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The map label for this gene is yngJ [H]

Identifier: 41408450

GI number: 41408450

Start: 2643392

End: 2644540

Strand: Direct

Name: yngJ [H]

Synonym: MAP2352

Alternate gene names: 41408450

Gene position: 2643392-2644540 (Clockwise)

Preceding gene: 41408449

Following gene: 41408451

Centisome position: 54.73

GC content: 70.23

Gene sequence:

>1149_bases
ATGGACTACGACCTCGGCGACGACGCCGCCCAACTGCGAAGCCACCTGCGCGAGCTGGTCGCCAACCACATTCCCGCCGA
CTTCCTGGGCGCCTGCACGGAGAACCCGCAGGACCTCGCCACCACCGAGACGTTCTGCAAACTGCTGGCCGCCGAGGGGC
TGCTGGCCCTTGCGTGGCCGAAAGAGCATGGCGGCGGCGGTGGTTCGGTCTGGCAGCAGACCGTGCTGCGCGAGGAGATG
TGGGCCCAGCACGAGCCGCGCGGCCCGCAGTACATGGGCATCAACTGGGTCGGGCCGGCCCTGATGCGCTACGGCACCGA
GGAGCAGAAGGCCAAGCACCTGGCGGCCATCGCCGCCGGCGACGTGATCTGGTGCCAGGGATTCTCCGAGCCGGAGGCCG
GCACCGATCTGGTGTCGTTGCGCACCCGCGCCGTTGCCGACGGTGACGGTTGGCGGATCACCGGCCAGAAGGTGTGGACG
TCGTACGCGCTGATGGCATCGTGGTGCGTGCTGGCGGCCTGCACCGACCCCGACGCGCCAAAACACAAGCGGCTCACGCT
CTTTCTGATACCGATGGACCGGCCCGGGTTCACCGTCCGGCCGATCCCGTCCATGCTGGGGCCGCATCACCTCAACGAGA
TGTTCCTCGACGACGTCCCGGCGTATCCCGGCGACGTACTGGGCGAGGTCGGCGACGGCTGGCGGGTGATGCGCGAGGCG
CTGGCCTACGAACGGGTGGGGATCGCGCGCTACGCGCGCTGCGAGTCACTGCTGGAGCGGATGCGCGGCCGGCTCGGTGA
CGAGTGGGAGCAACTGCCCGAATCGATCCGGGCCCGCTGGGTGCGCGCGCTCGTCGACCTGCGGGTCGCCCGGCTGCTGG
CCTATCGCGCCGTGTCGCTGCAGGACGACCCGGCCGCCGGCGCAGCGGCCAGCGCCGCCCGCATCGCCACCACCACGTGC
GATCAGCAGGTCGCCGAGCTGTTGTTCGACGTGCTGGGCCCGACCGCGCTGGATGCCGGGTCCGGCGCGCCGCTGCACGG
GGCCATCGAAGATCATTGGCGTTACGCACAGGCAGCCACCGTCGCATCGGGCACCATCGAGGTGCAGAAGATGTTGGTGG
CCCGAGACGTACTGGGAGGGCACCGGTGA

Upstream 100 bases:

>100_bases
GTCAGGACGCGCTGGCCGCGACCATCTACGGCGGAACGTCGGAGGTGCAGCGCAACATCATCGCCGAGCGGCTGCTCGGG
CTGCCGAAGGGATGACGACC

Downstream 100 bases:

>100_bases
AAACCGATCTGCCGCAAGATATCAGCGACTTCGCCACGGTCGCCGCCAAACGGTTCACCCGATTGGGCGGGCCGCCGGCG
GCGCTGCGCGCCGAGACCGA

Product: hypothetical protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MDYDLGDDAAQLRSHLRELVANHIPADFLGACTENPQDLATTETFCKLLAAEGLLALAWPKEHGGGGGSVWQQTVLREEM
WAQHEPRGPQYMGINWVGPALMRYGTEEQKAKHLAAIAAGDVIWCQGFSEPEAGTDLVSLRTRAVADGDGWRITGQKVWT
SYALMASWCVLAACTDPDAPKHKRLTLFLIPMDRPGFTVRPIPSMLGPHHLNEMFLDDVPAYPGDVLGEVGDGWRVMREA
LAYERVGIARYARCESLLERMRGRLGDEWEQLPESIRARWVRALVDLRVARLLAYRAVSLQDDPAAGAAASAARIATTTC
DQQVAELLFDVLGPTALDAGSGAPLHGAIEDHWRYAQAATVASGTIEVQKMLVARDVLGGHR

Sequences:

>Translated_382_residues
MDYDLGDDAAQLRSHLRELVANHIPADFLGACTENPQDLATTETFCKLLAAEGLLALAWPKEHGGGGGSVWQQTVLREEM
WAQHEPRGPQYMGINWVGPALMRYGTEEQKAKHLAAIAAGDVIWCQGFSEPEAGTDLVSLRTRAVADGDGWRITGQKVWT
SYALMASWCVLAACTDPDAPKHKRLTLFLIPMDRPGFTVRPIPSMLGPHHLNEMFLDDVPAYPGDVLGEVGDGWRVMREA
LAYERVGIARYARCESLLERMRGRLGDEWEQLPESIRARWVRALVDLRVARLLAYRAVSLQDDPAAGAAASAARIATTTC
DQQVAELLFDVLGPTALDAGSGAPLHGAIEDHWRYAQAATVASGTIEVQKMLVARDVLGGHR
>Mature_382_residues
MDYDLGDDAAQLRSHLRELVANHIPADFLGACTENPQDLATTETFCKLLAAEGLLALAWPKEHGGGGGSVWQQTVLREEM
WAQHEPRGPQYMGINWVGPALMRYGTEEQKAKHLAAIAAGDVIWCQGFSEPEAGTDLVSLRTRAVADGDGWRITGQKVWT
SYALMASWCVLAACTDPDAPKHKRLTLFLIPMDRPGFTVRPIPSMLGPHHLNEMFLDDVPAYPGDVLGEVGDGWRVMREA
LAYERVGIARYARCESLLERMRGRLGDEWEQLPESIRARWVRALVDLRVARLLAYRAVSLQDDPAAGAAASAARIATTTC
DQQVAELLFDVLGPTALDAGSGAPLHGAIEDHWRYAQAATVASGTIEVQKMLVARDVLGGHR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=350, Percent_Identity=28.8571428571429, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI226958412, Length=249, Percent_Identity=26.5060240963855, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4501859, Length=388, Percent_Identity=24.7422680412371, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI226958414, Length=211, Percent_Identity=28.9099526066351, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI4501857, Length=348, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI187960098, Length=346, Percent_Identity=25.1445086705202, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557231, Length=346, Percent_Identity=25.1445086705202, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI21361497, Length=209, Percent_Identity=31.1004784688995, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI211971008, Length=303, Percent_Identity=28.3828382838284, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI48976061, Length=303, Percent_Identity=28.3828382838284, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI76496475, Length=341, Percent_Identity=25.2199413489736, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4557235, Length=341, Percent_Identity=25.2199413489736, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1786223, Length=396, Percent_Identity=24.7474747474747, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081958, Length=398, Percent_Identity=24.1206030150754, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=342, Percent_Identity=27.1929824561404, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=346, Percent_Identity=26.3005780346821, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17538396, Length=205, Percent_Identity=31.219512195122, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=356, Percent_Identity=26.123595505618, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=401, Percent_Identity=26.1845386533666, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=392, Percent_Identity=23.2142857142857, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=198, Percent_Identity=31.8181818181818, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=200, Percent_Identity=28.5, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17505929, Length=229, Percent_Identity=25.764192139738, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=229, Percent_Identity=26.2008733624454, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646207, Length=343, Percent_Identity=29.7376093294461, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356377, Length=344, Percent_Identity=27.6162790697674, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24666513, Length=348, Percent_Identity=25.8620689655172, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21355753, Length=243, Percent_Identity=27.1604938271605, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281363737, Length=156, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24660351, Length=288, Percent_Identity=25.6944444444444, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41798; Mature: 41798

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYDLGDDAAQLRSHLRELVANHIPADFLGACTENPQDLATTETFCKLLAAEGLLALAWP
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEECC
KEHGGGGGSVWQQTVLREEMWAQHEPRGPQYMGINWVGPALMRYGTEEQKAKHLAAIAAG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHCCCHHHHHHHHHHHHHC
DVIWCQGFSEPEAGTDLVSLRTRAVADGDGWRITGQKVWTSYALMASWCVLAACTDPDAP
CEEEECCCCCCCCCCHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
KHKRLTLFLIPMDRPGFTVRPIPSMLGPHHLNEMFLDDVPAYPGDVLGEVGDGWRVMREA
CCCEEEEEEEECCCCCCEECCCHHHHCHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHH
LAYERVGIARYARCESLLERMRGRLGDEWEQLPESIRARWVRALVDLRVARLLAYRAVSL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QDDPAAGAAASAARIATTTCDQQVAELLFDVLGPTALDAGSGAPLHGAIEDHWRYAQAAT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VASGTIEVQKMLVARDVLGGHR
HHCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDYDLGDDAAQLRSHLRELVANHIPADFLGACTENPQDLATTETFCKLLAAEGLLALAWP
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEECC
KEHGGGGGSVWQQTVLREEMWAQHEPRGPQYMGINWVGPALMRYGTEEQKAKHLAAIAAG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHCCCHHHHHHHHHHHHHC
DVIWCQGFSEPEAGTDLVSLRTRAVADGDGWRITGQKVWTSYALMASWCVLAACTDPDAP
CEEEECCCCCCCCCCHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCC
KHKRLTLFLIPMDRPGFTVRPIPSMLGPHHLNEMFLDDVPAYPGDVLGEVGDGWRVMREA
CCCEEEEEEEECCCCCCEECCCHHHHCHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHH
LAYERVGIARYARCESLLERMRGRLGDEWEQLPESIRARWVRALVDLRVARLLAYRAVSL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QDDPAAGAAASAARIATTTCDQQVAELLFDVLGPTALDAGSGAPLHGAIEDHWRYAQAAT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VASGTIEVQKMLVARDVLGGHR
HHCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]