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The map label for this gene is caiA [C]

Identifier: 41408449

GI number: 41408449

Start: 2642259

End: 2643386

Strand: Direct

Name: caiA [C]

Synonym: MAP2351

Alternate gene names: 41408449

Gene position: 2642259-2643386 (Clockwise)

Preceding gene: 41408448

Following gene: 41408450

Centisome position: 54.71

GC content: 69.86

Gene sequence:

>1128_bases
GTGACGAGCGGGGTAAGCACTCGATCCGAGGTGGTCGCCGAGTTCGCGGCCTGGCTGGCGGCGTTCCTGCCGAATGACTA
TTACGAGAACTACCGGCGGTACCGCTGGGACCTCACGCTGCGCCGCGATTATCAGCGGGCTGCGTTCGAGGCCGGGTGGA
TCCAGCCGACCTGGCCGCGCGAGCACGGCGGCCGGTCGCTGGGCCTGCGCGACGCGATGGAGGTCCGGCTGGAGGCGGCC
CTGCGCTCGGCGCCCAAGCTGCCCAACATCGCCGGCCCCAACGTCGCCGCCCCCGGCATCCGCCAGTTCGGCACGCCCGC
CCAGATCGAGCGGCTGCTGATGCCGCTGCTGCGCGGTGACGAGTGGTGGGCGCTGGGCATGTCCGAACCGGAAGCCGGCT
CGGACTTCGCCGGTCTGCGCACCCGCGCCGTGCGGGACGGCGACGTGTTCCGGGTCAACGGCCACAAGATCTGGACCACC
CAGGCTCACGAGTCGCGCTGGTGCACGCTGTATGCCCGCACCGATCCCGAGGCGCCCAAGCACCGCGGCATCTCCTGCCT
CATCCTGGATCTGCATTCGCCCGGGGTGCGGATCGAACCCATCCGGATGGCGTCGATCTCCGACGAAACATTCTGCGAGG
TGTTCCTCGACGACGTCGAGGTGCCGGCGGAAAACCTGTTGGGGCCGCTGCACGGCGGCTGGGACGTCGCGCTGTCGTCG
CTGCACCACGAACGCCAGATGATCTGGATCATGAACTGGGTCGAGATCAACCGCGGACTCGACGCGGTGCGAACCGCCAA
CGGCGCGGGGCCGGGCCACGACATCCACACCGAGCTCGGTTCCCTGCTGGCCGACGCCGAAGCCCTGCGCGCCACCGGGT
ATCGGGCCCTGGCCAACGAACTCGCGGGCCGGCCCAGCCCCGAAGCCGACACCATGAAGCTGCTGGGATCGCTTACCCTG
CAGCGTGTTTGGGAACTCGCGGCGGCCGCCGCGGGCCCCGATTCGGCCACCGACCCCGATCTGCTGTTCGAACGTCAGGA
CGCGCTGGCCGCGACCATCTACGGCGGAACGTCGGAGGTGCAGCGCAACATCATCGCCGAGCGGCTGCTCGGGCTGCCGA
AGGGATGA

Upstream 100 bases:

>100_bases
CGCATCTCTATGTCCGGCATGCCTGGCAGACCGCCGCCCTGCTGGGCGACAGCCGCGCGCTCTACCACGAGGTGGGCCGC
CGGTTCTGCGGAGGCGCGGC

Downstream 100 bases:

>100_bases
CGACCATGGACTACGACCTCGGCGACGACGCCGCCCAACTGCGAAGCCACCTGCGCGAGCTGGTCGCCAACCACATTCCC
GCCGACTTCCTGGGCGCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTSGVSTRSEVVAEFAAWLAAFLPNDYYENYRRYRWDLTLRRDYQRAAFEAGWIQPTWPREHGGRSLGLRDAMEVRLEAA
LRSAPKLPNIAGPNVAAPGIRQFGTPAQIERLLMPLLRGDEWWALGMSEPEAGSDFAGLRTRAVRDGDVFRVNGHKIWTT
QAHESRWCTLYARTDPEAPKHRGISCLILDLHSPGVRIEPIRMASISDETFCEVFLDDVEVPAENLLGPLHGGWDVALSS
LHHERQMIWIMNWVEINRGLDAVRTANGAGPGHDIHTELGSLLADAEALRATGYRALANELAGRPSPEADTMKLLGSLTL
QRVWELAAAAAGPDSATDPDLLFERQDALAATIYGGTSEVQRNIIAERLLGLPKG

Sequences:

>Translated_375_residues
MTSGVSTRSEVVAEFAAWLAAFLPNDYYENYRRYRWDLTLRRDYQRAAFEAGWIQPTWPREHGGRSLGLRDAMEVRLEAA
LRSAPKLPNIAGPNVAAPGIRQFGTPAQIERLLMPLLRGDEWWALGMSEPEAGSDFAGLRTRAVRDGDVFRVNGHKIWTT
QAHESRWCTLYARTDPEAPKHRGISCLILDLHSPGVRIEPIRMASISDETFCEVFLDDVEVPAENLLGPLHGGWDVALSS
LHHERQMIWIMNWVEINRGLDAVRTANGAGPGHDIHTELGSLLADAEALRATGYRALANELAGRPSPEADTMKLLGSLTL
QRVWELAAAAAGPDSATDPDLLFERQDALAATIYGGTSEVQRNIIAERLLGLPKG
>Mature_374_residues
TSGVSTRSEVVAEFAAWLAAFLPNDYYENYRRYRWDLTLRRDYQRAAFEAGWIQPTWPREHGGRSLGLRDAMEVRLEAAL
RSAPKLPNIAGPNVAAPGIRQFGTPAQIERLLMPLLRGDEWWALGMSEPEAGSDFAGLRTRAVRDGDVFRVNGHKIWTTQ
AHESRWCTLYARTDPEAPKHRGISCLILDLHSPGVRIEPIRMASISDETFCEVFLDDVEVPAENLLGPLHGGWDVALSSL
HHERQMIWIMNWVEINRGLDAVRTANGAGPGHDIHTELGSLLADAEALRATGYRALANELAGRPSPEADTMKLLGSLTLQ
RVWELAAAAAGPDSATDPDLLFERQDALAATIYGGTSEVQRNIIAERLLGLPKG

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=335, Percent_Identity=28.0597014925373, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI187960098, Length=335, Percent_Identity=28.0597014925373, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI226958414, Length=211, Percent_Identity=30.8056872037915, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI226958412, Length=210, Percent_Identity=30.952380952381, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4501859, Length=290, Percent_Identity=26.8965517241379, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI48976061, Length=215, Percent_Identity=32.5581395348837, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI211971008, Length=215, Percent_Identity=32.5581395348837, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI76496475, Length=160, Percent_Identity=33.75, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4557235, Length=160, Percent_Identity=33.75, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4557233, Length=282, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI21361497, Length=195, Percent_Identity=29.2307692307692, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4501857, Length=313, Percent_Identity=24.6006389776358, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI7656849, Length=204, Percent_Identity=26.9607843137255, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786223, Length=210, Percent_Identity=26.1904761904762, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081958, Length=237, Percent_Identity=26.5822784810127, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=344, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=383, Percent_Identity=26.3707571801567, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=202, Percent_Identity=28.7128712871287, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=341, Percent_Identity=26.6862170087977, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=343, Percent_Identity=26.8221574344023, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=265, Percent_Identity=27.1698113207547, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=338, Percent_Identity=27.810650887574, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=199, Percent_Identity=26.1306532663317, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=169, Percent_Identity=27.810650887574, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=205, Percent_Identity=27.3170731707317, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=161, Percent_Identity=31.055900621118, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=161, Percent_Identity=31.055900621118, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=155, Percent_Identity=31.6129032258064, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=230, Percent_Identity=25.2173913043478, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24646207, Length=335, Percent_Identity=28.6567164179104, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21355753, Length=160, Percent_Identity=32.5, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI281363737, Length=209, Percent_Identity=30.622009569378, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21356377, Length=366, Percent_Identity=26.5027322404372, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666513, Length=278, Percent_Identity=26.978417266187, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24660351, Length=222, Percent_Identity=26.5765765765766, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41473; Mature: 41342

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGVSTRSEVVAEFAAWLAAFLPNDYYENYRRYRWDLTLRRDYQRAAFEAGWIQPTWPR
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEEEHHHHHHHHHHHCCCCCCCCCH
EHGGRSLGLRDAMEVRLEAALRSAPKLPNIAGPNVAAPGIRQFGTPAQIERLLMPLLRGD
HCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCC
EWWALGMSEPEAGSDFAGLRTRAVRDGDVFRVNGHKIWTTQAHESRWCTLYARTDPEAPK
CEEEECCCCCCCCCCHHHHHHHEECCCCEEEECCEEEEEECCCCCCEEEEEECCCCCCCC
HRGISCLILDLHSPGVRIEPIRMASISDETFCEVFLDDVEVPAENLLGPLHGGWDVALSS
CCCCEEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHH
LHHERQMIWIMNWVEINRGLDAVRTANGAGPGHDIHTELGSLLADAEALRATGYRALANE
HHHHHHEEEEEHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGRPSPEADTMKLLGSLTLQRVWELAAAAAGPDSATDPDLLFERQDALAATIYGGTSEV
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCHHHH
QRNIIAERLLGLPKG
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSGVSTRSEVVAEFAAWLAAFLPNDYYENYRRYRWDLTLRRDYQRAAFEAGWIQPTWPR
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEEEHHHHHHHHHHHCCCCCCCCCH
EHGGRSLGLRDAMEVRLEAALRSAPKLPNIAGPNVAAPGIRQFGTPAQIERLLMPLLRGD
HCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCC
EWWALGMSEPEAGSDFAGLRTRAVRDGDVFRVNGHKIWTTQAHESRWCTLYARTDPEAPK
CEEEECCCCCCCCCCHHHHHHHEECCCCEEEECCEEEEEECCCCCCEEEEEECCCCCCCC
HRGISCLILDLHSPGVRIEPIRMASISDETFCEVFLDDVEVPAENLLGPLHGGWDVALSS
CCCCEEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHH
LHHERQMIWIMNWVEINRGLDAVRTANGAGPGHDIHTELGSLLADAEALRATGYRALANE
HHHHHHEEEEEHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGRPSPEADTMKLLGSLTLQRVWELAAAAAGPDSATDPDLLFERQDALAATIYGGTSEV
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCHHHH
QRNIIAERLLGLPKG
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]