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The map label for this gene is trpB1

Identifier: 45656750

GI number: 45656750

Start: 1035553

End: 1036746

Strand: Direct

Name: trpB1

Synonym: LIC10859

Alternate gene names: 45656750

Gene position: 1035553-1036746 (Clockwise)

Preceding gene: 45656749

Following gene: 45656751

Centisome position: 24.21

GC content: 42.38

Gene sequence:

>1194_bases
ATGGGAAAGGAAAATCAACAAGGCTACTTTGGAGAATTTGGCGGTCGTTATTCTCCTGAAATTCTTCACGATGCTCTCGT
AGAACTTGAAACGACTTATAAAAAGCTCAAGAAAAACAAACACTTTAAAAAAGAACTAGAATACTATCGTAAAAATTATA
TCGGTCGTCCTTCTCCTCTTACTTATGCGGAACGTCTTTCTAAGGTTTGGGGCGGCGCTAAAATCTGGCTCAAACGCGAA
GATTTAAATCATACTGGAGCGCATAAGATCAATAATACGATCGGTCAGGTTTTGATTGCTAAGGCTATGGGTAAAACTAG
AATCATTGCGGAAACCGGCGCCGGTCAACACGGTGTTGCAACTGCAACCGTAGGCGCTATGTTCCAGATGGAAACCGTAG
TTTATATGGGTGAAGAAGACTTAAGACGTCAGGAACTCAATGCGATCCGGATGAGAATGTTGGGCGCTAAAGTCGTAGGT
GTTTCCAGTGGTACCGCTACTCTCAAAGACGCGACTAGCGAAGCGATGAGAGACTGGGCATTAAATGTTTCTAATACTCA
TTATATTGTGGGTTCTTCTATCGGTCCACATCCGTTTCCTACGATTGTCAGAGACTTCCAATCTGTGATCGGTATTGAAT
CTAGAAAACAGTTTAAAAAAGTAAACGATAAACTTCCAAACGCCGTGATTGCTTGTGTCGGCGGCGGCTCGAACGCGATC
GGTATGTTTTACGGTTTTATTCAGGATAAAAAAGTTAAACTCTTTGGTGTAGAAGCCGGTGGTTATTCTTCCGATCCTGG
TTCTCATTCTGCTACCATTCAATTTGGTAGAACCGGTTTTTTACACGGTACTAAAACTTTAGTGATTCAAGACGATTTTG
GACAGATCGTTCCCGCTCATTCCGTTTCTGCTGGATTGGATTATCCTGGTGTTGGTCCGGAACACGCTTACTTTCACAAA
AGTGGTAGAGTTGAATACGTTAACGTAGACGACGAGGGAGCGTTAGACGCGTTTATTGAAGTTTGTAGAATTGAAGGTAT
TATTCCCGCTTTGGAAACTGCGCATGCGTTCCGTTATGCGAAAGATCTGGCAAGAACTATGAGCAAAAAAGAGAATATTC
TGATTTGTCTTTCCGGTAGAGGTGACAAGGACGTGGCAGAGGTTTCTAGACTTAGAAAAGGAGAATTTATTTGA

Upstream 100 bases:

>100_bases
AGAAGGATCAAGAAGATTCCTTTGTTTTTTCCGGTTTTGATGATTTGGTCGCAAGAGTAGAATCTATGCGCCAAGAACTC
TTTACGGAATTGAGGTAGTT

Downstream 100 bases:

>100_bases
ACTCCATTTCTTCCGTTTTTTCTTCGGAGCAAAGTGTTTTTATTCCTTATATTTCTTTGGGTGATCCGGACTATGATTCC
TGCGTTATTTGGGCGGATGC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MGKENQQGYFGEFGGRYSPEILHDALVELETTYKKLKKNKHFKKELEYYRKNYIGRPSPLTYAERLSKVWGGAKIWLKRE
DLNHTGAHKINNTIGQVLIAKAMGKTRIIAETGAGQHGVATATVGAMFQMETVVYMGEEDLRRQELNAIRMRMLGAKVVG
VSSGTATLKDATSEAMRDWALNVSNTHYIVGSSIGPHPFPTIVRDFQSVIGIESRKQFKKVNDKLPNAVIACVGGGSNAI
GMFYGFIQDKKVKLFGVEAGGYSSDPGSHSATIQFGRTGFLHGTKTLVIQDDFGQIVPAHSVSAGLDYPGVGPEHAYFHK
SGRVEYVNVDDEGALDAFIEVCRIEGIIPALETAHAFRYAKDLARTMSKKENILICLSGRGDKDVAEVSRLRKGEFI

Sequences:

>Translated_397_residues
MGKENQQGYFGEFGGRYSPEILHDALVELETTYKKLKKNKHFKKELEYYRKNYIGRPSPLTYAERLSKVWGGAKIWLKRE
DLNHTGAHKINNTIGQVLIAKAMGKTRIIAETGAGQHGVATATVGAMFQMETVVYMGEEDLRRQELNAIRMRMLGAKVVG
VSSGTATLKDATSEAMRDWALNVSNTHYIVGSSIGPHPFPTIVRDFQSVIGIESRKQFKKVNDKLPNAVIACVGGGSNAI
GMFYGFIQDKKVKLFGVEAGGYSSDPGSHSATIQFGRTGFLHGTKTLVIQDDFGQIVPAHSVSAGLDYPGVGPEHAYFHK
SGRVEYVNVDDEGALDAFIEVCRIEGIIPALETAHAFRYAKDLARTMSKKENILICLSGRGDKDVAEVSRLRKGEFI
>Mature_396_residues
GKENQQGYFGEFGGRYSPEILHDALVELETTYKKLKKNKHFKKELEYYRKNYIGRPSPLTYAERLSKVWGGAKIWLKRED
LNHTGAHKINNTIGQVLIAKAMGKTRIIAETGAGQHGVATATVGAMFQMETVVYMGEEDLRRQELNAIRMRMLGAKVVGV
SSGTATLKDATSEAMRDWALNVSNTHYIVGSSIGPHPFPTIVRDFQSVIGIESRKQFKKVNDKLPNAVIACVGGGSNAIG
MFYGFIQDKKVKLFGVEAGGYSSDPGSHSATIQFGRTGFLHGTKTLVIQDDFGQIVPAHSVSAGLDYPGVGPEHAYFHKS
GRVEYVNVDDEGALDAFIEVCRIEGIIPALETAHAFRYAKDLARTMSKKENILICLSGRGDKDVAEVSRLRKGEFI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=386, Percent_Identity=50, Blast_Score=398, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6321412, Length=383, Percent_Identity=56.6579634464752, Blast_Score=438, Evalue=1e-124,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43680; Mature: 43549

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKENQQGYFGEFGGRYSPEILHDALVELETTYKKLKKNKHFKKELEYYRKNYIGRPSPL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
TYAERLSKVWGGAKIWLKREDLNHTGAHKINNTIGQVLIAKAMGKTRIIAETGAGQHGVA
HHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCH
TATVGAMFQMETVVYMGEEDLRRQELNAIRMRMLGAKVVGVSSGTATLKDATSEAMRDWA
HHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHC
LNVSNTHYIVGSSIGPHPFPTIVRDFQSVIGIESRKQFKKVNDKLPNAVIACVGGGSNAI
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCCHH
GMFYGFIQDKKVKLFGVEAGGYSSDPGSHSATIQFGRTGFLHGTKTLVIQDDFGQIVPAH
HHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEECCEEEECCCEEEEEECCCCCCCCCC
SVSAGLDYPGVGPEHAYFHKSGRVEYVNVDDEGALDAFIEVCRIEGIIPALETAHAFRYA
CCCCCCCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
KDLARTMSKKENILICLSGRGDKDVAEVSRLRKGEFI
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
GKENQQGYFGEFGGRYSPEILHDALVELETTYKKLKKNKHFKKELEYYRKNYIGRPSPL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
TYAERLSKVWGGAKIWLKREDLNHTGAHKINNTIGQVLIAKAMGKTRIIAETGAGQHGVA
HHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCH
TATVGAMFQMETVVYMGEEDLRRQELNAIRMRMLGAKVVGVSSGTATLKDATSEAMRDWA
HHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHC
LNVSNTHYIVGSSIGPHPFPTIVRDFQSVIGIESRKQFKKVNDKLPNAVIACVGGGSNAI
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCCHH
GMFYGFIQDKKVKLFGVEAGGYSSDPGSHSATIQFGRTGFLHGTKTLVIQDDFGQIVPAH
HHHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEECCEEEECCCEEEEEECCCCCCCCCC
SVSAGLDYPGVGPEHAYFHKSGRVEYVNVDDEGALDAFIEVCRIEGIIPALETAHAFRYA
CCCCCCCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
KDLARTMSKKENILICLSGRGDKDVAEVSRLRKGEFI
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA