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The map label for this gene is yfhR [C]

Identifier: 45656366

GI number: 45656366

Start: 540177

End: 540950

Strand: Reverse

Name: yfhR [C]

Synonym: LIC10468

Alternate gene names: 45656366

Gene position: 540950-540177 (Counterclockwise)

Preceding gene: 45656367

Following gene: 45656365

Centisome position: 12.65

GC content: 35.66

Gene sequence:

>774_bases
ATGTATAAATTTCTTAAATATTCCTGCATCCTTTTTCTTCTATTAGAAGTTTTTGGTTGTTTTGTTTCTCGAAAACTGAT
TTTTATAGCTCAAGGAAAAGATACTCTTCCTTCTTATTCTGGTACTCTACTTCAAATTCAAAACGAAGATAGAATCGTTT
ATGCTTATTTTACCCGAAACAGCTCCCGACTTGCTGTTGTTTTTCACGGTCAACATGGAACCTTGCAGAGTATGTCTTAT
CTTGGAGCTAAACTTTCACAAATGGGTTTTTCCGTTCTATTGGTTGAATATCCTGGATATGGAAAAGCAAAACGTTACTC
CAGTTCTGAAAGCAATATTTATTCAGACGCCGATGCTGCCATAAATTTTGTGCAGAAGAATTTTTCTTTTTCGAAACAAA
ACACGATCGCGATCGGATACTCTCTTGGAACGGGGGTTGCTGTAGAAATGGCTCGAAAAAATTTAGTTTCCAAGATGATA
CTTTTCGCGCCTTATACATCGATTCCAGATGTTGCTTCTTATCGATACGTTCCCATACTTCCTCAAATCTTGATTTGGGA
TCGATTTAACTCAATATCAAAATCCAAAGATCTTATATTGCCCGTATTGATCATCCATGGCAAAAAAGACGTAGCCGTTC
CTTACTATATGGGAGAGACTTTGAATAAAAGTTTTTCCAATGCAAAACTCATAACTCTTTTTAATGCAAATCATTCTCTT
TTCGGATCTATAACCGAAACTCATTGGAAACTAATCCGAGATTTTATCCAATGA

Upstream 100 bases:

>100_bases
GATGGCCCGTACCCATTTTTGTATTTTCAGATTTTTAAATTTAGAAACGGTTTCTTAATCTTATATTTTATTTCTAATCA
TACTTAATAACAATTTCTTA

Downstream 100 bases:

>100_bases
TTATTTTGTGATTTCCCAAAAGGGTTTAATACTTTCTTGAAACCGATCCTAAATCTACAAAATGATTTACAACACTTTCA
AAACTTGTCAAATTTCTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MYKFLKYSCILFLLLEVFGCFVSRKLIFIAQGKDTLPSYSGTLLQIQNEDRIVYAYFTRNSSRLAVVFHGQHGTLQSMSY
LGAKLSQMGFSVLLVEYPGYGKAKRYSSSESNIYSDADAAINFVQKNFSFSKQNTIAIGYSLGTGVAVEMARKNLVSKMI
LFAPYTSIPDVASYRYVPILPQILIWDRFNSISKSKDLILPVLIIHGKKDVAVPYYMGETLNKSFSNAKLITLFNANHSL
FGSITETHWKLIRDFIQ

Sequences:

>Translated_257_residues
MYKFLKYSCILFLLLEVFGCFVSRKLIFIAQGKDTLPSYSGTLLQIQNEDRIVYAYFTRNSSRLAVVFHGQHGTLQSMSY
LGAKLSQMGFSVLLVEYPGYGKAKRYSSSESNIYSDADAAINFVQKNFSFSKQNTIAIGYSLGTGVAVEMARKNLVSKMI
LFAPYTSIPDVASYRYVPILPQILIWDRFNSISKSKDLILPVLIIHGKKDVAVPYYMGETLNKSFSNAKLITLFNANHSL
FGSITETHWKLIRDFIQ
>Mature_257_residues
MYKFLKYSCILFLLLEVFGCFVSRKLIFIAQGKDTLPSYSGTLLQIQNEDRIVYAYFTRNSSRLAVVFHGQHGTLQSMSY
LGAKLSQMGFSVLLVEYPGYGKAKRYSSSESNIYSDADAAINFVQKNFSFSKQNTIAIGYSLGTGVAVEMARKNLVSKMI
LFAPYTSIPDVASYRYVPILPQILIWDRFNSISKSKDLILPVLIIHGKKDVAVPYYMGETLNKSFSNAKLITLFNANHSL
FGSITETHWKLIRDFIQ

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI194306564, Length=170, Percent_Identity=31.7647058823529, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI194306562, Length=170, Percent_Identity=31.7647058823529, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI151301175, Length=161, Percent_Identity=32.2981366459627, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI71051602, Length=191, Percent_Identity=29.3193717277487, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI71051600, Length=191, Percent_Identity=29.3193717277487, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25143554, Length=168, Percent_Identity=32.1428571428571, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281362521, Length=167, Percent_Identity=29.940119760479, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362519, Length=167, Percent_Identity=29.940119760479, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571878, Length=167, Percent_Identity=29.940119760479, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 29050; Mature: 29050

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKFLKYSCILFLLLEVFGCFVSRKLIFIAQGKDTLPSYSGTLLQIQNEDRIVYAYFTRN
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEEECCCEEEEEEEECC
SSRLAVVFHGQHGTLQSMSYLGAKLSQMGFSVLLVEYPGYGKAKRYSSSESNIYSDADAA
CCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHH
INFVQKNFSFSKQNTIAIGYSLGTGVAVEMARKNLVSKMILFAPYTSIPDVASYRYVPIL
HHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
PQILIWDRFNSISKSKDLILPVLIIHGKKDVAVPYYMGETLNKSFSNAKLITLFNANHSL
HHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEEECCHHHCCCCCCCEEEEEEECCCCE
FGSITETHWKLIRDFIQ
ECCHHHHHHHHHHHHHC
>Mature Secondary Structure
MYKFLKYSCILFLLLEVFGCFVSRKLIFIAQGKDTLPSYSGTLLQIQNEDRIVYAYFTRN
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEEECCCEEEEEEEECC
SSRLAVVFHGQHGTLQSMSYLGAKLSQMGFSVLLVEYPGYGKAKRYSSSESNIYSDADAA
CCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHH
INFVQKNFSFSKQNTIAIGYSLGTGVAVEMARKNLVSKMILFAPYTSIPDVASYRYVPIL
HHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCC
PQILIWDRFNSISKSKDLILPVLIIHGKKDVAVPYYMGETLNKSFSNAKLITLFNANHSL
HHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEEECCHHHCCCCCCCEEEEEEECCCCE
FGSITETHWKLIRDFIQ
ECCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]