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The map label for this gene is zraS [C]

Identifier: 45657086

GI number: 45657086

Start: 1481329

End: 1482834

Strand: Direct

Name: zraS [C]

Synonym: LIC11202

Alternate gene names: 45657086

Gene position: 1481329-1482834 (Clockwise)

Preceding gene: 45657085

Following gene: 45657087

Centisome position: 34.63

GC content: 32.47

Gene sequence:

>1506_bases
TTGAAATCGTGGAGCTTCCAGTTGTTTAGCGATGAGATTTCGGTTTGTTTGATTGAGGACGATGACGAAGATGCGATTCT
TTTTCGGGAATATTTAGAAGAGATTCCGTTTCCGAAATACAAAGTCACACGTTTTAAAGACTTTCCGAGTTTGTTTGTAG
ATATAGAAAAAAACCCTTCAAAATATACAATTTATGTGGTTGATCATTTTTTAGGTCTACAAACTGGATTCGAAATTTTG
AATGAGATCCGCAAAGTAGTCGGTTCCGTTTCTGCGGTTTTGATTTCCGGAATTTCAAAAGAAGAAATAGAAAGGATTAC
AAGTGAAGGTGGATTTCAAGGATATTTGGAAAAGAAAAATCTTTCTGCGTTTACTCTGGCAAAAACTTTCTTTGAAGTTT
TGAAAGAAAAAGAGGATTTGAGATCGGAAACTGATATTTTTCTTTTAAAGATGGAAATTATATCCCAATTTTCCGGAGGG
GTTGCACACGATTTTAATAATATTCTAAATATCATCGTCGCCAATTTGGACATTCTAGAAATGAAATGTAAGGATCAACC
GGAGGTTTTAAATAGAATTCAATCTGCACAAAACGCCGTTTTAAGAGGTGCAGAGGTAAATAAGAAGTTATTAAATTTTT
CTAGAAAACAATCCTTACATCCGGAAATAATCAATCCAAATCTGTTTATAGCCGATTTTTTAGAAAAATCTAAAAACATT
TTTTCAGAAAACGTTCAGTTAGTTTTTAACCCTGGTTCACAAGAAGTTTTTTGTAAAGTCGATCAAACCGAATTTGCAAA
TTGTATTATGAATTTATTACAAAATGCGAATGAAGCGTCTGGAGGAAAAATTTTGATCGAAACTGATACAATCGTCTTAA
ATTCTAAAAATAAATCTCTTGGGTTAAAAGAAGGAAACTATTTTTTACTGAGAGTGGCTGATAACGGTAAAGGTATAGAT
TTGAGTATAGCCGATAGAATTTTTGAACCTTTTTTTACTACAAAACAAAAAGGAAAAAATCCTGGGTTAGGGCTTCCTAT
GGTTTTTGGTTTTGTAAAGAGGAGCGGCGGTAGGATCGGGTTTGAATCTCATTTGGATGTAGGTTCTGATTTTTATATAT
ATATTCCGATAGAAGATTTGAAATCAGATTCGCATTTTATAAATCTAGAATCTTCCAAAAAAACAATTTTTTATTTTTCA
AATGAAGGGGAATTCTCAAGTAGAACGTCTTATCTTTTTCAGGGATTAGGATATAGAGTTCTTTGTTTTAAGGATCTCAA
CGTTTTAGAATCCAATCTTTCTAAGATACAATCTGAAACTATATTAGTTTCGCAAACTTGGCAGGAAGATTTTTTTAGAT
GGAAAGAGATTGTAATGAAAGCGCAAGGTTCTGGTTTGAAAGTGAAGTTTTTTTATTTTTCTTCTTCGGTTGACTTGGAA
AATTCTACCTCAATTCCTTGGCCGATTTCTCGAAAATCTCTTGAGAATCATTTCGGTATATTATAA

Upstream 100 bases:

>100_bases
ATGTTTAAAACTTACGACTTAGGAGCTAATTCCTTTATTCGAAAACCGGTCGAATTTGAAGCTTTTTTAGAAACGATTCG
AGCCCTCGGAAAATACTGGC

Downstream 100 bases:

>100_bases
TTTAGCCATTCATGAATCAGACCACATTACCCAATCTACTGATTCTGGACGACGAGGAAGAAATTGCAGGTATTCTCGGC
GATCTGGCTAGACAATGTGG

Product: histidine kinase response regulator hybrid protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MKSWSFQLFSDEISVCLIEDDDEDAILFREYLEEIPFPKYKVTRFKDFPSLFVDIEKNPSKYTIYVVDHFLGLQTGFEIL
NEIRKVVGSVSAVLISGISKEEIERITSEGGFQGYLEKKNLSAFTLAKTFFEVLKEKEDLRSETDIFLLKMEIISQFSGG
VAHDFNNILNIIVANLDILEMKCKDQPEVLNRIQSAQNAVLRGAEVNKKLLNFSRKQSLHPEIINPNLFIADFLEKSKNI
FSENVQLVFNPGSQEVFCKVDQTEFANCIMNLLQNANEASGGKILIETDTIVLNSKNKSLGLKEGNYFLLRVADNGKGID
LSIADRIFEPFFTTKQKGKNPGLGLPMVFGFVKRSGGRIGFESHLDVGSDFYIYIPIEDLKSDSHFINLESSKKTIFYFS
NEGEFSSRTSYLFQGLGYRVLCFKDLNVLESNLSKIQSETILVSQTWQEDFFRWKEIVMKAQGSGLKVKFFYFSSSVDLE
NSTSIPWPISRKSLENHFGIL

Sequences:

>Translated_501_residues
MKSWSFQLFSDEISVCLIEDDDEDAILFREYLEEIPFPKYKVTRFKDFPSLFVDIEKNPSKYTIYVVDHFLGLQTGFEIL
NEIRKVVGSVSAVLISGISKEEIERITSEGGFQGYLEKKNLSAFTLAKTFFEVLKEKEDLRSETDIFLLKMEIISQFSGG
VAHDFNNILNIIVANLDILEMKCKDQPEVLNRIQSAQNAVLRGAEVNKKLLNFSRKQSLHPEIINPNLFIADFLEKSKNI
FSENVQLVFNPGSQEVFCKVDQTEFANCIMNLLQNANEASGGKILIETDTIVLNSKNKSLGLKEGNYFLLRVADNGKGID
LSIADRIFEPFFTTKQKGKNPGLGLPMVFGFVKRSGGRIGFESHLDVGSDFYIYIPIEDLKSDSHFINLESSKKTIFYFS
NEGEFSSRTSYLFQGLGYRVLCFKDLNVLESNLSKIQSETILVSQTWQEDFFRWKEIVMKAQGSGLKVKFFYFSSSVDLE
NSTSIPWPISRKSLENHFGIL
>Mature_501_residues
MKSWSFQLFSDEISVCLIEDDDEDAILFREYLEEIPFPKYKVTRFKDFPSLFVDIEKNPSKYTIYVVDHFLGLQTGFEIL
NEIRKVVGSVSAVLISGISKEEIERITSEGGFQGYLEKKNLSAFTLAKTFFEVLKEKEDLRSETDIFLLKMEIISQFSGG
VAHDFNNILNIIVANLDILEMKCKDQPEVLNRIQSAQNAVLRGAEVNKKLLNFSRKQSLHPEIINPNLFIADFLEKSKNI
FSENVQLVFNPGSQEVFCKVDQTEFANCIMNLLQNANEASGGKILIETDTIVLNSKNKSLGLKEGNYFLLRVADNGKGID
LSIADRIFEPFFTTKQKGKNPGLGLPMVFGFVKRSGGRIGFESHLDVGSDFYIYIPIEDLKSDSHFINLESSKKTIFYFS
NEGEFSSRTSYLFQGLGYRVLCFKDLNVLESNLSKIQSETILVSQTWQEDFFRWKEIVMKAQGSGLKVKFFYFSSSVDLE
NSTSIPWPISRKSLENHFGIL

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=26.8085106382979, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786837, Length=140, Percent_Identity=35.7142857142857, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=235, Percent_Identity=24.6808510638298, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57077; Mature: 57077

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSWSFQLFSDEISVCLIEDDDEDAILFREYLEEIPFPKYKVTRFKDFPSLFVDIEKNPS
CCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCC
KYTIYVVDHFLGLQTGFEILNEIRKVVGSVSAVLISGISKEEIERITSEGGFQGYLEKKN
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCC
LSAFTLAKTFFEVLKEKEDLRSETDIFLLKMEIISQFSGGVAHDFNNILNIIVANLDILE
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHCCEEEE
MKCKDQPEVLNRIQSAQNAVLRGAEVNKKLLNFSRKQSLHPEIINPNLFIADFLEKSKNI
ECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHH
FSENVQLVFNPGSQEVFCKVDQTEFANCIMNLLQNANEASGGKILIETDTIVLNSKNKSL
HCCCCEEEECCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCCC
GLKEGNYFLLRVADNGKGIDLSIADRIFEPFFTTKQKGKNPGLGLPMVFGFVKRSGGRIG
CCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCC
FESHLDVGSDFYIYIPIEDLKSDSHFINLESSKKTIFYFSNEGEFSSRTSYLFQGLGYRV
CCCCCCCCCCEEEEEEHHHCCCCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHCCCEEE
LCFKDLNVLESNLSKIQSETILVSQTWQEDFFRWKEIVMKAQGSGLKVKFFYFSSSVDLE
EEEECHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
NSTSIPWPISRKSLENHFGIL
CCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MKSWSFQLFSDEISVCLIEDDDEDAILFREYLEEIPFPKYKVTRFKDFPSLFVDIEKNPS
CCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCC
KYTIYVVDHFLGLQTGFEILNEIRKVVGSVSAVLISGISKEEIERITSEGGFQGYLEKKN
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCC
LSAFTLAKTFFEVLKEKEDLRSETDIFLLKMEIISQFSGGVAHDFNNILNIIVANLDILE
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHCCEEEE
MKCKDQPEVLNRIQSAQNAVLRGAEVNKKLLNFSRKQSLHPEIINPNLFIADFLEKSKNI
ECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHH
FSENVQLVFNPGSQEVFCKVDQTEFANCIMNLLQNANEASGGKILIETDTIVLNSKNKSL
HCCCCEEEECCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCCC
GLKEGNYFLLRVADNGKGIDLSIADRIFEPFFTTKQKGKNPGLGLPMVFGFVKRSGGRIG
CCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCC
FESHLDVGSDFYIYIPIEDLKSDSHFINLESSKKTIFYFSNEGEFSSRTSYLFQGLGYRV
CCCCCCCCCCEEEEEEHHHCCCCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHCCCEEE
LCFKDLNVLESNLSKIQSETILVSQTWQEDFFRWKEIVMKAQGSGLKVKFFYFSSSVDLE
EEEECHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
NSTSIPWPISRKSLENHFGIL
CCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA