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The map label for this gene is ruvA

Identifier: 45657032

GI number: 45657032

Start: 1416118

End: 1416756

Strand: Direct

Name: ruvA

Synonym: LIC11148

Alternate gene names: 45657032

Gene position: 1416118-1416756 (Clockwise)

Preceding gene: 45657031

Following gene: 45657033

Centisome position: 33.11

GC content: 31.92

Gene sequence:

>639_bases
ATGATCTCAGGTTTAAAAGGAATTCTCAGAAAATTAGAAGTAGGATTTGTACATATAGAAACCGGTGGAATCACTTATGA
AGTGACGATTTCTTTTAAAACCTATTTAGAATTAAAAAATCTTCCTTTATTGAAGGAAGTTCAATTACAAATTTTTCACT
CTATAAATGAAAGAGGACAAAAATTATTTGGTTTTTTGACAGAACAAGACAAAGAGTTTTTCAAAGTTATGAAAGGTCTT
CAAGGAATAGGAGAATTGACCGCACTCAAAATTTTATCCTTTTTTTCGGCGGAAGATTTGTATCGGATCGTTCAATCTGG
AGAAGTCAAAGAACTGGAAAAAATTCCAAAGGTTAAAGGTAAAACTTCGGAAAAAATTTTTTTTGAGGTAAAACAAAATC
TTAAAAAACTGGAATTATTCTTGTCCGGCTCTTCGAAAGAGTCTTCGGTAATTTTAACTTCTTTGCTTCAGTCCCCAGAA
GAAATGGCATTTTCCAAGAAGAGAGAAACAGTGATCCTTGGTTTAGTTCAATTAGGATTTGAAGAAAAAACAGCCTCTAA
AGAGGTGGATAAGGTTTTAAAAATTTTTTCGTCAAATGACCCTGGAGAAATCATCCGTGAAATTTTAAAAAGTCTTTGA

Upstream 100 bases:

>100_bases
GTTAAGAGATTTGTTTTATTTGAACTTATTCGATACAATCGAATGTTCGTAGATTAAAAATTTATCTTTACTCTATTGAT
ATGGAGCGCTAAGTGGATTT

Downstream 100 bases:

>100_bases
GAGTTTTAGTTTTTATTTGATTAGAAAAAAAGTATATATTAAAGTATTAATTTAATCAAAATTTCTTTTTTGTATCGAAT
GGAAATCTTTTAAAAAAGGT

Product: DNA helicase subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MISGLKGILRKLEVGFVHIETGGITYEVTISFKTYLELKNLPLLKEVQLQIFHSINERGQKLFGFLTEQDKEFFKVMKGL
QGIGELTALKILSFFSAEDLYRIVQSGEVKELEKIPKVKGKTSEKIFFEVKQNLKKLELFLSGSSKESSVILTSLLQSPE
EMAFSKKRETVILGLVQLGFEEKTASKEVDKVLKIFSSNDPGEIIREILKSL

Sequences:

>Translated_212_residues
MISGLKGILRKLEVGFVHIETGGITYEVTISFKTYLELKNLPLLKEVQLQIFHSINERGQKLFGFLTEQDKEFFKVMKGL
QGIGELTALKILSFFSAEDLYRIVQSGEVKELEKIPKVKGKTSEKIFFEVKQNLKKLELFLSGSSKESSVILTSLLQSPE
EMAFSKKRETVILGLVQLGFEEKTASKEVDKVLKIFSSNDPGEIIREILKSL
>Mature_212_residues
MISGLKGILRKLEVGFVHIETGGITYEVTISFKTYLELKNLPLLKEVQLQIFHSINERGQKLFGFLTEQDKEFFKVMKGL
QGIGELTALKILSFFSAEDLYRIVQSGEVKELEKIPKVKGKTSEKIFFEVKQNLKKLELFLSGSSKESSVILTSLLQSPE
EMAFSKKRETVILGLVQLGFEEKTASKEVDKVLKIFSSNDPGEIIREILKSL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=214, Percent_Identity=31.3084112149533, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_LEPIC (Q72T73)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_001118.1
- HSSP:   P0A809
- ProteinModelPortal:   Q72T73
- SMR:   Q72T73
- GeneID:   2771326
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC11148
- NMPDR:   fig|267671.1.peg.1118
- HOGENOM:   HBG529249
- OMA:   MRIYHES
- ProtClustDB:   CLSK574640
- BioCyc:   LINT267671:LIC_11148-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 23994; Mature: 23994

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGLKGILRKLEVGFVHIETGGITYEVTISFKTYLELKNLPLLKEVQLQIFHSINERGQ
CCCHHHHHHHHHHHCEEEEEECCEEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KLFGFLTEQDKEFFKVMKGLQGIGELTALKILSFFSAEDLYRIVQSGEVKELEKIPKVKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
KTSEKIFFEVKQNLKKLELFLSGSSKESSVILTSLLQSPEEMAFSKKRETVILGLVQLGF
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
EEKTASKEVDKVLKIFSSNDPGEIIREILKSL
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MISGLKGILRKLEVGFVHIETGGITYEVTISFKTYLELKNLPLLKEVQLQIFHSINERGQ
CCCHHHHHHHHHHHCEEEEEECCEEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KLFGFLTEQDKEFFKVMKGLQGIGELTALKILSFFSAEDLYRIVQSGEVKELEKIPKVKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
KTSEKIFFEVKQNLKKLELFLSGSSKESSVILTSLLQSPEEMAFSKKRETVILGLVQLGF
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
EEKTASKEVDKVLKIFSSNDPGEIIREILKSL
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA