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The map label for this gene is suhB [H]

Identifier: 41410246

GI number: 41410246

Start: 4626329

End: 4627156

Strand: Reverse

Name: suhB [H]

Synonym: MAP4148c

Alternate gene names: 41410246

Gene position: 4627156-4626329 (Counterclockwise)

Preceding gene: 41410248

Following gene: 41410236

Centisome position: 95.8

GC content: 68.72

Gene sequence:

>828_bases
ATGAAGTCAATGCAAGAGCTTTTTGAAATAGCTTGGCAGGCAACGCAAATCGGTGCCACCACGTTGAAGAAAACGCAGCC
GAGCTCGGTGCAGCACAAGGGTGACCGCGACCTGGTATCCGATGTCGACCTGACCATCCAGCGTGACATCGCCAACTACC
TGTCCCAGACCACGCCGGACGTCGCGCTGCTGGCCGAGGAGTCCGACCACCAACCCGACATCGAAACCGCCGAGTGGCTC
TGGGTTCTCGACCCGGTGGACGGCACGTCGAATTTCGTGCACGGGCTGCCGCTGTGCGCGGTGTCGCTGGCCCTGCTGCA
CGCCGGCCGCACCGTGGTGGCCGTCACCCACGCTCCCCTGCTGGGCAAGACCTACCACGCGATCGAGTCCAAGGGCGCGT
TCGTCAACGGGGAACGGATCACCGCCAGCGCCACCGACAGCCTCAGCGGGGCGATCGTCTCGCTCGGCGACTACGCCGTC
GGCCACGATGCGGGCCGGCTCAACGCGCACCGGCTGGCGCTCACCGCCGAGCTGGTGCCCCGGGCGGAGCGGATCCGGAT
GATCGGCGCCGCGACGCTCGACCTGGCGTTCGTCGCCGAGGGTGCCCTGGACGCCTGCGTGATGATGTCCAACAAGCCGT
GGGACACCGCCGCGGGGACGCTGATCGCCCGCGAAGCCGGAGCGCGGCTGACCGACGCGCAGGGCAACCCGCACACTCAC
AAGTCCGCGTCGACCGTCGTCGCCGCGCCGGGCATCGCCGAGCAGCTGGCCACCGTGATCCGCAACACCGAGGTCCCCAG
CGACCGGTACGCGGCCGCCGTCGGCTGA

Upstream 100 bases:

>100_bases
CAGCACGACGCCGGGGTGCGCGAGACGCGAAATCGCCGAGCCCGTATGATCGAACAACGCCGAACGCACGCCACCACTGG
AAGCGAGGCAAGCCTCTCCC

Downstream 100 bases:

>100_bases
ACGCCCGCCGTCGGCTCAGCCGAGCATCTCGGCGATGGGCACGGCCGCGGCGATCTTGGCGCGGGTCTTCATGACCTTGC
CCGGCATGCCGCCACCGACC

Product: hypothetical protein

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKSMQELFEIAWQATQIGATTLKKTQPSSVQHKGDRDLVSDVDLTIQRDIANYLSQTTPDVALLAEESDHQPDIETAEWL
WVLDPVDGTSNFVHGLPLCAVSLALLHAGRTVVAVTHAPLLGKTYHAIESKGAFVNGERITASATDSLSGAIVSLGDYAV
GHDAGRLNAHRLALTAELVPRAERIRMIGAATLDLAFVAEGALDACVMMSNKPWDTAAGTLIAREAGARLTDAQGNPHTH
KSASTVVAAPGIAEQLATVIRNTEVPSDRYAAAVG

Sequences:

>Translated_275_residues
MKSMQELFEIAWQATQIGATTLKKTQPSSVQHKGDRDLVSDVDLTIQRDIANYLSQTTPDVALLAEESDHQPDIETAEWL
WVLDPVDGTSNFVHGLPLCAVSLALLHAGRTVVAVTHAPLLGKTYHAIESKGAFVNGERITASATDSLSGAIVSLGDYAV
GHDAGRLNAHRLALTAELVPRAERIRMIGAATLDLAFVAEGALDACVMMSNKPWDTAAGTLIAREAGARLTDAQGNPHTH
KSASTVVAAPGIAEQLATVIRNTEVPSDRYAAAVG
>Mature_275_residues
MKSMQELFEIAWQATQIGATTLKKTQPSSVQHKGDRDLVSDVDLTIQRDIANYLSQTTPDVALLAEESDHQPDIETAEWL
WVLDPVDGTSNFVHGLPLCAVSLALLHAGRTVVAVTHAPLLGKTYHAIESKGAFVNGERITASATDSLSGAIVSLGDYAV
GHDAGRLNAHRLALTAELVPRAERIRMIGAATLDLAFVAEGALDACVMMSNKPWDTAAGTLIAREAGARLTDAQGNPHTH
KSASTVVAAPGIAEQLATVIRNTEVPSDRYAAAVG

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=246, Percent_Identity=31.7073170731707, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI221625487, Length=237, Percent_Identity=29.1139240506329, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI5031789, Length=237, Percent_Identity=29.1139240506329, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI221625507, Length=112, Percent_Identity=32.1428571428571, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1788882, Length=263, Percent_Identity=30.4182509505703, Blast_Score=127, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI193202570, Length=243, Percent_Identity=29.2181069958848, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI193202572, Length=245, Percent_Identity=28.1632653061224, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320493, Length=200, Percent_Identity=30.5, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321836, Length=210, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21357329, Length=230, Percent_Identity=30, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24664922, Length=269, Percent_Identity=28.6245353159851, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24664926, Length=244, Percent_Identity=29.0983606557377, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21357303, Length=237, Percent_Identity=32.4894514767932, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24664918, Length=205, Percent_Identity=32.6829268292683, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI21357957, Length=220, Percent_Identity=30.4545454545455, Blast_Score=98, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29088; Mature: 29088

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSMQELFEIAWQATQIGATTLKKTQPSSVQHKGDRDLVSDVDLTIQRDIANYLSQTTPD
CCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCC
VALLAEESDHQPDIETAEWLWVLDPVDGTSNFVHGLPLCAVSLALLHAGRTVVAVTHAPL
EEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCH
LGKTYHAIESKGAFVNGERITASATDSLSGAIVSLGDYAVGHDAGRLNAHRLALTAELVP
HCHHHHHHHCCCCEECCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCHHHEEEEHHHHC
RAERIRMIGAATLDLAFVAEGALDACVMMSNKPWDTAAGTLIAREAGARLTDAQGNPHTH
CHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCCCCC
KSASTVVAAPGIAEQLATVIRNTEVPSDRYAAAVG
CCCCEEEECCCHHHHHHHHHHCCCCCCHHHHCCCC
>Mature Secondary Structure
MKSMQELFEIAWQATQIGATTLKKTQPSSVQHKGDRDLVSDVDLTIQRDIANYLSQTTPD
CCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCC
VALLAEESDHQPDIETAEWLWVLDPVDGTSNFVHGLPLCAVSLALLHAGRTVVAVTHAPL
EEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCH
LGKTYHAIESKGAFVNGERITASATDSLSGAIVSLGDYAVGHDAGRLNAHRLALTAELVP
HCHHHHHHHCCCCEECCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCHHHEEEEHHHHC
RAERIRMIGAATLDLAFVAEGALDACVMMSNKPWDTAAGTLIAREAGARLTDAQGNPHTH
CHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCCCCC
KSASTVVAAPGIAEQLATVIRNTEVPSDRYAAAVG
CCCCEEEECCCHHHHHHHHHHCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]