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The map label for this gene is argD

Identifier: 41407462

GI number: 41407462

Start: 1466722

End: 1467951

Strand: Direct

Name: argD

Synonym: MAP1364

Alternate gene names: 41407462

Gene position: 1466722-1467951 (Clockwise)

Preceding gene: 41407461

Following gene: 41407463

Centisome position: 30.37

GC content: 72.03

Gene sequence:

>1230_bases
ATGGTGACAAACACGGACGCGCTGCGGCGGCGCTGGGAGGCCGTGATGATGCACAACTACGGCACCCCGCCGGTCGCGCT
GGCCAGCGGCGAGGGCGCCGTGGTCACCGACGTCGACGGCAACACCTACCTCGATCTGCTCGGCGGCATCGCGGTCAACG
TGCTGGGCCATCGCCACCCGGCGATCATCGAGGCCGTCACGAAGCAGCTGTCGACGCTGGGCCACACCTCGAATCTGTAT
GCCACCGAGCCGAGTCTGGCGCTGGCCGAGGAACTGGTGGCCCTGCTGGGCGCCGGCCACGAACCAGCCGGCCACGAATC
CGGCGGCACCGAATCCGCGGGCACGGCGCGGGTGTTCTTCTGCAACTCCGGAACCGAGGCCAACGAGGTCGCGTTCAAGC
TGTCGAGGCTCACCGGCCGCACCAAACTCGTTGCGGCACAAGAGGCCTTCCACGGCCGGACCATGGGTTCGCTCGCGCTG
ACCGGTCAGCCCAGCAAGCAGGCGCCGTTCGCGCCGCTGCCCGGCGACGTCACGCACGTGCCCTACGGCGACGCCGAGGC
GCTGGCCGCCGCGGTCGACGACGGCACCGCGGCGGTGTTTTTGGAACCGATCATGGGGGAGAGCGGCGTCGTCGTCCCAC
CCGAGGGATACCTGGCCGCCGCCCGCGACATCACCGCACGGCACGGCGCGCTGCTGGTGCTCGACGAGGTGCAGACCGGA
ATGGGCTGCACCGGAACGTTTTTCGCCCATCAGCACGACGGCATCACCCCCGACGTGGTGACGCTGGCCAAGGGGCTCGG
CGGCGGCCTGCCGATCGGCGCCTGCCTGGCCGTCGGTCCGGCCGCCGACCTGCTGACCCCGGGCCTGCACGGCAGCACCT
TCGGCGGCAACCCGGTGTGCGCGGCCGCGGCGCTCGCGGTGTTGCGGGTGCTGGCTTCGGAGAACCTGGTCCGGCACGCC
GAGGTGCTGGGCAAGTCGCTGCACCAGGGCATCGAGGGACTCGGCCATCCGCTGGTCGACCACGTGCGCGGGCGCGGACT
GCTGTGCGGGGTGGTGCTGACCGCGCCGCACGCCAAGGACGCCGAGGCGGCCGCCCGCGAGGCCGGATTCCTGGTGAACG
CCGCCGCCCCCGGCGTCATCCGGCTGGCGCCGCCGCTGATCGTCACCGAGGCCCAGATCGACGGCTTCATCGCCGCGCTG
CCCGGCATTCTCGACAGGGCCGCGGCATGA

Upstream 100 bases:

>100_bases
TCGTGACGAAGGGTGCCTTGCCAGCCGCCGAGCGTCACGCCAGCGTGGCGTTGGGCGCCGAGAACCACCCCAGCGTGACG
CTCGGGAAGGGGGATCGGCG

Downstream 100 bases:

>100_bases
CCCCCCGGCATTTCCTGCGCGACGACGACCTGTCGCCGGCCGAGCAGGCCGAGGTGTTGGCGCTGGCCGCCGAGCTGAAG
AAGGACCCGTTCAGCGCGCG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MVTNTDALRRRWEAVMMHNYGTPPVALASGEGAVVTDVDGNTYLDLLGGIAVNVLGHRHPAIIEAVTKQLSTLGHTSNLY
ATEPSLALAEELVALLGAGHEPAGHESGGTESAGTARVFFCNSGTEANEVAFKLSRLTGRTKLVAAQEAFHGRTMGSLAL
TGQPSKQAPFAPLPGDVTHVPYGDAEALAAAVDDGTAAVFLEPIMGESGVVVPPEGYLAAARDITARHGALLVLDEVQTG
MGCTGTFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAADLLTPGLHGSTFGGNPVCAAAALAVLRVLASENLVRHA
EVLGKSLHQGIEGLGHPLVDHVRGRGLLCGVVLTAPHAKDAEAAAREAGFLVNAAAPGVIRLAPPLIVTEAQIDGFIAAL
PGILDRAAA

Sequences:

>Translated_409_residues
MVTNTDALRRRWEAVMMHNYGTPPVALASGEGAVVTDVDGNTYLDLLGGIAVNVLGHRHPAIIEAVTKQLSTLGHTSNLY
ATEPSLALAEELVALLGAGHEPAGHESGGTESAGTARVFFCNSGTEANEVAFKLSRLTGRTKLVAAQEAFHGRTMGSLAL
TGQPSKQAPFAPLPGDVTHVPYGDAEALAAAVDDGTAAVFLEPIMGESGVVVPPEGYLAAARDITARHGALLVLDEVQTG
MGCTGTFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAADLLTPGLHGSTFGGNPVCAAAALAVLRVLASENLVRHA
EVLGKSLHQGIEGLGHPLVDHVRGRGLLCGVVLTAPHAKDAEAAAREAGFLVNAAAPGVIRLAPPLIVTEAQIDGFIAAL
PGILDRAAA
>Mature_409_residues
MVTNTDALRRRWEAVMMHNYGTPPVALASGEGAVVTDVDGNTYLDLLGGIAVNVLGHRHPAIIEAVTKQLSTLGHTSNLY
ATEPSLALAEELVALLGAGHEPAGHESGGTESAGTARVFFCNSGTEANEVAFKLSRLTGRTKLVAAQEAFHGRTMGSLAL
TGQPSKQAPFAPLPGDVTHVPYGDAEALAAAVDDGTAAVFLEPIMGESGVVVPPEGYLAAARDITARHGALLVLDEVQTG
MGCTGTFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAADLLTPGLHGSTFGGNPVCAAAALAVLRVLASENLVRHA
EVLGKSLHQGIEGLGHPLVDHVRGRGLLCGVVLTAPHAKDAEAAAREAGFLVNAAAPGVIRLAPPLIVTEAQIDGFIAAL
PGILDRAAA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=405, Percent_Identity=35.5555555555556, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI284507298, Length=286, Percent_Identity=38.4615384615385, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI13994255, Length=452, Percent_Identity=28.9823008849558, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI24119277, Length=453, Percent_Identity=30.0220750551876, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI37574042, Length=435, Percent_Identity=25.7471264367816, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226442705, Length=435, Percent_Identity=24.8275862068966, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI226442709, Length=400, Percent_Identity=26.25, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI188536080, Length=429, Percent_Identity=26.1072261072261, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI38679950, Length=429, Percent_Identity=26.1072261072261, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI38679946, Length=429, Percent_Identity=26.1072261072261, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1788044, Length=417, Percent_Identity=39.568345323741, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI1789759, Length=416, Percent_Identity=39.4230769230769, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI145693181, Length=404, Percent_Identity=38.1188118811881, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789016, Length=438, Percent_Identity=32.1917808219178, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787560, Length=439, Percent_Identity=33.4851936218679, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1786349, Length=367, Percent_Identity=32.1525885558583, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786991, Length=435, Percent_Identity=27.5862068965517, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=389, Percent_Identity=34.7043701799486, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=429, Percent_Identity=30.0699300699301, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=255, Percent_Identity=36.4705882352941, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=457, Percent_Identity=28.8840262582057, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17541228, Length=421, Percent_Identity=24.9406175771971, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71981843, Length=176, Percent_Identity=30.6818181818182, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323470, Length=427, Percent_Identity=32.7868852459016, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6324432, Length=413, Percent_Identity=31.9612590799031, Blast_Score=200, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6321456, Length=444, Percent_Identity=25.4504504504505, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357415, Length=388, Percent_Identity=34.5360824742268, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28574759, Length=423, Percent_Identity=30.9692671394799, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI161085790, Length=426, Percent_Identity=30.2816901408451, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=29.8578199052133, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI281366494, Length=426, Percent_Identity=26.5258215962441, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24667139, Length=426, Percent_Identity=26.5258215962441, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24667143, Length=426, Percent_Identity=26.5258215962441, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41584; Mature: 41584

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTNTDALRRRWEAVMMHNYGTPPVALASGEGAVVTDVDGNTYLDLLGGIAVNVLGHRHP
CCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHCCCCH
AIIEAVTKQLSTLGHTSNLYATEPSLALAEELVALLGAGHEPAGHESGGTESAGTARVFF
HHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
CNSGTEANEVAFKLSRLTGRTKLVAAQEAFHGRTMGSLALTGQPSKQAPFAPLPGDVTHV
ECCCCCHHHHHHHHHHHCCCHHEEEHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCC
PYGDAEALAAAVDDGTAAVFLEPIMGESGVVVPPEGYLAAARDITARHGALLVLDEVQTG
CCCCHHHHHHHHCCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHCCCEEEEEECCCCC
MGCTGTFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAADLLTPGLHGSTFGGNPVC
CCCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHCCCHHHHHCCCCCCCCCCCCHHH
AAAALAVLRVLASENLVRHAEVLGKSLHQGIEGLGHPLVDHVRGRGLLCGVVLTAPHAKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEEECCCCCC
AEAAAREAGFLVNAAAPGVIRLAPPLIVTEAQIDGFIAALPGILDRAAA
HHHHHHHCCEEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVTNTDALRRRWEAVMMHNYGTPPVALASGEGAVVTDVDGNTYLDLLGGIAVNVLGHRHP
CCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHCCCCH
AIIEAVTKQLSTLGHTSNLYATEPSLALAEELVALLGAGHEPAGHESGGTESAGTARVFF
HHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
CNSGTEANEVAFKLSRLTGRTKLVAAQEAFHGRTMGSLALTGQPSKQAPFAPLPGDVTHV
ECCCCCHHHHHHHHHHHCCCHHEEEHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCC
PYGDAEALAAAVDDGTAAVFLEPIMGESGVVVPPEGYLAAARDITARHGALLVLDEVQTG
CCCCHHHHHHHHCCCCEEEEEEECCCCCCEEECCCCCCHHHHHHHHCCCEEEEEECCCCC
MGCTGTFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAADLLTPGLHGSTFGGNPVC
CCCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHCCCHHHHHCCCCCCCCCCCCHHH
AAAALAVLRVLASENLVRHAEVLGKSLHQGIEGLGHPLVDHVRGRGLLCGVVLTAPHAKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEEECCCCCC
AEAAAREAGFLVNAAAPGVIRLAPPLIVTEAQIDGFIAALPGILDRAAA
HHHHHHHCCEEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]