVSATPYYISLADPEDPNCPIRKMILPREDECIFSPEESPDPL
CCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCHHHCCCCCCCCEEECCCCCCCCH
HEERLSPVKGLTHMYPDRVLLFTNHECSVYCRHCMRGRKVSDSKERMLTEDLEICFDYIK
HHHHCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
SHPEITDVVLSGGDPLNLSDSKIDWILERLEKIEHVKICRLGTRNPVTLPFRVTFDLCNI
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEEHHHHHHH
IESHNTDRLSIFCNTQFNHSKECTPEAKEAILKLLKAGVNVGNQCVLLKEVNDSGQTMLE
HHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
LHKKLLELRVRAYYMYDPELIPGSRGFRTPLAKGIEIIEFMRGKIGGMGIPQFVNDLPGG
HHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
GGKITLTPNWYLGFYKPERIHVFKSALRGTYHFSPEPIDSKMEEFYPEISSEIWERVFSN
CCEEEECCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
SFGIYKSNE
CCCCEECCC
>Mature Secondary Structure
MIFPGLEENRNNRMNTSHSFVQKSKGESFVNRSRLFSSFDWTDYKAQLQNRVKGFELERY
CCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEHHHH
FDLTESEKIGIENTIRLNVSATPYYISLADPEDPNCPIRKMILPREDECIFSPEESPDPL
CCCCCCCCCCCCEEEEEEEECCCEEEEECCCCCCCCCHHHCCCCCCCCEEECCCCCCCCH
HEERLSPVKGLTHMYPDRVLLFTNHECSVYCRHCMRGRKVSDSKERMLTEDLEICFDYIK
HHHHCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
SHPEITDVVLSGGDPLNLSDSKIDWILERLEKIEHVKICRLGTRNPVTLPFRVTFDLCNI
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEEHHHHHHH
IESHNTDRLSIFCNTQFNHSKECTPEAKEAILKLLKAGVNVGNQCVLLKEVNDSGQTMLE
HHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
LHKKLLELRVRAYYMYDPELIPGSRGFRTPLAKGIEIIEFMRGKIGGMGIPQFVNDLPGG
HHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCC
GGKITLTPNWYLGFYKPERIHVFKSALRGTYHFSPEPIDSKMEEFYPEISSEIWERVFSN
CCEEEECCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
SFGIYKSNE
CCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]