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The map label for this gene is argB

Identifier: 41407461

GI number: 41407461

Start: 1465740

End: 1466627

Strand: Direct

Name: argB

Synonym: MAP1363

Alternate gene names: 41407461

Gene position: 1465740-1466627 (Clockwise)

Preceding gene: 41407460

Following gene: 41407462

Centisome position: 30.35

GC content: 69.03

Gene sequence:

>888_bases
ATGACGCCCTCGACCGAAGCGCTGCCCACCGCGGTCAAGGCGCAGGTGCTGGCCGAAGCGCTGCCCTGGCTCAAGCAGCT
GCACGGCAAGATTGTGGTGATCAAGTACGGCGGCAACGCGATGACCGACGACACCCTGCGGCGCGCCTTCGCCGCCGACA
TGGCGTTCCTGCGCAACTGCGGCATCCACCCCGTCGTCGTGCACGGCGGCGGGCCGCAGATCACCGCGATGCTGCGCCGG
CTGGGCATCCCTGGCGACTTCAAGGGCGGATTCCGGGTCACCACACCGGAAGTGCTCGACGTGGCGCGGATGGTGCTGTT
CGGCCAGGTCGGCCGCGAACTGGTCAACCTGATCAACGCGCACGGCCCGTATGCGGTCGGCATCACCGGCGAGGACGCCC
AGCTGTTCACCGCCGTGCGGCGCAGCGTCACCGTGGACGGCGTGACCACCGACATCGGCCTGGTGGGCGACGTGGAGCGG
GTCAACGCCGCCGCGGTGCTGGATTTGATTGCGGCGCGGCGCATTCCGGTGGTGTCGACGCTGGCCCCGGACGCCGAAGG
GGTGGTGCACAACATCAACGCCGACACCGCGGCGGCGGCGCTGGCCGAAGCCCTGGGCGCCGAGAAGCTGCTGATGCTCA
CCGATGTCGAGGGCCTGTACACCAGCTGGCCCAACCGTGATTCGCTGGTCAGCGAGATCGACACGGCCACACTGTCCCAA
CTGCTACCCACGCTGGAGGCGGGCATGATCCCCAAGGTCGAGGCGTGTCTGCGGGCGGTGTCCGCGGGCGTGCCCAGCGC
GCACGTCATCGACGGGCGGGTCGAACACTGTGTGCTGGTGGAGCTTTTCACCGACGAGGGCACCGGCACCAAGGTGGTGA
GCTCGTGA

Upstream 100 bases:

>100_bases
TCGACATCACCGTCGACCTGCGGCTCGGCGACGGGCGGGCCACCGTCCGCACCACCGACCTGTCGCACGGCTACGTCGAA
GAGAATTCGGCCTACAGCTC

Downstream 100 bases:

>100_bases
CGAAGGGTGCCTTGCCAGCCGCCGAGCGTCACGCCAGCGTGGCGTTGGGCGCCGAGAACCACCCCAGCGTGACGCTCGGG
AAGGGGGATCGGCGATGGTG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTPSTEALPTAVKAQVLAEALPWLKQLHGKIVVIKYGGNAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRR
LGIPGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFTAVRRSVTVDGVTTDIGLVGDVER
VNAAAVLDLIAARRIPVVSTLAPDAEGVVHNINADTAAAALAEALGAEKLLMLTDVEGLYTSWPNRDSLVSEIDTATLSQ
LLPTLEAGMIPKVEACLRAVSAGVPSAHVIDGRVEHCVLVELFTDEGTGTKVVSS

Sequences:

>Translated_295_residues
MTPSTEALPTAVKAQVLAEALPWLKQLHGKIVVIKYGGNAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRR
LGIPGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFTAVRRSVTVDGVTTDIGLVGDVER
VNAAAVLDLIAARRIPVVSTLAPDAEGVVHNINADTAAAALAEALGAEKLLMLTDVEGLYTSWPNRDSLVSEIDTATLSQ
LLPTLEAGMIPKVEACLRAVSAGVPSAHVIDGRVEHCVLVELFTDEGTGTKVVSS
>Mature_294_residues
TPSTEALPTAVKAQVLAEALPWLKQLHGKIVVIKYGGNAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRL
GIPGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFTAVRRSVTVDGVTTDIGLVGDVERV
NAAAVLDLIAARRIPVVSTLAPDAEGVVHNINADTAAAALAEALGAEKLLMLTDVEGLYTSWPNRDSLVSEIDTATLSQL
LPTLEAGMIPKVEACLRAVSAGVPSAHVIDGRVEHCVLVELFTDEGTGTKVVSS

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI145693208, Length=231, Percent_Identity=32.034632034632, Blast_Score=75, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320913, Length=270, Percent_Identity=29.2592592592593, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 31013; Mature: 30882

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSTEALPTAVKAQVLAEALPWLKQLHGKIVVIKYGGNAMTDDTLRRAFAADMAFLRNC
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHC
GIHPVVVHGGGPQITAMLRRLGIPGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINA
CCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
HGPYAVGITGEDAQLFTAVRRSVTVDGVTTDIGLVGDVERVNAAAVLDLIAARRIPVVST
CCCEEEEECCCCHHHHHHHHHHEEECCCEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
LAPDAEGVVHNINADTAAAALAEALGAEKLLMLTDVEGLYTSWPNRDSLVSEIDTATLSQ
CCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHHH
LLPTLEAGMIPKVEACLRAVSAGVPSAHVIDGRVEHCVLVELFTDEGTGTKVVSS
HHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEEEECCCCCCEECCC
>Mature Secondary Structure 
TPSTEALPTAVKAQVLAEALPWLKQLHGKIVVIKYGGNAMTDDTLRRAFAADMAFLRNC
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHC
GIHPVVVHGGGPQITAMLRRLGIPGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINA
CCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
HGPYAVGITGEDAQLFTAVRRSVTVDGVTTDIGLVGDVERVNAAAVLDLIAARRIPVVST
CCCEEEEECCCCHHHHHHHHHHEEECCCEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
LAPDAEGVVHNINADTAAAALAEALGAEKLLMLTDVEGLYTSWPNRDSLVSEIDTATLSQ
CCCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHHH
LLPTLEAGMIPKVEACLRAVSAGVPSAHVIDGRVEHCVLVELFTDEGTGTKVVSS
HHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEEEECCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA