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The map label for this gene is ddl

Identifier: 45657184

GI number: 45657184

Start: 1611799

End: 1612923

Strand: Direct

Name: ddl

Synonym: LIC11304

Alternate gene names: 45657184

Gene position: 1611799-1612923 (Clockwise)

Preceding gene: 45657183

Following gene: 45657185

Centisome position: 37.68

GC content: 34.31

Gene sequence:

>1125_bases
ATGAATAAAATGACTCCTACTGTTTTGGTTTATGCAGATCTACACGAATTTGAGGGAAATTTTCCGGAAATTTATAAACA
GGAATGGGAGTCCAAGAAGTCAGTGGACGCAATTTTAGAATTGTTAAACGAAGTCGGAGAAAGTATCGAACTGGTAGTAA
CTCCAAATGAACTTCTGGAAAAATTAAAATGTTATTGTGATTTGGACTTTTCTAAACGTCCCGTAATTTTTCATTTAATG
GAAGGGTTTTGTTCTAGAAATAGAGAATCTTTGATTCCTGCCGTAGCCGAATTATTCGGTTTTCCTCATACTGGTTCGGA
CTCGTATTCTCAAAATGTTTCCTTAGATAAAAATTTAACCCGAATTTTTGCACAATCGATAGGTGTTCCTGTTGCATCAG
GATTTTGGATTCGCTCTAAGGATGTTTTATTTAAAGAATTACTACAATTGGAATGTAATTCTGAAATTAAAAAAAGGTTT
TCTTTTTCAAAAGGGAATGAACTCAATCTGAAAAATTTTTCCTTCCCCGCTTTTATTAAACCTGCGGGAGAAGGTTCTAG
TCTTGGAATCGGAGAAAAAAATATCATTTATAGTTTTGAAGAACTGAATACTTTATTGTCTGAAGCTCCGGAAATTTTTT
TCCCATATCTTTTGGAAGAATACTTAACAGGAAACGAATATACGATTTCTGTAATTGGTTCTGCCACTTTTGGTTATAAG
GTAAGTTCTGCCGGACGATTGATATTACGAGAAGATTTAAAAGTCGAAGATGTATACGGAGAAAAAACGAAATCTAAAAG
TATAATGCCCGAGACTCTCGTATTTGATTGTCCTAAAGATTTGGAAGTTATAATTCAACAACAGAGTGTGTTATTTTGTG
AATCTCTTGGGACCTCCGGACCTGCGAGACTTGACTGGAAATTGGATTCCTTAGGGAATCCTTTTTTTTTAGAAATGAAT
CTAACCCCTGGATTGTCTCCGTTTTATTCCACGTTTCCGATTTGTTATCGTCATAGCCTTGGGGACGAAAAAAATTTGTT
TCAAGAGATTCTAAAAATTGCGCGTTTGGATTTCGAGACTGATCGATTTTTATATTCTAAAAATAAAATTCGGAATCTAA
TATAA

Upstream 100 bases:

>100_bases
CCGGAACCAATCGATTCTAAGATGGAGGAATTTTATCCGGAAATTTCTTCAGAAATCTGGGAAAGAGTTTTTTCTAATTC
TTTCGGAATCTACAAATCAA

Downstream 100 bases:

>100_bases
AATTATAGATTTATGCAATCAATCAATACTGCTTCAACTTTTAGAAAAACCTTGGAAGAATCTGTTCGAAATCATCCAGT
TCTTACTTTTAATCTTTGGT

Product: d-alanine--d-alanine ligase

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MNKMTPTVLVYADLHEFEGNFPEIYKQEWESKKSVDAILELLNEVGESIELVVTPNELLEKLKCYCDLDFSKRPVIFHLM
EGFCSRNRESLIPAVAELFGFPHTGSDSYSQNVSLDKNLTRIFAQSIGVPVASGFWIRSKDVLFKELLQLECNSEIKKRF
SFSKGNELNLKNFSFPAFIKPAGEGSSLGIGEKNIIYSFEELNTLLSEAPEIFFPYLLEEYLTGNEYTISVIGSATFGYK
VSSAGRLILREDLKVEDVYGEKTKSKSIMPETLVFDCPKDLEVIIQQQSVLFCESLGTSGPARLDWKLDSLGNPFFLEMN
LTPGLSPFYSTFPICYRHSLGDEKNLFQEILKIARLDFETDRFLYSKNKIRNLI

Sequences:

>Translated_374_residues
MNKMTPTVLVYADLHEFEGNFPEIYKQEWESKKSVDAILELLNEVGESIELVVTPNELLEKLKCYCDLDFSKRPVIFHLM
EGFCSRNRESLIPAVAELFGFPHTGSDSYSQNVSLDKNLTRIFAQSIGVPVASGFWIRSKDVLFKELLQLECNSEIKKRF
SFSKGNELNLKNFSFPAFIKPAGEGSSLGIGEKNIIYSFEELNTLLSEAPEIFFPYLLEEYLTGNEYTISVIGSATFGYK
VSSAGRLILREDLKVEDVYGEKTKSKSIMPETLVFDCPKDLEVIIQQQSVLFCESLGTSGPARLDWKLDSLGNPFFLEMN
LTPGLSPFYSTFPICYRHSLGDEKNLFQEILKIARLDFETDRFLYSKNKIRNLI
>Mature_374_residues
MNKMTPTVLVYADLHEFEGNFPEIYKQEWESKKSVDAILELLNEVGESIELVVTPNELLEKLKCYCDLDFSKRPVIFHLM
EGFCSRNRESLIPAVAELFGFPHTGSDSYSQNVSLDKNLTRIFAQSIGVPVASGFWIRSKDVLFKELLQLECNSEIKKRF
SFSKGNELNLKNFSFPAFIKPAGEGSSLGIGEKNIIYSFEELNTLLSEAPEIFFPYLLEEYLTGNEYTISVIGSATFGYK
VSSAGRLILREDLKVEDVYGEKTKSKSIMPETLVFDCPKDLEVIIQQQSVLFCESLGTSGPARLDWKLDSLGNPFFLEMN
LTPGLSPFYSTFPICYRHSLGDEKNLFQEILKIARLDFETDRFLYSKNKIRNLI

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Escherichia coli, GI1786280, Length=308, Percent_Identity=25.6493506493506, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 42571; Mature: 42571

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKMTPTVLVYADLHEFEGNFPEIYKQEWESKKSVDAILELLNEVGESIELVVTPNELLE
CCCCCCEEEEEEEHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEEECHHHHHH
KLKCYCDLDFSKRPVIFHLMEGFCSRNRESLIPAVAELFGFPHTGSDSYSQNVSLDKNLT
HHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
RIFAQSIGVPVASGFWIRSKDVLFKELLQLECNSEIKKRFSFSKGNELNLKNFSFPAFIK
HHHHHHCCCCCCCCCEECCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCEEEE
PAGEGSSLGIGEKNIIYSFEELNTLLSEAPEIFFPYLLEEYLTGNEYTISVIGSATFGYK
CCCCCCCCCCCCCHHEEEHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
VSSAGRLILREDLKVEDVYGEKTKSKSIMPETLVFDCPKDLEVIIQQQSVLFCESLGTSG
ECCCCCEEEECCCCEEHHCCCCCCCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHCCCCC
PARLDWKLDSLGNPFFLEMNLTPGLSPFYSTFPICYRHSLGDEKNLFQEILKIARLDFET
CCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCH
DRFLYSKNKIRNLI
HHHHHHHHHHHHCC
>Mature Secondary Structure
MNKMTPTVLVYADLHEFEGNFPEIYKQEWESKKSVDAILELLNEVGESIELVVTPNELLE
CCCCCCEEEEEEEHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEEECHHHHHH
KLKCYCDLDFSKRPVIFHLMEGFCSRNRESLIPAVAELFGFPHTGSDSYSQNVSLDKNLT
HHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
RIFAQSIGVPVASGFWIRSKDVLFKELLQLECNSEIKKRFSFSKGNELNLKNFSFPAFIK
HHHHHHCCCCCCCCCEECCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCEEEE
PAGEGSSLGIGEKNIIYSFEELNTLLSEAPEIFFPYLLEEYLTGNEYTISVIGSATFGYK
CCCCCCCCCCCCCHHEEEHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
VSSAGRLILREDLKVEDVYGEKTKSKSIMPETLVFDCPKDLEVIIQQQSVLFCESLGTSG
ECCCCCEEEECCCCEEHHCCCCCCCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHCCCCC
PARLDWKLDSLGNPFFLEMNLTPGLSPFYSTFPICYRHSLGDEKNLFQEILKIARLDFET
CCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCH
DRFLYSKNKIRNLI
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA