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The map label for this gene is cyaA [H]

Identifier: 45656792

GI number: 45656792

Start: 1086791

End: 1087210

Strand: Direct

Name: cyaA [H]

Synonym: LIC10901

Alternate gene names: 45656792

Gene position: 1086791-1087210 (Clockwise)

Preceding gene: 45656791

Following gene: 45656793

Centisome position: 25.41

GC content: 35.0

Gene sequence:

>420_bases
TTGGCCGCGTTGGATATGCGTAAGAGTTTGATACAATTCAACAAAGGAAGAGGGAGTGATAAAAAACCAAAAATATTTAT
CGGGATTGGAATCAATACGGGAGAAGTCATTGCGGGTCAAATCGGTTCGGAAGATAGGCTGGAATATACGGTCATAGGTG
ATACTGTCAATCTTGCTTCTAGAGTGGAATCTTTGACAAAAGTATTCGGTGCGGATATATTAATCACAGGAAATTCCTAC
GAAAAAGTAAAAGGAATTTTTAATGTAGAAAAACTAAAACCAATTCAAGTAAAAGGAAAAAAATCTCTACAGACTATCTA
TGCGGTTTTAGGGCATTCTAAAGATAAAAATTGTCCTAAAAATTTGAAGGAGCTTAGAAAACAAATTGGAATGGAATTCA
AATCTGGCAGGTCTAAATAA

Upstream 100 bases:

>100_bases
AACGAAAACGGAGGAAGCGTCAATAAATATATAGGAGACGCTATTATGGCCGTTTGGGGGGGAATTGGGACATACGAATT
CCGACACGGAAAGATCGATT

Downstream 100 bases:

>100_bases
CGGGTATGAAAGATAAAATTCTTTCAGGTGATAAACCGATTTTATTTCTTCTTATATTTAATATCGTATTGTTTACGGGA
GTATTTATATACGATTATAC

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MAALDMRKSLIQFNKGRGSDKKPKIFIGIGINTGEVIAGQIGSEDRLEYTVIGDTVNLASRVESLTKVFGADILITGNSY
EKVKGIFNVEKLKPIQVKGKKSLQTIYAVLGHSKDKNCPKNLKELRKQIGMEFKSGRSK

Sequences:

>Translated_139_residues
MAALDMRKSLIQFNKGRGSDKKPKIFIGIGINTGEVIAGQIGSEDRLEYTVIGDTVNLASRVESLTKVFGADILITGNSY
EKVKGIFNVEKLKPIQVKGKKSLQTIYAVLGHSKDKNCPKNLKELRKQIGMEFKSGRSK
>Mature_138_residues
AALDMRKSLIQFNKGRGSDKKPKIFIGIGINTGEVIAGQIGSEDRLEYTVIGDTVNLASRVESLTKVFGADILITGNSYE
KVKGIFNVEKLKPIQVKGKKSLQTIYAVLGHSKDKNCPKNLKELRKQIGMEFKSGRSK

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 15313; Mature: 15182

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALDMRKSLIQFNKGRGSDKKPKIFIGIGINTGEVIAGQIGSEDRLEYTVIGDTVNLAS
CCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCEEEEEECCHHHHHH
RVESLTKVFGADILITGNSYEKVKGIFNVEKLKPIQVKGKKSLQTIYAVLGHSKDKNCPK
HHHHHHHHHCCEEEEECCCHHHHHHHHCHHHCCCEEECCHHHHHHHHHHHCCCCCCCCHH
NLKELRKQIGMEFKSGRSK
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AALDMRKSLIQFNKGRGSDKKPKIFIGIGINTGEVIAGQIGSEDRLEYTVIGDTVNLAS
CCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEECCCCCCCCEEEEEECCHHHHHH
RVESLTKVFGADILITGNSYEKVKGIFNVEKLKPIQVKGKKSLQTIYAVLGHSKDKNCPK
HHHHHHHHHCCEEEEECCCHHHHHHHHCHHHCCCEEECCHHHHHHHHHHHCCCCCCCCHH
NLKELRKQIGMEFKSGRSK
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]